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The U.S. will pay drug company Pfizer .95 billion to produce and deliver 100 million doses of the company's COVID-19 vaccine candidate should the drug prove effective in human trials the company said in a press release on Wednesday.Pfizer will deliver the vaccine if and when the drug receives Emergency Use Authorization from the FDA after a large-scale Phase 3 trial.According to the reports, the deal includes an option for the government to purchase an additional 500 million doses of the vaccine.“Expanding Operation Warp Speed’s diverse portfolio by adding a vaccine from Pfizer and BioNTech increases the odds that we will have a safe, effective vaccine as soon as the end of this year,” Health and Human Services Sec. Alex Azar said in a statement. “Depending on success in clinical trials, today’s agreement will enable the delivery of approximately 100 million doses of this vaccine to the American people.”Pfizer and German firm BioNTech are working together to develop the vaccine.On Monday, Pfizer said in a press release that results from Phases 1 and 2 of a German trial indicated that the drug "could potentially be administered safely, with a manageable tolerability profile," according to data from the tests.Biotech company Moderna is also working to develop a coronavirus vaccine. That candidate will move into Phase 3 testing by the end of the month, and the government has also agreed to purchase and distribute the drug should the large-scale test prove effective. 1497

The Wake Forest Institute for Regenerative Medicine says it has a new use for its bioprinting system. In the past they've 3D printed normal-size organs and tissues in hopes of someday implanting them in patients.For the coronavirus, the lab is creating organs using human cells that can be as small as a pinhead. They're focusing on the organs most likely to be infected by the disease. like the lungs.“And so we've been playing with a number of agents to, on both prongs what can make it more infective, what can make it less infective to try to sort this out for the future,” Anthony Atala, director for the institute said.Atala says he hopes the system will help in testing drugs before they hit the market.Drug companies do extensive testing and clinical trials in people before releasing a new medication.Atala says sometimes those companies find no serious side effects, but then years later, discover that it's toxic to patients taking it. Atala says testing a drug using the bioprinting system can tell if a drug is toxic in weeks instead of after years on the market.“Even though we've used the tool extensively for toxicity testing, it's also a tool that can be used for screening,” Atala said. “So we can test agents that are currently being considered for testing against COVID and test the efficacy of the treatment on miniature human organs made up of normal cells”To be clear, Atala said drug tests on 3D printer organs are not meant to replace clinical trials in humans, be are an added step to better predict what will happen in those trials. 1567

The three wildfires currently burning in California are moving across land with a terrifying speed.At its fastest, the Camp Fire in Northern California spread at more than a football field a second, or around 80 football fields per minute. It burned through 20,000 acres in less than 14 hours on Thursday. By Friday, it had reached 90,000 acres.PHOTOS: 3 wildfires rage in CaliforniaThe Woolsey Fire in Ventura and Los Angeles counties doubled in size in a 90-minute period Friday morning, to 8,000 acres -- by Friday evening, it was up to 35,000 acres.The Hill Fire in Ventura County torched 10,000 acres in six hours Thursday.Why are the fires moving so quickly?The combination of strong offshore winds that have been gusting as high as 70 mph, humidity values in the single digits and extremely dry conditions are leading to the perfect conditions for wildfires 872

The vice presidential debate between Mike Pence and Kamala Harris next week will go on as scheduled after President Donald Trump, the First Lady, and others have tested positive for the coronavirus on Friday.An official with the Commission on Presidential Debates confirmed that no changes are anticipated to the Wednesday night debate in Salt Lake City. Both Pence and Harris underwent tests for the coronavirus on Friday and tested negative.Pence’s physician said in a memo that the vice president was not considered a “close contact” of anyone infected with COVID-19 and was not required to quarantine.“Vice President Mike Pence remains in good health and is free to go about his normal activities,” said Navy Lt. Commander Dr. Jesse Schonau in a statement.The one debate between the vice presidential candidates will take place Wednesday in Salt Lake City at the University of Utah. It will be moderated by Susan Page, the Washington Bureau Chief for USA Today. 974

The U.S. reported 2,473 deaths caused by COVID-19 on Tuesday, the highest number of deaths linked to the virus in a single day since the height of the pandemic in May.According to the COVID Tracking Project, the nearly 2,500 deaths are the most the U.S. has seen since May 7 — the deadliest day of the pandemic thus far, when 2,769 COVID-19 deaths were reported.Tuesday also marked the sixth-deadliest day since the pandemic began.Deaths linked to COVID-19 have been on the rise since October — though the 7-day rolling average of deaths linked to the virus has dipped in recent days, likely due to a lack of reports from the Thanksgiving holiday. From Oct. 1 to Dec. 1, the 7-day average of reported COVID-19 deaths has more than doubled from 705 to 1,520. The rise in deaths mirrors a frightening rise in COVID-19 cases. According to the COVID Tracking Project, the U.S. has recorded at least 100,000 new cases of the virus every day since Nov. 3. Since that time, the rolling 7-day average of new cases has nearly doubled from about 85.000 a day to about 159,000 a day.And health experts expect deaths and caseloads to further increase in the coming weeks. Dr. Deborah Birx, a member of the White House coronavirus task force, says the U.S. finds itself in a "very dangerous place" following the Thanksgiving holiday. She says anyone who attended a Thanksgiving gathering last week should assume they are infected with COVID-19 and take appropriate precautions. With more than a million Americans boarding airplanes on Sunday alone following the Thanksgiving holiday, health experts fear cases will skyrocket in the coming days.They also expect hospitals — already overtaxed by current COVID-19 caseloads — to admit even more patients with the virus. Currently, the COVID Tracking Project reports that 99,000 Americans are hospitalized with the virus, forcing some facilities to institute overflow areas. 1925