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WASHINGTON, June 6 (Xinhua) -- Women who have higher levels of the appetite-controlling hormone leptin have fewer symptoms of depression, and this apparent inverse relationship is not related to body mass index (BMI), a new study finds. The results were presented Monday at The Endocrine Society's 93rd Annual Meeting in Boston, the United States."Animal data suggest that leptin may reduce anxiety and improve depression. Our study in women suggests that leptin may indeed have antidepressant qualities," said the study's lead author, Elizabeth Lawson, of Massachusetts General Hospital and Harvard Medical School in Boston.Leptin, the product of fat cells, signals satiety, or fullness. It is low in thin women and high in obese women, according to Lawson. She also said there is an increased prevalence of anxiety and depression in certain conditions in which leptin levels are typically low. These include the eating disorder anorexia nervosa, in which there is abnormally low weight and body fat, and functional hypothalamic amenorrhea, in which women have stopped menstruating despite having normal weight."It is unknown whether low leptin levels contribute to the development of mood disorders in these women," Lawson said.She and her co-workers studied the relationship between leptin levels and symptoms of anxiety and depression in 64 women. Fifteen of the women had anorexia nervosa, 12 were normal weight with hypothalamic amenorrhea, 20 were normal weight and in good health, and 17 were overweight or obese but still healthy.All subjects were asked questions to assess symptoms of depression and anxiety, with high scores indicating more symptoms. Besides measuring leptin levels in the blood, the researchers assessed the women's BMI, a measure of weight for height.The relationship between leptin and depression symptoms was independent of BMI. This finding indicates that leptin may mediate symptoms of depression and that this effect is not a function of low weight, Lawson said."Further research administering leptin to humans will be important in understanding whether this hormone has a potential role in the treatment of depression," she said.
BEIJING, Aug. 12 (Xinhuanet) -- Engineers at the University of Illinois have unveiled novel, skin-mounted electronics whose circuitry bends, wrinkles, and even stretches with skin, according to media reports quoting the Science Friday.The device platform includes electronic components, medical diagnostics, communications, and human-machine interfacing on a patch so thin and durable that it can be mounted to skin much like a temporary tattoo, the jounral described.What's more, the engineers demonstrated the invention across a wider range of components, including LEDs, transistors, wireless antennas, sensors, and conductive coils and solar cells for power."We threw everything in our bag of tricks onto that platform, and then added a few other new ideas on top of those to show that we could make it work," said engineering professor John A. Rogers in a news release.

WASHINGTON, July 15 (Xinhua) -- Researchers at Mount Sinai School of Medicine have found that grape seed polyphenols -- a natural antioxidant -- may help prevent the development or delay the progression of Alzheimer's disease.The research, led by Giulio Pasinetti, was published online Friday in the Journal of Alzheimer's Disease, which causes brain changes that gradually get worse.This is the first study to evaluate the ability of grape- derived polyphenols to prevent the generation of a specific form of amyloid (A) peptide, a substance in the brain long known to cause the neurotoxicity associated with Alzheimer's disease.In partnership with a team at the University of Minnesota, Pasinetti and collaborators administered grape seed polyphenolic extracts to mice genetically determined to develop memory deficits and A neurotoxins similar to those found in Alzheimer's disease. They found that the brain content of the A*56, a specific form of A previously implicated in the promotion of Alzheimer's disease memory loss, was substantially reduced after treatment.Previous studies suggest that increased consumption of grape- derived polyphenols, whose content, for example, is very high in red wine, may protect against cognitive decline in Alzheimer's. This new finding corroborates those theories."Since naturally occurring polyphenols are also generally commercially available as nutritional supplements and have negligible adverse events even after prolonged periods of treatment, this new finding holds significant promise as a preventive method or treatment, and is being tested in translational studies in Alzheimer's disease patients," said Pasinetti.In Alzheimer's disease, brain cells degenerate and die, causing a steady decline in memory and mental function.
BEIJING, Sept. 26 (Xinhuanet) -- Although it is home to traditional Chinese medicine (TCM), China must do much more to improve its academic research capacity for acupuncture, a form of TCM, to take the lead worldwide on both the academic and clinical sides.At present, among all academic theses on acupuncture indexed by the Science Citation Index (SCI), a leading world thesis index system, only 5 percent are from the Chinese mainland, according to Wang Linpeng, the director of the acupuncture and moxibustion center of the Beijing Hospital of Traditional Chinese Medicine, which is affiliated with the Capital Medical University.Although Chinese acupuncturists absolutely excel worldwide in clinical practice, "they are not as good as their foreign peers in academic capacity, particularly Western-style research methods and lab experiment design," he told China Daily on Friday during the 2011 International Symposium on Acupuncture. A patient suffering from facial paralysis receives acupuncture treatment at a hospital in Nanjing, the capital of Jiangsu province, on Dec 6, 2010.Studies by TCM practitioners - including acupuncturists - largely focus on their area of specialization, and few are in line with global interest in the medical science that has been proven effective over thousands of years, he said."Chinese TCM practitioners are very good at treating conditions, but they are clumsy at showing how and why it really works in an internationally accepted 'language' and 'manner'," said Gao Sihua, chancellor of the Beijing University of Chinese Medicine."It's especially true in TCM circles, where few Chinese practitioners would regularly follow international academic articles and research trends," Wang said.Measured by the number of articles on acupuncture indexed by SCI, the US and European countries lead globally, he said.
TOKYO, Sept. 23 (Xinhua) -- Japan's H-2A rocket carrying a new information gathering satellite was launched at the Tanegashima Space Center in Kagoshima Prefecture on Friday, local media reported.Japan has already introduced three information-gathering satellites in the wake of a missile launch by Democratic People's Republic of Korea, and the latest one will replace the No. 2 satellite which has passed its use-by date, Kydo News said.Japan's H-2A rocket lifts off from the launchiung pad at the Tanegashima space centre in Kagoshima prefecture, Japan's southern island of Kyushu on September 23, 2011. Japan launched a new spy satellite into orbit September 23, officials saidThe development cost of the fourth satellite has reached 35.9 billion yen and its launch expenses have come to 10.4 billion yen, according to the government.The Japan Aerospace Exploration Agency and Mitsubishi Heavy Industries Ltd. were forced to put off the launch three times during the past four weeks due to the approach of a powerful typhoon and discovery of a system glitch. The rocket was initially scheduled to be sent into orbit on Aug. 28.
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