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As questions arise over when a coronavirus vaccine should be granted FDA approval, the leaders of several major pharmaceutical companies announced they have signed a pledge not to rush the development of a vaccine.The companies, AstraZeneca, BioNTech, GlaxoSmithKline, Johnson, Merck, Moderna, Novavax, Pfizer and Sanofi, released a joint statement on Tuesday confirming the pledge.The pledge includes the following points:Always make the safety and well-being of vaccinated individuals our top priority.Continue to adhere to high scientific and ethical standards regarding the conduct of clinical trials and the rigor of manufacturing processes.Only submit for approval or emergency use authorization after demonstrating safety and efficacy through a Phase 3 clinical study that is designed and conducted to meet requirements of expert regulatory authorities such as FDA.Work to ensure a sufficient supply and range of vaccine options, including those suitable for global access.There has been pressure on both the FDA and manufactures to develop and approve a vaccine for the coronavirus. There have been more than 190,000 coronavirus-related deaths in the US since March, and the economic impact of the virus has cost millions of jobs.While most developed countries have not had the same public health pain as the US, the economic impact of the virus has been felt worldwide. The International Monetary Fund estimates a nearly 5% loss in global GDP in 2020.In Russia, the country claimed to begin distributing a coronavirus vaccine despite US-based vaccine candidates likely being months away from being able to demonstrate efficacy.The pressure domestically has also ratcheted up as President Donald Trump has suggested a vaccine could be ready by this fall’s presidential election."We're going to have a vaccine very soon... maybe even before a very special date, you know what date I'm talking about,” Trump said on Monday.In late August, the CDC told states to begin to prepare distributing a vaccine by Nov. 1. But Surgeon General Jerome Adams said that just because states will be ready to help distribute a vaccine on Nov. 1 does not mean a vaccine will be ready by then."We've always said that we're hopeful for a vaccine by the end of this year or the beginning of next year,” Adams told Good Morning America."We want to make sure states are available to distribute it," he added.The companies signing on the pledge said that the FDA has strict protocols for vaccine candidates. A typical vaccine trial takes one to three years, but the companies believe only a safe and effective vaccine will be granted approval.“FDA has established clear guidance for the development of COVID-19 vaccines and clear criteria for their potential authorization or approval in the US,” the companies wrote in the pledge. “FDA’s guidance and criteria are based on the scientific and medical principles necessary to clearly demonstrate the safety and efficacy of potential COVID-19 vaccines. More specifically, the agency requires that scientific evidence for regulatory approval must come from large, high quality clinical trials that are randomized and observer-blinded, with an expectation of appropriately designed studies with significant numbers of participants across diverse populations.” 3296
AURORA, Colo. — Three Aurora police officers under investigation for a photograph taken near the site where Elijah McClain struggled with officers were seen in the picture imitating the carotid hold used on McClain by police before the 23-year-old Black man died last August, two sources with knowledge of the situation told KMGH on Tuesday.Neither source had personally seen the photograph of the officers as of Tuesday afternoon, though they were aware of what the photograph showed.Aurora Interim Police Chief Vanessa Wilson on Monday night announced the officers were being investigated for a photograph but declined to say what the photograph showed.Aurora Mayor Mike Coffman on Tuesday tweeted that he was "deeply concerned over the facts surrounding the photographs," but Coffman also did not detail what was shown in the photographs.The officers were notified of their disciplines on Tuesday morning, the sources told KMGH, but the punishments were not yet public. Officers have a three-day period to appeal the discipline, the sources said.The picture depicting the involved officers was sent in a group text to other officers before it was reported to police officials, the sources said.Earlier Tuesday, Aurora police spokesperson Officer Matthew Longshore said the photos were reported to the department by a fellow Aurora officer, which the sources said occurred last Thursday. He said the police chief review board – comprised of the department’s three division chiefs and the deputy police chief – were reviewing the photos and will make a decision on whether, or how to, punish the officers.Longshore said that the officers could potentially be terminated depending on the review board’s decision. Officers would also be able to appeal the decision.The investigation will be “publicly released in its entirety promptly upon its conclusion,” said Wilson, adding the investigation will include reports, photographic evidence, officer’s names, “and my final determination which can rise to the level of termination.”Mari Newman, the attorney for McClain’s family, said in a statement Tuesday morning that APD found “a new low.”