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President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890
President Donald Trump told reporters on Tuesday that he plans on announcing his nomination to replace Justice Ruth Bader Ginsburg on Saturday at 5 p.m. ET.It does not appear there will be any drama involving the confirmation of a new justice after Sen. Mitt Romney announced earlier on Tuesday he will not stand in the way of Trump’s nominee. Only two Republican senators - Lisa Murkowski of Alaska and Susan Collins of Maine - say they oppose holding a confirmation vote amid an election. With just Murkowski and Collins joining Democrats in opposing a confirmation close to the election, Republicans will likely have 51 votes to confirm Trump’s nominee.On Monday, Trump said he is choosing among five women to nominate to the Supreme Court by the end of the week, and is pushing for the nominee to be confirmed by Election Day.On Tuesday, Trump said he wants to see a full bench of nine justices in place by the election in order to oversee any potential election challenges.While the Supreme Court has given a 5-4 advantage to conservatives for many years, Chief Justice John Roberts has occasionally sided with the four liberal justices on key votes, including challenges on the Affordable Care Act. With Ginsburg’s death, the court will give conservatives a 6-3 edge, and gives the party hope of overturning Roe versus Wade and the Affordable Care Act. 1366
RAMONA, Calif. (KGTV) - The young man found shot to death in a Ramona home was identified by his roommate Monday as a resident of Ukraine.San Diego County Sheriff's deputies got a 911 call reporting Sunday at 8 p.m. reporting shots fired near the home on Wood Rock Lane. They found the victim dead inside.Four people live in the home, including Ben Ledbetter. He said the victim, a 20-year-old man, worked for Ledbetter's mobile detailing business for four years. Ledbetter believes he is being targeted and said someone killed his best friend out of anger."He's 100 percent good. His heart is strong, his will is strong. His attitude was positive. You couldn't kill a better person. He was the best person you could ever know," Ledbetter said.The victim's name is being withheld until his family can be notified.Deputies shut down the area near the home until 1 p.m. Monday to search for evidence. Ledbetter told 10News that detectives took his phone, truck and clothes as part of the investigation.Anyone with information on the incident is urged to contact sheriff’s Homicide Detail at 858-974-2321 or 858-565-5200. 1182
President Donald Trump will meet with North Korean leader Kim Jong Un by May, the South Korean national security adviser announced Thursday at the White House.Kim told the South Koreans "he is committed to denuclearization" and pledged North Korea will "refrain from any further nuclear or missile tests" South Korean national security adviser Chung Eui-Yong said Thursday from the White House.Kim also told the South Koreans he understands that the US and South Korea will move forward with their joint military exercises later this year."He expressed his eagerness to meet President Trump as soon as possible," Chung said. 632
President Donald Trump will not meet North Korean leader Kim Jong Un next month for what would have been a historic diplomatic summit, he announced in a letter to Kim released by the White House Thursday morning."I was very much looking forward to being there with you. Sadly, based on the tremendous anger and open hostility displayed in your most recent statement, I feel it is inappropriate, at this time, to have this long-planned meeting," Trump wrote. "Therefore, please let this letter serve to represent that the Singapore summit, for the good of both parties, but to the detriment of the world, will not take place." 639