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The road to the White House clearly goes through the state of Michigan as both Joe Biden and Donald Trump have been actively campaigning in the state.Michigan has been a state hard-hit economically in recent years as the once thriving auto industry Nationally, the number of auto jobs has declined amid the pandemic. The auto industry has lost nearly 100,000 jobs this year.At the start of the century, there were more than 1.3 million US auto jobs. When Barack Obama took office, that number had dropped by 50%. During his tenure, the auto industry regained a portion of those jobs lost.But any gains from a revamped trade agreement had yet to be realized in the auto industry based on Bureau of Labor Statistics figures. On Thursday, Joe Biden said in an interview with CNN’s Jake Tapper the new USMCA agreement that replaced NAFTA is an upgrade, but failed to give President Donald Trump for securing the agreement."But look what the overall trade policy has done even with NAFTA. We now have this gigantic deficit in trade with Mexico. Not because NAFTA wasn't made better, because overall trade policy and how he deals with it made everything worse," Biden said.Biden was asked whether Trump should be given credit for the USMCA. Biden said the Obama White House was unable to renegotiate NAFTA because of Congress. For the first two years of the Obama administration, both the House and Senate were held by Democrats.“Because we had a Republican Congress that wouldn't go along with us renegotiating,” Biden told Tapper.In 2008, both Biden and Obama campaigned on changing the US trade agreement between Mexico and Canada. The USMCA, which became effective this year, was amended by Congress, but ultimately won bipartisan support from leaders of both party.The interview with Tapper was taped in Michigan and aired hours before Trump held a campaign rally in the state.On Monday, Trump said, “Biden supported NAFTA. He supported China’s entry into the World Trade Organization. Two disasters. The most disastrous trade deals in history, both of them. I can’t tell you which was worse; they were both terrible.” 2125

The U.S. regulators who will decide the fate of COVID-19 vaccines are taking an unusual step: Asking outside scientists if their standards are high enough.The Food and Drug Administration may have to decide by year’s end whether to allow use of the first vaccines against the virus. Thursday, a federal advisory committee pulls back the curtain on that decision process, debating whether the guidelines FDA has set for vaccine developers are rigorous enough.“We will not cut corners, and we will only use science and data to make that determination,” FDA Commissioner Stephen Hahn pledged at a meeting of the Milken Institute Wednesday.Exactly how much data his agency needs to be sure a vaccine is safe and effective is a key question for the advisers. An even bigger one: If the FDA allows emergency use of a vaccine before final testing is finished, will that destroy chances of ever learning just how well that shot -- and maybe competitors still being studied -- really work?“We can’t lose sight of the fact that it is in our societal interest to see these trials to completion,” said Dr. Luciana Borio, a former FDA acting chief scientist who will be watching the advisers’ debate.Plus, multiple vaccines are being studied -- shots made with different technologies that each have pros and cons.“The first vaccine is not necessarily the best vaccine,” cautioned Dr. M. Miles Braun, a former FDA scientist now with Georgetown University School of Medicine. If the trials aren’t allowed to finish, it may be difficult or impossible to ever know for sure.It’s a critical moment in FDA’s 114-year history. The government has spent billions to race a vaccine through a research process that usually takes years, and FDA faces unprecedented pressure from the Trump administration, fueling public skepticism that politics could overrule science.Interest is so high, FDA is airing the meeting on YouTube. Here are some key issues the committee will discuss:HOW MUCH EVIDENCE IS NEEDED?FDA is requiring manufacturers to do studies of at least 30,000 people to prove if a vaccine protects and how safe it is. Those studies must include adequate numbers of people at highest risk from COVID-19 -- older adults, minorities and anyone with underlying health problems.FDA has made clear that any vaccine must be at least 50% effective. And while the studies are designed to run for two years, companies may get enough evidence the shots are protective -- in at least some people -- to stop the trials early and seek what’s called an “emergency use authorization” for wider vaccinations.Despite White House objections, the FDA told vaccine makers earlier this month not to seek that speedier review until they’ve tracked at least half their trial participants for two months. With other vaccines, that’s about the amount of time when major side effects crop up.That’s not long enough, said the head of the non-profit ECRI Institute, which reviews medical technology for hospitals and insurers. In comments submitted to the advisory committee, ECRI’s Dr. Marcus Schabacker said FDA should require six months of follow-up.