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WASHINGTON, Sept. 14 (Xinhua) -- Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published Wednesday in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.The endometrium or uterine lining, is a source of adult stem cells. These cells generate uterine tissue each month as part of the menstrual cycle. Like other stem cells, however, they can divide to form other kinds of cells.Led by Yale Professor Hugh Taylor, the researchers bathed endometrial stem cells in cultures containing special nutrients and growth factors. Responding to these substances, the endometrial stem cells adopted the characteristics of beta cells in the pancreas that produce insulin. Over the course of a three- week incubation process, the endometrial stem cells took on the shape of beta cells and began to make proteins typically made by beta cells. Some of these cells also produced insulin.After a meal, the body breaks food down into components like the sugar glucose, which then circulates in the blood. In response, beta cells release insulin, which allows the body's cells to take in the circulating glucose. In this study, Taylor and his team exposed the mature stem cells to glucose and found that, like typical beta cells, the cultured cells responded by producing insulin. The team then injected diabetic mice with the mature, insulin-making stem cells. The mice had few working beta cells and very high levels of blood glucose.Mice that did not receive the stem cell therapy continued having high blood sugar levels, developed cataracts and were lethargic. In contrast, mice that received the cell therapy were active and did not develop cataracts, but the animals' blood sugar levels remained higher than normal.The Yale team's findings suggest that endometrial stem cells could be used to develop insulin-producing islet cells, which are found in the pancreas. These islet cells could then be used to advance the study of islet cell transplantation to treat people with diabetes.Taylor said in a statement that the next step in the research will be to verify how long this treatment remains effective.
BEIJING, July 19 (Xinhuanet) -- Amazon on Monday launched its Kindle textbook rental service, which allows students to rent "tens of thousands of textbooks", according to Los Angeles Times.The e-book textbook rental service will help students save as much as 80 percent on some titles.Amazon said that students can now rent textbooks from 30 to 360 days and can either rent them again or purchase them once the rental period is up."Students tell us that they enjoy the low prices we offer on new and used print textbooks. Now we're excited to offer students an option to rent Kindle textbooks and only pay for the time they need—with savings up to 80 percent off the print list price on a 30-day rental," Dave Limp, vice president of Amazon Kindle said, according to PC Magazine.Rentals can be read on Amazon's Kindle eReaders, and Kindle apps for PCs, as well as smartphones and tablet computers running Apple's iOS, Microsoft Windows Phone 7 and Google's Android operating system.Rentals also have a clear advantage over physical copies that students' notes and highlighted content will be stored in the Amazon Cloud, and can be accessed if students rent the books again or buy at a later time.
BONN, Germany, June 17 (Xinhua) -- The latest United Nations (UN) climate talks ended here on Friday with no surprise -- some " technical issues" saw some progress, as delegates usually said, while major disagreements remained.The two-week UN climate negotiations have made "clear advances" on such issues as extending carbon trading mechanisms, climate fund management and slowing deforestation, Christiana Figueres, UN Framework Convention on Climate Change (UNFCCC) executive secretary, said at a closing press conference.Figueres said delegates from 183 countries stepped forward with a technology mechanism to boost global green technology sharing. The mechanism will include a Climate Technology Center and Network to establish a worldwide clean technology stakeholder community.As for the implementation of a comprehensive package of the Cancun summit last year, this Bonn session has "paved the way" for progress at the next UN ministerial-level climate conference, which is to be held in Durban, South Africa from Nov. 28 to Dec. 9, Figueres said."Strong convergence has emerged on how the Adaptation Committee will be governed, what its composition will be and what its specific role will be," she said. "This progress means that the Committee could be fully operationalized at Durban."The UN climate chief stressed that governments, business circles and civil society cannot solve issues related to climate change "in one meeting," and climate talks are "the most important " negotiations the world has ever seen."The Bonn meeting is practical, focusing on concrete issues. In general, the negotiating process is moving forward step by step and on the right track," Su Wei, China's chief negotiator, told Xinhua on Friday."Despite setbacks and reversals, parties are taking climate change seriously and are willing to promote the negotiations under the Bali Roadmap," he said. "In the past two weeks, contact groups are busy making informal consultations on various topics.""Admittedly, in some key areas, there is a gap among parties," Su said.During the meeting, many delegates and observers have complained that the pace of negotiation was unbearably slow, especially against the backdrop of a new warning from the International Energy Agency, which said the global energy-related carbon emissions rose to a record high in 2010 despite decade-long efforts on curbs.Experts said one of the main hurdles in current talks was still the old topic -- the fate of the Kyoto Protocol, the sole legally- binding pact on industrial countries' emission cuts set to expire at the end of 2012.The protocol, which binds 37 rich countries, has been crippled since Cancun, as Japan, Canada and Russia have clearly stated they would not extend the pact's second commitment period after 2012.The United States, which never ratified the treaty, said it would not accept any legal deal unless other major economies have similar emission constraints.The European Union (EU), the last major bloc that is open to the renewing of the Kyoto Protocol, said its supportive attitude should not be taken for granted. The EU said it would not unilaterally step up efforts on combating climate change if other nations are not willing to do the same.Meanwhile, developing countries insisted that the updating of the Kyoto Protocol remains "the very core issue" of current talks, asking rich nations to shoulder their historical responsibilities and preserve the pact as a major legally-binding instrument to tackle climate change.The Group of 77 and China, representing over 130 developing nations, have said that the renewal of the Protocol should be the priority for Durban.On Friday, Figueres said that "resolving the future of the Kyoto Protocol is an essential task this year and will require high-level political guidance.""By Durban, governments need to come forward with options that will be acceptable to all parties," she said, adding that high- level contacts are necessary to break the ice.She told reporters that environment ministers are due to meet in Berlin from July 3 to 4, known as a continuation of last year's ministerial-level informal talks held in the town of Petersburg near Bonn. Moreover, world leaders are due to discuss climate change on the sidelines of the UN General Assembly in September.Before the Durban summit, delegates have agreed to hold an additional round of climate talks in late September or early October, Figueres revealed.
BERLIN, June 8 (Xinhua) -- German health minister Daniel Bahr expressed cautious hope Wednesday for an end to the wave of E. coli infections as authorities reported two more deaths and more than 300 new cases."I can't give an all-clear, but after the analysis of the latest data we have reasons for hope, as the number of new infections is continuously dropping," Bahr told local public television ARD before an emergency meeting in Berlin with European Union Health Commissioner John Dalli."Unfortunately, there will be new cases and more deaths have to be expected, but overall new infections are clearly going down," he said.On the same day, Germany's national disease control center, the Robert Koch Institute, said the number of reported cases in Germany had risen by more than 300 to 2,648. Nearly 700 of those affected have been taken to hospital with a serious complication that can cause kidney failure.The Institute did not fully support Bahr's optimism. It said there was a declining trend in new cases but added it was not clear whether this was because the outbreak was truly waning or because consumers were staying away from the raw vegetables believed to be the source of the E. coli.The German government has faced increasing criticism from abroad and at home over its dealing with the crisis. It was twice wrong in naming the source of the outbreak and it has been criticized for a lack of coordination between research institutes.Dalli was quoted by local daily Die Welt as saying, "we have to rely on the experience and expertise across Europe, and even outside Europe."The Max Planck Institute for Infection Biology in Berlin also called for a federal government representative to coordinate the various government agencies dealing with the disease to eliminate mixed messages.