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BEIJING, July 26 (Xinhuanet) -- Seven of the 20 top selling American prescription drugs will lose their patents by the end of next year, making way for less expensive generic versions, according to media reports.It's a shift that could save consumers billions of dollars -- assuming those big-ticket medications are willing to give up a trusted brand name for an off-label replacement.The prices of medications such as cholesterol-fighting Lipitor and blood thinner Plavix are expected to go down significantly, according to the U.S. Food and Drug Administration (FDA).Lipitor will lose its patent in November. When that patent expires, people are advised to buy atorvastatin, the generic equivalent. Other brand names include the anti-psychotic Zyprexa and the rheumatoid arthritis and psoriasis drug Enbrel, of which the patent will expire in October and October of next year, respectively.Over the next 10 years, an estimated 120 more brand-name prescription drugs will lose their patents in the U.S.

SINGAPORE, July 6 (Xinhua) -- A team of researchers in Singapore has designed a tube with special robotic hands that allows doctors to perform surgery on a patient's inner organs without resulting in scars, local media reported on Wednesday.The special "robotic hands" were fixed to the tube to access a patient's stomach. Compared with traditional methods which use only one robotic hand, the new device known as master and slave transluminal endoscopic robot, or MASTER, is more nimble, thereby allowing complex operations, the Lianhe Zaobao reported.Louis Phee, an associate professor at the Nanyang Technological University who led the team of researchers, had spent six years to develop the gadget, which cut an eight-hour procedure to just 17 minutes, said doctors at India's Asian Institute of Gastroenterology.The gadget, still in the trial stage, has been tested earlier this month on three patients at the Indian hospital. It is also expected to be tried out in Germany and China's Hong Kong later. The patients can leave the hospital much sooner than they would have using traditional gadgets.Phee said he expected the gadget to be available on the market as early as three years from now, after going through clinical trials and getting the approval from authorities.He also saw a potential for the gadget to be used on other organs by cutting a small spit on stomach that allows the gadget to go through to access the site.

WASHINGTON, Sept. 26 (Xinhua) -- Older people with low blood levels of vitamin B12 markers may be more likely to have lower brain volumes and have problems with their thinking skills, according to researchers at Rush University Medical Center in Chicago.The results of the study will be published Tuesday in Neurology, the medical journal of the American Academy of Neurology.Foods that come from animals, including fish, meat, especially liver, milk, eggs and poultry are usual sources of vitamin B12.The study involved 121 older residents of the south side of Chicago over the age of 65. They had blood drawn to measure levels of vitamin B12 and B12-related markers that can indicate a B12 deficiency. The same subjects took tests measuring their memory and other cognitive skills.An average of four-and-a-half years later, MRI scans of the participants' brains were taken to measure total brain volume and look for other signs of brain damage.Having high levels of four of five markers for vitamin B12 deficiency was associated with having lower scores on the cognitive tests and smaller total brain volume."Our findings definitely deserve further examination," said Christine Tangney, associate professor at Rush University Medical Center and lead author of the study. "It's too early to say whether increasing vitamin B12 levels in older people through diet or supplements could prevent these problems, but it is an interesting question to explore. Findings from a British trial with B vitamin supplementation are also supportive of these outcomes."On the cognitive tests, the scores ranged from -2.18 to 1.42, with an average of 0.23. For each increase of one micromole per liter of homocysteine -- one of the markers of B12 deficiency -- the cognitive scores decreased by 0.03 standardized units or points.Tangney noted that the level of vitamin B12 itself in the blood was not associated with cognitive problems or loss in brain volume. "Our findings lend support for the contention that poor vitamin B12 status is a potential risk factor for brain atrophy and may contribute to cognitive impairment," said Tangney.