“Doing any less would simply risk too much, and the consequences may be severe,” he wrote. “A weak vaccine that loses public trust could poison the well for epidemic control for many years.”WOULD EMERGENCY USE DERAIL FULL ANSWERS ABOUT VACCINES?Normally when a study ends because of evidence that a vaccine is working, the participants who got dummy shots are offered the real thing.But if FDA allows emergency use of a COVID-19 vaccine, that’s not the same as having full proof the shot works, Borio cautioned.And if the participants in the placebo group are immediately offered the real shot, researchers may not be able to get answers about all the high-risk groups in the study — or tell how long the vaccine’s protection lasts, a process expected to take many more months.But Pfizer Inc., which with Germany’s BioNTech is developing one of the leading candidates, told FDA that if it’s granted emergency use authorization, it “would have an ethical obligation” to alert study participants who got a placebo and allow them vaccine access. The company wants FDA to look into “other scientifically and statistically sound methods” to determine long-term safety and effectiveness.Pfizer’s stance is likely to face pushback. The Infectious Diseases Society of America states that FDA’s panelists “should insist” that vaccine developers “present a compelling case” for how they will complete their trials if FDA grants early authorization of their vaccine.Clearing a vaccine based on premature or faulty data “could cause more harm” by “further eroding public confidence in all vaccines,” the group said.It’s an unprecedented dilemma. The FDA has previously allowed emergency use of only one vaccine, a decades-old shot that in 2005 was authorized to prevent anthrax poisoning.This time around, multiple COVID-19 vaccines are in the pipeline. Pfizer competitor Johnson & Johnson cautioned that early FDA clearance of one vaccine could “jeopardize integrity” of other ongoing trials if patients decide to drop out to seek the first cleared shot instead.The company asked regulators to explain what options are available to ensure completion of all ongoing COVID-19 vaccine trials.WHAT ABOUT LONG-TERM SAFETY MONITORING?Even a study of 30,000 people cannot spot a side effect that only strikes 1 in 100,000. So the government is planning extra scrutiny of every COVID-19 vaccine to hit the market.At first there will be limited doses given to just certain high-risk people -- and those early recipients are to get text messages daily for the first week after vaccination, and then weekly out to six weeks, asking how they’re feeling.FDA also will be checking databases of electronic health records and insurance claims, looking for any red flags.“There’s a kind of tracking that has to take place here on a massive basis that hasn’t taken place before,” said Dr. Jesse Goodman of Georgetown University, a former director of the FDA’s vaccine and biologics center.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 6274

The Walt Disney Co. is planning to lay off 28,000 workers in its theme parks division in California and Florida.The company has been squeezed by limits on attendance at its parks and other restrictions due to the pandemic. Officials said Tuesday that two-thirds of the planned layoffs involve part-time workers but they ranged from salaried employees to nonunion hourly workers.In addition to the 28,000 nonunion workers, Disney said it is discussing next steps with unionized cast members.Disney’s parks closed last spring as the pandemic started spreading in the U.S. The Florida parks reopened this summer, but the California parks have yet to reopen as the company awaits guidance from the state of California.Disney along with local officials, have pressured California officials to resume operations at Disneyland. Disneyland has been ordered to remain closed by California Gov. Gavin Newsom.Newsom said a month ago that he would have an announcement soon on plans to allow for a reopening of amusement parks in California, including Disneyland.“In light of the prolonged impact of COVID-19 on our business, including limited capacity due to physical distancing requirements and the continued uncertainty regarding the duration of the pandemic – exacerbated in California by the State’s unwillingness to lift restrictions that would allow Disneyland to reopen – we have made the very difficult decision to begin the process of reducing our workforce at our Parks, Experiences and Products segment at all levels, having kept non-working Cast Members on furlough since April, while paying healthcare benefits,” said Josh D’Amaro, Disney Parks chairman. “Approximately 28,000 domestic employees will be affected, of which about 67% are part-time. We are talking with impacted employees as well as to the unions on next steps for union-represented Cast Members.” 1872

