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SAN FRANCISCO, May 3 (Xinhua) -- Microsoft announced on Tuesday that its Bing search engine will become the default search and mapping application on Blackberry phones.Microsoft Chief Executive Officer Steve Ballmer announced the partnership with Research in Motion (RIM), which makes Blackberry phones, at the Blackberry World Conference in Orlando, Florida, according to a Microsoft blog post.Ballmer said Microsoft would invest uniquely in the Blackberry platform in addition to its own Windows Phone platform."Bing will be deeply integrated at the BlackBerry OS (operating system) level," Ballmer said.Central to the collaboration, Blackberry devices will use Bing as the preferred search provider in the browser, and Bing will be the default search and map application for new devices presented to mobile operators, both in the United States and internationally, said Microsoft's Bing team in the blog post.Meanwhile, Bing is also shipping as the default search experience and map application for the newly released Blackberry Playbook, a RIM tablet computer which made market debut on April 19.On Tuesday's Blackberry conference, Ballmer called Google's Android ecosystem "chaos" and the Apple iOS "limited" before he hailed Windows Phone 7 and Blackberry. Microsoft and RIM are both competing with Apple, which makes the iPhone and iPad, and Google, which makes the Android operating system for smartphones and tablets in the booming mobile device market.

WASHINGTON, April 25 (Xinhua) -- Study by scientists at the Rockefeller University shows that anti-inflammatory drugs reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors (SSRIs), taken for depression and obsessive-compulsive disorder and anxiety disorders.This discovery, published online Monday in the Proceedings of the National Academy of Sciences, may explain why so many depressed patients taking SSRIs do not respond to antidepressant treatment and suggests that this lack of effectiveness may be preventable.The study may be especially significant in the case of Alzheimer's disease. Such patients commonly suffer from depression and unless this can be treated successfully, the course of the illness is likely to be more severe. Depression in the elderly is also a risk factor for developing Alzheimer's Disease and researchers have suggested that treating depression in the elderly might reduce the risk of developing the disease.In the recent study, investigators treated mice with antidepressants in the presence or absence of anti-inflammatory drugs. They then examined how the mice behaved in tasks that are sensitive to antidepressant treatment. They found that the mice's behavioral responses to antidepressants were inhibited by anti- inflammatory/analgesic treatments.They then confirmed these effects in a human population. Depressed individuals who reported anti-inflammatory drug use were much less likely to have their symptoms relieved by an antidepressant than depressed patients who reported no anti- inflammatory drug use. The effect was rather dramatic since, in the absence of any anti-inflammatory or analgesic use, 54 percent of patients responded to the antidepressant, whereas success rates dropped to approximately 40 percent for those who reported using anti-inflammatory agents."Many elderly individuals suffering from depression also have arthritic or related diseases and as a consequence are taking both antidepressant and anti-inflammatory medications. Our results suggest that physicians should carefully balance the advantages and disadvantages of continuing anti-inflammatory therapy in patients being treated with antidepressant medications," leader author Paul Greengard said.

