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Dr. Anthony Fauci delivered more good news regarding a potential coronavirus vaccine, indicating some Americans could begin getting vaccinated by the end of this month.During an interview with CNN’s Wolf Blitzer, Fauci, the director of the National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases, said it’s possible a vaccine could begin reaching some Americans by the end of the month, but was confident some would begin getting vaccinated by the end of the year.Fauci’s declaration came on the same day Pfizer said that its Phase 3 vaccine candidate was showing an effectiveness of over 90%. Fauci said the announcement was promising, but a few more questions need to be addressed before it is given approval. Fauci said that things like the vaccine’s durability and effect on the elderly are among concerns that still need to be tackled.“We may have doses that we’re able to give to people by the end of November, beginning of December,” Fauci told CNN’s Blitzer. “Now you have to go through the hoops of making sure all of the I’s are dotted and the T’s are crossed about the safety and regulatory aspects of it, but we would be giving vaccine, very likely, by the end of this year. That is good news.”Last month, the FDA put into place guidelines on approving a vaccine, which was more restrictive than what the White House had hoped for. The FDA noted that a vaccine candidate must be at least 50% effective. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.“In addition to outlining our expectations for vaccine sponsors, we also hope the agency's guidance on COVID-19 vaccines helps the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy for any vaccine that is authorized or approved,” Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research, said.While it is possible some will begin getting vaccinated in the coming weeks or months, questions remain on how soon a majority of the country will have the opportunity to become vaccinated. The first Americans slated to become vaccinated will be health care workers and people with a high risk of coronavirus complications, such as the elderly and those living in assisted living facilities, according to an NPR report.Given that Pfizer’s vaccine candidate is showing a high level of effectiveness, Fauci called the development “extraordinary.”"We know there's light at the end of the tunnel, but that doesn't mean that we're going to give up the important public health measures that we continually still have to do every single day,” Fauci said.While there is urgency for both public health and economic reasons for a vaccine, some experts have expressed concern over the speed of a vaccine and whether the expedited timeline is long enough to demonstrate efficacy.Even though a vaccine could be ready by year’s end, trials will be expected to continue for over a year to monitor for possible side effects.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.”Pfizer said based on current projections, it expects to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021. 3823

EDGEWOOD, Kentucky — A St. Elizabeth Healthcare thoracic surgeon is inviting the world to witness a complex lung cancer surgery via Facebook.Kentucky has the highest rate of lung cancer in the country, and Dr. Royce Calhoun is using the surgery as an educational experience by talking to viewers about lung cancer and what it takes to treat patients. 358

Dr. Anthony Fauci, the nation's top infectious disease expert, called for the U.S. to "double down" on what he called "common-sense" public health measures on Monday as the country faces a critical juncture amid the COVID-19 pandemic.After enormous surges in cases in the spring and summer, the U.S. was able to flatten the curve a bit in early September. According to Johns Hopkins, the U.S. dropped to a low point of about 34,000 new daily cases of COVID-19, down from a high of about 70,000 new cases in July.However, case rates have increased gradually in recent weeks, and Fauci warned that Americans need to take public health measures seriously as cold weather forces many indoors, adding that the country is "not in a good place" ahead of winter."(Some states) are starting to show upticks in cases and even some increase in hospitalizations in some states," Fauci said Monday during an appearance on ABC's Good Morning America. "You don't want to be in a position like that as the weather starts getting cold."Fauci added that despite the increase in cases, he did not believe the U.S. needed to go into another total lockdown similar to the one that took place in March and April."I would really like to not go there because it causes so many collateral issues and problems," Fauci said. "...obviously, if things really explode, you'd have to consider that. But we want to do everything we possibly can to avoid an absolute shutdown. In other words, get the cases under control by the common-sense types of things that we've been talking about all along, those public health measures."However, Fauci said he was "concerned" by Florida's decision to reopen bars and restaurants. On Friday, Florida Gov. Ron DeSantis moved the state into "Phase 3" of its reopening plan, meaning that restaurants, bars and hotels can operate at full capacity. Local governments are also unable to restrict a business' operating capacity unless granted permission by the state.Fauci said he was specifically troubled by the state's reopening of bars."That is very concerning to me," Fauci said. "We have always said that — myself and Dr. Deborah Birx, who is the coordinator of the task force — that that is something that we really need to be careful about, because when you're dealing with community spread, and you have the type of congregate setting where people get together, particularly without masks, you're really asking for trouble."In the past, Fauci has advocated for five common-sense public health measures that all Americans should take amid the pandemic: Wearing masks, avoiding crowds, keeping six feet apart from others, constant hand washing and opting for outdoor activities over indoor activities. He says if the U.S. continues to follow those guidelines, the country can continue to open up the economy."If you (open the economy) in a prudent way — in a prudent way means focus on things that are important — you can open businesses, you can do things like that," Fauci said. "But when you start opening up bars without masks or congregate settings where people are indoors without masks, that's asking for trouble." 3136