The U.S. Marine Corps says it has lifted a "shelter-in-place" order at the Air Ground Combat Center (AGCC) in Twentynine Palms, California following earlier reports of an "active shooter."According to a statement from the Marines, the order was enacted when an "individual" suffered a self-inflicted gunshot wound on the base at about 8:30 a.m. PT. No other injuries were reported. The person who fired the gun has been transported to a local medical center for treatment.The Marines say they are investigating.Shortly after 8:30 a.m., the Marines tweeted that they were "aware of reports" of an active shooter at the AGCC. Later, both KESQ-TV in Palm Springs, California and KTTV-TV in Los Angeles reported — citing a base spokesperson — that a suspect had been taken into custody and that there were no reports of injuries. The Marines later disputed those reports, saying that it could not confirm that a suspect was in custody.The base is located about an hour's drive northwest of Palm Springs. 1008

The Slater fire roared through Happy Camp, California on Sept. 8, and more than a month later, families still can’t get back into their neighborhoods.U.S. Forest Service Officer Jason Rasmussen was working to evacuate families in his community, as his own home was engulfed in flames.He said the fire was like nothing he’s seen in his quiet home town before. “Sounded like some sort of freight train. It was just total chaos. People were scared,” recalled Rasmussen.Winds fueled the flames, leveling 100,000 acres within hours. Two people were killed and nearly 200 homes were lost.“I knew my home was probably going to burn,” said Rasmussen. “I could only hope that it would survive.”Daybreak cemented gut-wrenching worry into reality. This fire left nothing behind for this family and so many others.“It’s heartbreaking seeing my house and my friend’s houses burned to the ground,” said Rasmussen's son, Chaance, who is a firefighter. “The only thing that’s left is memories.”Memories of a home, of a family legacy, built in this town for generations—now reduced to dust.“It’s emotional. I don’t even like to go back there,” said Jason Rasmussen of returning to what was once his home. “The stuff that was special to me was not valuable even. It was stuff that my grandfather had given me. Things that were sentimental for that reason, because it was connected to my family history."This loss is made even harder for the Rasmussens, because they never thought they’d be the ones needing help.“While you’re talking to people you’re evacuating, you’re going through the same thing,” said Jason Rasmussen. “When I knew I was actually homeless, that was the worst feeling.”After a month of moving from place to place, having nowhere to really call home, a surprise came that left these first responders speechless.Volunteers from EmergencyRV.org drove this donated RV from Oregon to Northern California. A woman donated her RV to the organization, and EmergencyRV.org matches up families in need. First responders go to the top of the list.Between being on the frontlines through the pandemic and this natural disaster, this group wanted to give these men a break.“It doesn’t make sense that a firefighter loses his home and is sleeping in a tent or has nowhere to go, sleeping in the station,” said EmergencyRV.org founder Woody Faircloth. “We want to give them a place to call home until they get back on their feet.”“I wasn’t expecting something like this,” said Chaance Rasmussen of the donated RV. “I thought, maybe something I could tow, but then I remembered I didn’t have a truck anymore, so it’s nice to have this.”The RV is giving the young firefighter much more than a place to sleep.“It kind of restores my faith in humanity,” said Chaance Rasmussen. “You see all the bad stuff on the media, people are rioting and all that stuff is happening, and knowing that people are out there doing stuff like this, it’s real heartwarming.”To the volunteers, it’s a thank you for the danger these frontline workers face head-on every day.“These firefighters and frontline heroes…they are heroes,” said Faircloth. “They’re out there every day doing this job, and they don’t make a lot of money, but they’re risking their lives for the rest of us.”A risk this father and son are proud to take on, even as they take on the much tougher challenge of restoring this land into a place they can call home. 3405