UNITED NATIONS, June 8 (Xinhua) -- Marking 30 years of the HIV- AIDS pandemic, scores of heads of state and government and ministers took to the UN General Assembly podium on Wednesday to list their country's accomplishments and list challenges in the battle.The General Assembly High Level Meeting on AIDS is taking place 10 years after the UN Special Session on HIV/AIDS and also marks five years since signing of the Political Declaration in which UN member states committed to moving towards universal access to HIV prevention, treatment, care and support.UN Secretary-General Ban Ki-moon UN recalled how three decades ago AIDS was spreading while "Today, we have a chance to end this epidemic once and for all."Now, instead of fear, there is hope, he said."Today, HIV is on a steep decline in some of the most affected countries. Countries like Ethiopia, South Africa, Zambia and Zimbabwe," he said. "They had the largest epidemics in the world, and they have cut infection rates by one quarter.""Globally, more than 6 million people now get treatment," Ban said. "All of these advances come thanks to you and the commitments you made, first 10 years ago and then again in 2006. Today, the challenge has changed. Today, we gather to end AIDS."However, President Joseph Deiss of the General Assembly said 10 million people still have no access to treatment and far too many people were still being infected, adding it was necessary to continue complementary and closely-linked prevention, treatment, care and support measures."We have reached a critical moment in time," he said. "We must take a holistic approach and integrate the response to AIDS into broader development programs."Michel Sidibe, executive director of the Joint UN Program on HIV/AIDS (UNAIDS), recalled how 30 years the disease was called the gay plague and slime disease. People were afraid of each other and there was no hope."This image should not disappear. It is part of our history," he said.Sidibe said the AIDS movement was the story of a people breaking the conspiracy of silence, demanding equity and dignity, confronting societies'wrongs, seizing their rights, and making a passionate call for social justice. Since then, a compact had been made between the global North and the South, which had produced lifesaving results.Now, More than 6.6 million people are being treated in low- and middle- income countries, he said, pointing out that since the initial success stories in Uganda and Thailand 56 countries, including 36 in Africa, have been able to stabilize the epidemic and reduce the number of infections significantly.Infections have been reduced by 35 percent in South Africa and by more than half in India, the UNAIDS chief said. In China, the HIV mortality rate had fallen by 64 percent, Sidibe said. Many other countries had reached universal access to treatment.He voiced what was repeated several times, and that was a call for "a transformational agenda" of "zero infections, zero discrimination and zero AIDS-related deaths."To put a personal face on the disease, a woman from Ukraine openly living with HIV, Tetyana Afansiadi, told her story to the delegates.She told how she had been living with HIV and using drugs for 13 years, had hepatitis C for almost 11 years but now has a husband and an 8-year-old son. Neither have HIV.Three years ago she took part in a drug therapy program that has enabled her to live, work, and take care of her son."Drug dependency and HIV-infection require treatment, not prosecution," she said.Given that opioid substitution therapy in her home city had changed the lives of people like her, it was time to stop refusing antiretroviral treatment to people who used drugs.While the heads of states and government and ministers, usually those heading up health departments, spoke in the General Assembly hall under bright lights, scores more of delegates attended five panel sessions and about 40 individual side events.Some samplings from the spotlighted dark-green podium in the great hall:President Paul Kagame of Rwanda, said, "It is time to galvanize member states to commit to a transformative agenda that overcomes the barriers to an effective, equitable and sustainable response to HIV and AIDS."Jose Angel Cordova Villalobos, health minister of Mexico, called for states to implement friendly, non-discriminatory healthcare systems as well as sex education in order to prevent the spread of HIV/AIDS."To achieve this, we call to all the countries congregated here today in order that your actions are based in the framework of respect to the human rights and focusing on gender equity, that allow to consolidate an effective response to the HIV/AIDS without stigmas, discrimination, homophobia, transphobia; as well as any type of violence," he said, referring, in part, to transsexuals.The vice president of Mauritius, Monique Bellepeau, said, "The adverse impact of the AIDS epidemic on the socioeconomic progress, particularly in the developing countries, dictates that there is no time for complacency."She added, "After wrestling with AIDS for the past three decades, we are today equipped with a vast body of knowledge and various new tools to urgently complete the task. No less than strict prevention efforts and universal access to treatment, care and support are required."The speeches continue Thursday and on the final day of the three-day meeting, UN member states are expected to adopt a declaration to guide country responses to HIV over the next five years.