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SAN DIEGO (KGTV) - After moving to San Diego almost three years ago, Derek and Terri Ruff are on a mission to experience everything the city has to offer. “Yes we are, it’s fantastic! We hardly leave the county, there’s just so much to do," said Derek.The couple moved here from New Mexico, and for nine years Derek's colon cancer seemed to be behind them. “I won’t say cancer-free, but I didn’t have any symptoms for years, until last May, whenever I came in for a checkup, and they discovered cancer again," said Derek.It was stage IV metastatic colon cancer.“It’s a lot. It’s a tough diagnosis, it’s really difficult to live through.”After three months of aggressive chemotherapy, Ruff's condition only got worse. His journey brought him to UC San Diego Health's Moores Cancer for a clinical trial, which unfortunately did not work. But he Ruff became a candidate for another trial involving natural killer cells created from stem cells.“These are patients who don’t have a lot of good options in terms of chemotherapy or immunotherapy," said Dr. Sandip Patel, a medical oncologist who is leading the trial at UCSD. Decades of research on natural killer cells have culminated in the new cancer treatment being developed by San Diego-based Fate Therapeutics.Fate is the first to mass produce cancer-killing cells from a type of stem cell called a human-induced pluripotent stem cell (iPSC). "The concept of utilizing the stem cells that are within us, within our blood factory, within our blood marrow, to create a master bank of cells that we can utilize to program in different ways to fight cancer with cellular immunotherapy."The off-the-shelf, iPSC-derived natural killer cell cancer immunotherapy received U.S. Food and Drug Administration approval to move into clinical trials in November 2018. Ruff is the first person in the world to receive the treatment and got his first dose in February.“Being the first is exciting but it was less so hearing that you have stage iv cancer and you don’t have much of a future, and now I feel hopeful, again," said Ruff.While it's too early to tell if the treatment is working, researchers are hopeful this treatment will one day help many cancer patients. 2212

SAN DIEGO (KGTV) -- Among being big, bold and beautiful, the Torrey Pine tree could also be the solution when it comes to helping with the world's water crisis."As a child we would go hiking there [Torrey Pines] every single weekend and see how there were giant puddles under the tree."And those puddles gave Cambridge High senior, Emily Tianshi, her "a-ha" moment."When Torrey Pines are that big that means they're confident they can get enough moisture soaked in through the atmospheric moisture harvesting, and they don't mind if there's a little bit more evaporation," Emily said.She spent years studying the water retaining tree, trying to mimic it's pines that bring water in and pour it out."Really late at night I would bring my prototype out then put it there and hopefully capture some fog, then go back early to see if anything happened."Her patent pending prototype recently gained national recognition from the Water Environmental Federation."It was really exciting because it showed me it has a lot of potential within the water sector," Emily described.With it, she wanted to one day help areas facing drought."Investigators estimated that if they captured just 4% of the moisture in Chile, it would be enough to cover the nation's driest areas to supply everything."She's also created a campaign with her brother called Clearwater Innovation with two goals in mind."First and foremost to spread awareness about the water crisis and secondly to encourage kids to use their creativity to solve the problem and innovate out of their comfort zone. The resources are right there, people just have to learn to use it just like the Torrey Pine tree." 1668

SAN DIEGO (KGTV) — A San Diego student has been named among those killed when an international flight bound for Ukraine crashed in Iran.Sara Saadat was a student at Alliant International University in Scripps Ranch. She was a passenger on Ukraine International Airlines Flight PS752, according to the school.In a statement to 10News, Saadat was visiting family in Iran and was heading back to San Diego to begin the spring 2020 semester. She was enrolled in the university's clinical psychology program."We extend our deepest sympathies to family and friends of Alliant Student Sara Saadat. Sara was a passenger on Ukraine International Airlines Flight PS752 that crashed in Iran. It appears that Sara was visiting family in Iran and was on her way back to San Diego to begin our spring 2020 term in our PsyD in Clinical Psychology program," the school's statement read. "We know that the entire Alliant community is affected when tragedy strikes any one of us, and we are here to provide support during these trying times."RELATED: Iran says it "unintentionally" struck down Ukrainian jetlinerSaadat's sister, Saba, and mother were also among the 176 passengers on board that were killed. "The Alliant community is still processing the news and many of us are still in shock but overall it's grief and sympathy for the family and friends of [Saadat]," said Amber Eckert, vice president of student affairs. "[Saadat] was a student in our doctorate program in clinical psychology. It's a cohort based program that means [Saadat] will stay with the same group of students ... Very tight knit group of students, they develop life long friendships."The campus is providing on-site support from counselors from the school's student assistance program.Reyaan Shuaib, a close friend of Saadat's, told 10News she was "the sweetest person I'd ever known.""She had an amazing way to speak to people, to listen to people," said Shuaib, noting her natural talent for wanting to be a psychologist."She was the first person who got me to really open up. I’ve never been so close to someone that I was with her," Shuaib revealed.She said the University of Alberta, where Saadat had graduated from, is also offering counseling for those who are grieving.RELATED: Video suggests a missile struck plane in Iran bound for UkraineThe flight bound for Ukraine crashed minutes after taking off from Tehran, Iran, this week. CNN reported among those killed on the flight were 82 Iranians, 63 Canadians, 11 Ukrainians, 10 Swedes, four Afghans, three Germans and three British nationals.The crash came hours after Iran launched a ballistic missile attack on Iraqi bases housing U.S. military. The attack was in response to a US rocket attack that killed Iranian General Qassem Soleimani last week.RELATED: Ukrainian airplane crashes near Iran's capital, killing all 176 passengersWhile Iran has denied responsibility for the crash, Canadian Prime Minister Justin Trudeau said intelligence agencies have concluded an Iranian missile caused the plane crash.“We have intelligence from multiple sources, including our allies and our own intelligence. The evidence indicates that the plane was shot down by an Iranian surface-to-air missile. This may well have been unintentional,” Trudeau told the media.Secretary of State Mike Pompeo said Friday the U.S. believes Iran shot down the plane, adding that the U.S. will take "appropriate action" in response to the crash.President Donald Trump told reporters Thursday that he has "suspicions" about the crash as well."I have my suspicions," Trump told reporters. "It was flying in a pretty rough neighborhood and somebody could have made a mistake." 3675

SAN DIEGO (KGTV) -- A San Diego Marine is setting out to accomplish something few have, climbing the continent's highest peaks and running a marathon on each one.Major Patrick Holcomb is calling it the 7&7 Challenge.“It’s not really official because up until this point only two people have done it," said Holcomb, who's been in the Marine Corps for 18 years.Holcomb will rely on his rigorous training and gear as he completes the mission.He's already run five marathons on five continents and has climbed three peaks.“Every country you go to you get to experience people and culture, there are a lot of differences around the world," said Holcomb. "What’s been shocking for me is realizing, how much at the end of the day, people are all the same."He plans to use his personal mission for good, teaming up with a nonprofit that helps veterans suffering from PTSD or traumatic brain injuries.Holcomb plans to start fundraising during the final leg of the challenge, Mount Everest in 2022.He's currently based at Marine Corps Air Station Miramar. 1057

San Diego (KGTV) – A woman was driving southbound on 47th Street when she lost control and crashed into two parked trucks Sunday morning, according to the San Diego Police Department.One passenger, who was asleep in the backseat and not wearing a seatbelt, was taken to the hospital with a life-threatening brain injury.The other passenger said he was having chest pain, but is expected to be okay.Officers said the driver ran away.They did not know if drugs or alcohol played a role in the accident.Police asked anyone with information to call Crime Stoppers at 888-580-8477. 604

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