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LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.
BEIJING, June 21 (Xinhua) -- China will launch a new icebreaker for use during an upcoming 2013 polar expedition, a senior oceanic official said on Tuesday.Both the new icebreaker and Xuelong ("Snow Dragon"), an icebreaker that operated in Antarctica, will form an Arctic-Antarctic maritime research team."China will have at least two icebreakers concurrently operating at both the north and south poles," Chen Lianzeng, deputy director of the State Oceanic Administration, told a national conference on polar research, which has been the first since 1984 when the country started expeditions in polar regions.The new icebreaker will boast facilities that will allow it to research the oceanic environment, integrate data for real-time oceanic monitoring, deploy and retrieve detectors and conduct aerial studies using helicopters, Chen said.The two icebreakers will conduct expeditions in polar regions for more than 200 days annually, he said.Fixed-wing aircraft will also be added to the expedition team before 2015, allowing researchers to be transported between China's Zhongshan and Kunlun research stations and Antarctica's Grove Mountains.The Kunlun station went into operation in early 2009 as the first Chinese research station on Antarctica's inland. The Zhongshan station, established in 1989, now serves as a supply base for the Kunlun station.A written comment by Vice Premier Li Keqiang sent to the conference said the polar research, a magnificent feat of the mankind, has great significance for China's oceanic work and sustainable development."Over the past two decades, China's polar research made great achievements and became influential globally," Li said.Li encouraged Chinese scientists to actively participate in international exchanges and cooperation, safeguard national interests and contribute to the peaceful use of polar regions.Since the early 1980s, China has sent 27 Antarctic expedition teams and completed four research missions to the Arctic Ocean.Besides the Xuelong icebreaker, China has built three Antarctic stations -- Changcheng (Great Wall), Zhongshan and Kunlun -- and one Arctic station -- Huanghe (Yellow River) Station.

VIENNA, Sept. 9 (Xinhua) -- The three-day Traditional Chinese Medicine (TCM) exhibition opened Friday in the Flower Garden Hirschstetten in Vienna, with the aim to introduce traditional Chinese medicine to the Austrians and to arouse their interest in the culture of Chinese medicine.Holding for the second time, the exhibition this year have attracted more visitors to take part in the health talks on traditional Chinese medicine, read or buy books around the theme of traditional Chinese medicine. Some visitors enthusiastically tried Chinese diet therapy prepared by the organizers.In recent years, traditional Chinese medicine has been increasingly recognized and accepted in Austria. It has already not only entered into the classroom but also into the hospital and clinic.Some private health insurance companies in Austria have started to include the treatment by traditional Chinese medicine into their insuring categories. Chinese patent drugs are already available in many pharmacies in Austria.But in general, traditional Chinese medicine still faces many limits in Austria, which hasn't been involved into the public health insurance system. Some Austrians still have doubts of Chinese medicine, in particular the medicinal herb drugs. All these have restricted the development of traditional Chinese medicine here.Currently, major clinics of traditional Chinese medicine carry out only acupuncture and moxibustion, massage and other health-care physical therapy.Richard Schmerker, a doctor of traditional Chinese medicine in Austria, told reporters that the development of traditional Chinese medicine here still faces many challenges and the biggest one is the shortage of effective propaganda and popularization.But he expressed his full confidence about the future of traditional Chinese medicine in Austria. He said, the uniqueness of finding the root cause of diseases and laying the axe to the root will make it be accepted by more and more Austrians.
BEIJING, Sept. 6 (Xinhuanet) -- The amount of space junks floating in Earth's orbit has reached a critical level, warned scientists.The future space missions may become too dangerous to fly for a risk of colliding with space junks, said a report released recently by the U.S. National Research Council (NRC).The kinds of space junks range from huge, the report said, there are thousands of discarded satellites and rocket boosters and countless tiny pieces of daily gabages from space missions.The debris are traveling in orbit at 17,500mph, at such a speed even a tiny clash can destroy a spacecraft.The NRC recommended that NASA should launch a plan to clean up the floating debris and called on other major space nations' cooperation."The current space environment is growing increasingly hazardous to spacecraft and astronauts," said Kessler, an ex-NASA researcher, "NASA needs to determine the best path forward for tackling the multifaceted problems caused by meteoroids and orbital debris that put human and robotic space operations at risk."
BEIJING, Aug. 12 (Xinhuanet) -- Engineers at the University of Illinois have unveiled novel, skin-mounted electronics whose circuitry bends, wrinkles, and even stretches with skin, according to media reports quoting the Science Friday.The device platform includes electronic components, medical diagnostics, communications, and human-machine interfacing on a patch so thin and durable that it can be mounted to skin much like a temporary tattoo, the jounral described.What's more, the engineers demonstrated the invention across a wider range of components, including LEDs, transistors, wireless antennas, sensors, and conductive coils and solar cells for power."We threw everything in our bag of tricks onto that platform, and then added a few other new ideas on top of those to show that we could make it work," said engineering professor John A. Rogers in a news release.
来源:资阳报