“This is a department where officers tackled an innocent young black man for no reason, inflicted outrageous force - including two carotid chokeholds - for fifteen minutes as he pled for his life, joked when he vomited, and threatened to sic a dog on him for not lying still enough as he was dying,” Newman said in a statement. “They tampered with their body cameras to hide the evidence. They exonerated the killers. They deployed riot police and spewed pepper gas on peaceful protestors at a vigil of mourners playing the violin. And now this.”Omar Montgomery, president of the Aurora branch of the NAACP, said Tuesday afternoon that he had not seen the photographs in question but said the issue "is something that further erodes that relationship" between Aurora police and the community.Monday’s announcement was the latest in a series of public relations disasters over the past year for the embattled police department.Earlier Monday, Wilson spoke to KMGH and other local news outlets after her officers pepper-sprayed protesters during a Saturday demonstration in which hundreds gathered to demand justice in the death of the 23-year-old, who died after the encounter with police in August of last year. Wilson made no mention of this internal affairs investigation Monday evening, despite pledging to show transparency and rebuild trust in the department when she took on the job at the beginning of the year.Wilson defended the actions of the officers, claiming agitators were throwing rocks at officers and were trying to breach fences protecting the Aurora Police Department headquarters.Coffman has called for a special city council meeting Tuesday to hear from police about their response to Saturday's protests over the death of Elijah McClain. Attorney General Phil Weiser was named as the state's independent investigator in the case last week.Gov. Jared Polis said at a news conference Tuesday afternoon that it was important for law enforcement agencies across the state to develop trust with the communities they serve.This story was originally published by Ryan Osborne and Jennifer Kovaleski at KMGH, with contributions from Adi Guajardo and Oscar Contreras. 4328

As parents are deciding whether to purchase Halloween costumes for their children amid the coronavirus pandemic, one Ohio man is ready to safely welcome trick or treaters to his home.Andrew Beattie has installed a 6-foot chute for candy so he can remain distanced from trick or treaters on Beggars’ Night.Beattie says that the chute will be “touch-free” as children will have the treats drop into their candy bucket without having to come in contact with Beattie. For added safety, Beattie says that he will wear a mask and continually change gloves in order to keep children safe.“I want our youngins to be able to have some sense of normalcy and maybe a little bit of exercise in all this madness, and I've put a LOT of thought into how to do so safely, and I appreciate your concern,” Beattie said in a viral Facebook post published earlier this week.Beattie said the chute is a six-foot long tube of cardboard that is four inches in diameter. He said he was able to install the chute on his porch in 20 minutes.“If this candy chute makes things easier or safer, AND gives those with mobility challenges more of a chance to participate, then what's the harm? An ounce of prevention is worth a pound of cure, ya' know,” Beattie wrote.Beattie has created a Facebook group where he hopes to share ideas with others this fall ahead of Halloween. The group has nearly 10,000 members as of late Thursday. 1409
Babies have such a bad reputation when it comes to staying quiet on plane rides that some parents go so far as to hand out treats to fellow passengers before the plane has even taken off. Indeed, George and Amal Clooney, world travelers and parents of twin babies, made headlines late last year for gifting headphones to some passengers, along with a note apologizing in advance for any crying.While there’s no need to pack dozens of gifts in your diaper bag, travel and parenting experts recommend other strategies to increase your chances of a smooth flight with your baby. 603
BAKERSFIELD, Calif. (AP) — The California Highway Patrol says an officer conducting a routine traffic stop found ,000 of stolen Disney merchandise.The CHP says a Nissan Sentra was pulled over Friday in Kern County after the driver failed to stop when approaching a school bus.The officer learned the driver's license was suspended and then discovered hundreds of pins and other merchandise allegedly stolen from Disneyland.Officials didn't immediately identify the motorist.Authorities say the CHP has contacted Disneyland security and made arrangements to return the property. 588
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