During the start of the COVID-19 pandemic, many couples turned to Zoom and other virtual video platforms so they could still get married in front of loved ones. But as the pandemic continues, a lot of couples are now back to holding weddings in-person. With a little bit of distance between guests."I definitely think it’s going to be a thought on everybody’s mind whether: do you keep smaller numbers or do you have the large numbers you originally wanted and you just space the chairs? Do you have to have more tables and more people per table?" said Braden Sutton, a wedding planner, day-of coordinator and ordained minister with JBS Weddings and Events in Georgia. He, like other wedding planners across the country, saw soon-to-be wed couples panic when the pandemic first erupted in the spring."Of course they want the big wedding they planned but they don't know what to do because they don't want to cut people off of the list and they don't want to hurt anybody’s feelings," said Sutton.Six months into the pandemic, Sutton says more couples are turning to socially-distanced weddings, making accommodations at their venues and sometimes shortening their guest lists to still have an in-person celebration as safely as possible. "Because we’ve all seen a few things on social media about large numbers of COVID cases happening at weddings and other gatherings, nobody wants that to be their wedding. Definitely it's possible, just play it smart," said Sutton.Courtney Saxon and Kayla Zachery began planning their Georgia wedding nearly a year ago. "And honestly, in the beginning I think we both were like, 'Oh, everything will be fine by November we’re not going to have to worry about it,'" said Saxon. They soon realized, if they wanted to keep their wedding date, they'd need to make a few adjustments. Chairs at the ceremony will be spaced and fewer people will be seated at each table."Ideally what will happen is everyone will sit as a family unit. So if you live together, of course you're already around one another. We're just trying to keep everyone essentially around people they came with," said Saxon.They'll also have hand sanitizing stations at food tables and all entrances, plus a video live stream of the event for those guests who can't attend in person. While the wedding won't look exactly how they envisioned, the two have a positive outlook for their special day. "To me, the most important thing is that at the end of the day I get to marry my best friend. That's really all I care about. It doesn't matter if everything goes exactly as I hoped or we planned because no matter if you get married in a pandemic or not, things are bound and determined to go wrong," said Saxon."What do they have to do to make sure they're safe, guests are safe and another part is just the venue what they require," said Sutton. Sutton is also planning his own wedding which is supposed to take place in March. He believes most couples will be planning socially-distanced weddings through the end of 2021. 3029

EL CAJON (KGTV) -- A group firefighters battling a house fire in El Cajon rescued two of their own from under burning debris Tuesday morning.Heartland Fire & Rescue crews were called to a two-story structure fire in the 1300 block of Helix View Drive around 3 a.m. and discovered a home fully engulfed with flames reaching as high as 50-feet.As firefighters worked to extinguish the blaze, a burning section of the home collapsed trapping two of them. Both were quickly pulled out from under the rubble.One of the firefighters was treated and transported to a nearby hospital with unknown injuries. The condition of the second firefighter is unknown at this time.The homeowner told 10News that all family members were able to evacuate the burning home safely. The fire has since been extinguished but crews remain on scene. 837