WELLINGTON, May 13 (Xinhua) -- While it's long been known that a little sunshine can spread happiness, researchers in New Zealand have found that it can also save the lives of pneumonia patients.Medical scientists have found that vitamin D, which is absorbed through the skin and produced with exposure to sunlight, is a major factor in the survival rate of pneumonia patients.Researchers at Waikato University collaborated with doctors at Waikato Hospital, both Hamilton-based institutions, to study blood samples of 112 patients admitted to the hospital with pneumonia during the winter.They found that those with severe vitamin D deficiency 17 of the patients were more likely to die within a month, compared with patients with normal or slightly low vitamin D levels.Dr Bob Hancox, of the hospital's department of respiratory medicine, said five of the 17 died, a 29-percent mortality rate, compared with four deaths among the 95 patients with higher vitamin D levels, a 4-percent mortality rate."The analysis confirmed that the difference in mortality rates between the two groups was very unlikely to be due to chance," Hancox told Xinhua.Vitamin D deficiency was a concern around the world, Hancox said."Sunlight is the main source of vitamin D, so it tends to be a winter problem in temperate climates when people spend a lot of time indoors. But it occurs in all countries and vitamin D deficiency is believed to be a major problem worldwide."There is accumulating evidence that we need vitamin D to help fight infections, such as pneumonia as we have shown, as well as improve bone health," he told Xinhua."What is not yet clear is whether we can do anything about it. We don't know whether treating people with vitamin D supplements would help to prevent or treat respiratory infections. This is what we need to find out now."Dr Ray Cursons, of the Biological Sciences department at Waikato University, said patient age, sex, additional health conditions, and other prognostic factors did not affect the research outcome, although researchers still could not establish a causal link between vitamin D deficiency and mortality in the patients.Waikato Hospital D respiratory specialist Dr Noel Karalus said it was not yet known whether giving patients vitamin D supplements after their admission to hospital with respiratory tract infections would alter outcomes."It may transpire that vitamin D helps us avoid infection rather than cure it once established."Cursons said the best source of vitamin D was sunlight as dietary sources such as fatty fish and cod liver oil did not contain enough vitamin D."There is still some controversy regarding the optimal daily allowance of vitamin D. How much we absorb through the skin depends on sun exposure, skin type and geographical latitude. M ori and Pacific Islanders absorb less because of their darker skin, and people in colder climates also have lower levels of vitamin D. "Pneumonia is the single largest cause of death in children worldwide, killing an estimated 1.6 million children under the age of five each year, according to the World Health Organization.The research findings are published in the journal Respirology, published by the Asian Pacific Society of Respirology, this month.

SAN FRANCISCO, April 8 (Xinhua) -- YouTube on Friday launched YouTube Live, a homepage for live content on the site and a new live-streaming platform.As part of the service, the world's largest video-sharing website introduced a new browse page, www.youtube.com/live, where users can view live events and add upcoming events to their calendars.YouTube said it would gradually roll out a live streaming beta platform, which will allow certain YouTube partners with accounts to stream live content on the website.The new service will "integrate live streaming capabilities and discovery tools directly into the YouTube platform for the first time," YouTube said in a blog post.U.S. media recently reported that YouTube is planning a major overhaul and is negotiating with Hollywood and music producers for materials to offer on a lineup of new channels, with the aim to compete with broadcast and cable television.

WASHINGTON, April 6 (Xinhua) -- A study led by researchers at the University of Michigan (U-M) showed in animal studies that new cancer drug compounds they developed shrank tumors, with few side effects.The study, done in two mouse models of human cancer, looked at two compounds designed to activate a protein that kills cancer cells. The protein, p53, is inactivated in a significant number of human cancers. In some cases, it is because another protein, MDM2, binds to p53 and blocks its tumor suppresser function. This allows the tumor to grow unchecked. The new compounds block MDM2 from binding to p53, consequently activating p53."For the first time, we showed that activation of p53 by our highly potent and optimized MDM2 inhibitors can achieve complete tumor regression in a mouse model of human cancer," says lead study author Shaomeng Wang, director of the Cancer Drug Discovery Program at the U-M Comprehensive Cancer Center.Wang presented the study Wednesday at the American Association for Cancer Research 102nd annual meeting.Many traditional cancer drugs also activate p53 but they do so by causing DNA damage in both tumor cells and normal cells, causing side effects. These new MDM2 inhibitors activate p53 while avoiding the DNA damage common with other drugs. In this study, which was done in collaboration with Ascenta Therapeutics and Sanonfi-Aventis, researchers showed that these new drugs shrank tumors without significant side effects.Because p53 is involved in all types of human cancer, the new drug has potential to be used in multiple types of cancer. Further, the researchers also identified certain markers in tumors that predict which ones will be particularly sensitive to the MDM2 inhibitor, which would allow physicians to target the drug only to patients most likely to benefit.