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WASHINGTON, Dec. 7 (Xinhua) -- Drugs that affect the levels of an important brain protein involved in learning and memory reverse cellular changes in the brain seen during aging, according to an animal study published Wednesday in the Journal of Neuroscience. The findings could one day aid in the development of new drugs that enhance cognitive function in older adults.Aging-related memory loss is associated with the gradual deterioration of the structure and function of synapses (the connections between brain cells) in brain regions critical to learning and memory, such as the hippocampus.Recent studies suggested that histone acetylation, a chemical process that controls whether genes are turned on, affects this process. Specifically, it affects brain cells' ability to alter the strength and structure of their connections for information storage, a process known as synaptic plasticity, which is a cellular signature of memory.In the current study, Cui-Wei Xie, of the University of California, Los Angeles, and colleagues found that compared with younger rats, hippocampi from older rats have less brain-derived neurotrophic factor (BDNF) -- a protein that promotes synaptic plasticity -- and less histone acetylation of the Bdnf gene. By treating the hippocampal tissue from older animals with a drug that increased histone acetylation, they were able to restore BDNF production and synaptic plasticity to levels found in younger animals."These findings shed light on why synapses become less efficient and more vulnerable to impairment during aging," said Xie, who led the study. "Such knowledge could help develop new drugs for cognitive aging and aging-related neurodegenerative diseases, such as Alzheimer's disease," she added.
TAIPEI, Dec. 10 (Xinhua) -- A televised debate among three candidates for Taiwan's next deputy leader was staged Saturday, highlighting cross-Strait political and economic issues, for next month's Taiwan leader election.The three candidates touched upon topics such as stances on the reunification of Taiwan and the Chinese mainland and the "Taiwan independence," last year's signing of the cross-Strait Economic Cooperation Framework Agreement (ECFA), among other cross-Strait issues, during the second face-to-face debate before the Jan. 14, 2012 election.Wu Den-yih, who is incumbent Taiwanese leader Ma Ying-jeou's running mate and currently chief of Taiwan's executive authority, said the signing of the ECFA aims to "help people do business and enhance Taiwan's competitiveness." Ma is seeking a second term.The ECFA did not speed up Taiwan's inclination toward the mainland market, but ensured the island's utmost interests instead, Wu said, adding that if Ma, who is also chairman of Taiwan's ruling Kuomintang (KMT) party, did not win during the upcoming election, cross-Strait peace and stability would not be maintained.However, Wu's main rival Su Jia-chyuan, the running mate of Tsai Ing-wen who campaigned for Taiwan's next leader representing major opposition Democratic Progressive Party (DPP), claimed that Taiwan is a "sovereign state" and its fate would be decided by Taiwanese themselves, no matter it would become independent or unified with the mainland, or maintain the status quo.Taiwan's future would be guaranteed only if the so-called "Taiwan consensus," put forward by Tsai, was realized, Su said during the debate.Another debater, Lin Ruey-shiung, 72, the running mate of People First Party (PFP) candidate James Soong, called for the signing of a cross-Strait peace accord, and said that the Chinese nation was fundamentally one family, with reunification benefiting both and secession hurting both.Lin said, as a member of the Chinese nation, Taiwan must be reunified with the mainland in the future, without wars, and it is the aspiration of all Taiwanese that people of both sides could freely visit each other.The three candidates also debated on anti-corruption, financial deficit and social equity.Saturday's debate among the candidates for deputy leader was the second of a three-part series. A debate of the Taiwan leader hopefuls was staged last Saturday, and they will spar again on Dec. 17.
HEFEI, Nov. 25 (Xinhua) -- China's leading private automaker, Chery Automobile Co., Ltd., is expected to export a record 170,000 units of vehicles in 2011, marking the highest annual export figure in the company's history, a company manager said Friday.Chery exported 135,556 units of vehicles in the first ten months of this year, up 77.3 percent from a year earlier. This total accounts for 35.3 percent of total passenger vehicle exports of domestic brands, said Feng Ping, deputy general manager of Chery International.The central Anhui province-based carmaker started exporting cars in 2001, when it sold ten cars to Syria, and has since led export sales amongst Chinese automakers.The company exports its products to more than 80 countries and regions, and has established 3 research institutions, a service network of 1,000 dealers and more than 800 service stations overseas.
BEIJING, Dec. 29 (Xinhua) -- Chinese authorities broke up more than 1,800 dens that made or sold counterfeit drugs in cases that involved 3.35 billion yuan (530 million U.S. dollars) in a two-year crackdown, according to the State Food and Drug Administration (SFDA).During the campaign, 13 government departments mobilized more than one million law enforcement workers to combat the sale of fake drugs via online advertising or consignment, seizing more than 5,000 kinds of illegal products, said SFDA deputy head Bian Zhenjia Thursday at a meeting.According to Bian, the action also targeted malpractice during the manufacturing process as well as selling non-pharmaceutical products as drugs.In the operation, authorities conducted more than 28,000 on-site inspections in medicine production factories and halted the production of 98 varieties of drugs, Bian said.However, Bian noted that problems still exist, including rampant illegal drug advertising and online sales of fake drugs, improper manufacturing practices and outdated laws and regulations concerning drug safety.Bian said the SFDA will continue to cooperate with other government departments and step up supervision and crackdowns on the online sale of fake drugs.
BEIJING, Jan. 14 (Xinhua) -- China and member countries of the Association of Southeast Asian Nations (ASEAN) on Saturday held a meeting of senior officials on the implementation of the Declaration on the Conduct of Parties in South China Sea.All the participants had in-depth discussion and reached a series of consensus, said a press release posted on the Foreign Ministry's official website (www.fmprc.gov.cn).The meeting concluded that the general situation of South China Sea is peaceful and stable, and appreciated the positive efforts from all concerned sides.The meeting regarded 2011 as a fruitful year with positive progress made in implementing the declaration, and reached consensus on the future works, including to speed up specific cooperation projects, and to host seminars on maritime disaster-relief, environment, rescue and biology research.All the parties agreed to set up experts committees on maritime scientific research, environmental protection, security and rescue, and on the crackdown on cross-border crimes, and to better utilize the China-ASEAN fund on maritime cooperation.