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LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.
BEIJING, July 17 (Xinhua) -- Iraqi Prime Minister Nouri al-Maliki arrived in Beijing Sunday night for his first official visit to China as a guest of his Chinese counterpart Wen Jiabao.During al-Maliki's stay in China from Sunday to Thursday, President Hu Jintao will meet with him, and Premier Wen will hold talks with the Iraqi prime minister, Chinese Foreign Ministry spokesman Hong Lei said earlier.China and Iraq share a traditional friendship, Hong said, adding that the two countries have witnessed smooth development of bilateral relations, steadily growing economic cooperation and increasing cultural exchanges."China is ready to work with the international community and to continue to provide assistance for the Iraqi people to improve their livelihoods," said the spokesman.
BEIJING, June 28 (Xinhuanet) -- The figure of adults with diabetes has risen to 347 million worldwide, which is more than doubled in the past three decades, according to a study published in the British journal Lancet.The study, which analyzed data compiled from 2.7 million participants aged 25 and over from across the world, shows approximately 138 million in China have diabetes, and 36 million in the United States.Among high-income countries, diabetes rates were the highest in the U.S., Greenland, Malta, New Zealand, and Spain. The Netherlands, Austria, and France boasted the lowest rates, suggested the study published online by The Lancet journal on June 25.Majid Ezzati, a lead author of the study, said on Reuters: “Diabetes is becoming more common almost everywhere in the world.”Danaei added: “Unless we develop better programs for detecting people with elevated blood sugar and helping them to improve their diet and physical activity and control their weight, diabetes will inevitably continue to impose a major burden on health systems around the world.”
MOSCOW, June 27 (Xinhua) -- Russia successfully launched a Cosmos class military satellite on Monday, said spokesman of the Russian Space Forces Alexei Zolotukhin.A Soyuz-U carrier rocket carrying the military satellite blasted off from the Plesetsk Plesetsk space center in northern Russia at 20:00 Moscow time (1600 GMT), Zolotukhin said."The rocket put the Cosmos series military satellite into the designated orbit at 20:08 Moscow time (1608 GMT)," he added.The spokesman also said the launch of the Soyuz-U carrier rocket "was the first time for this type of rockets" in this year.The launch carried out by a team from the Russian Space Forces was supervised by Space Forces Commander Oleg Ostapenko.The satellite, Cosmos-2472, is a new member to a Russian network of about 60-70 military reconnaissance satellites.
SAN FRANCISCO, Sept. 2 (Xinhua) -- A late-season potato blight has been detected on farms in Alaska, only the fourth time the disease appear in the U.S. state since 1995, local media reported on Friday.The disease was found this week in the fields of potato producers in cities of Delta Junction and Palmer, according to the Fairbanks Daily News-Miner, Alaska's second largest daily newspaper.Farmers in both fields are working to prevent the spread of the blight, a fungus-like disease that can kill plants in the field or cause potatoes to rot in storage, the newspaper reported.Growers have been asked to kill all affected plants within 100 feet, and plant samples from both sites will be examined to identify what type of late blight is involved.Experts said that blight can be controlled through the use of fungicides, but the cool, damp weather this summer in the areas has created an ideal environment for the disease to spread.Although Alaska's potato crop is tiny compared to other U.S. states, it has been viewed as a possible global source of seed potatoes in recent years because it is largely free of disease.A local university has explored partnerships with Chinese growers to export certified seed potatoes, noted the Fairbanks Daily News-Miner report.