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WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.
LOS ANGELES, April 12 (Xinhua) -- With the help of NASA Telescopes, astronomers have uncovered one of the youngest galaxies in the distant universe, with stars that formed 13.5 billion years ago, the Jet Propulsion Laboratory (JPL) announced on Tuesday.The finding addresses questions about when the first galaxies arose, and how the early universe evolved, JPL noted in a press release.Infrared data from both the Hubble Space Telescope and the post- coolant, or "warm," phase of NASA's Spitzer Space Telescope mission revealed that the galaxy's stars are quite mature, which means they must have formed when the universe was just a toddler, said JPL in Pasadena, Los Angeles.This challenges theories of how soon galaxies formed in the first years of the universe and could even help solve the mystery of how the hydrogen fog that filled the early universe was cleared, according to astronomers involved in the study.This galaxy is not the most distant ever observed, but it is one of the youngest to be observed with such clarity, JPL said.Normally, galaxies like this one are extremely faint and difficult to study, but, in this case, nature has provided the astronomers with a cosmic magnifying glass, JPL said.The galaxy's image is being magnified by the gravity of a massive cluster of galaxies parked in front of it, making it appear 11 times brighter. This phenomenon is called gravitational lensing."Without this big lens in space, we could not study galaxies this faint with currently available observing facilities," said Eiichi Egami of the University of Arizona in Tucson. "Thanks to nature, we have this great opportunity to see our universe as it was eons ago."The findings may help explain how the early universe became " reionized," according to JPL."Seeing a galaxy as it appeared near the beginning of the universe is an awe-inspiring feat enabled by innovative technology and the fortuitous effect of gravitational lensing," Jon Morse, NASA's Astrophysics Division director at the agency's headquarters in Washington, said in the release."Observations like this open a window across space and time, but more importantly, they inspire future work to one day peer at the stars that lit up the universe following the big bang."

JERUSALEM, May 2 (Xinhua) -- Traditional farming may have found an ally on the Internet, via an Israeli "cloud-based" software system that enables farmers to get professional information and tips from colleagues worldwide.And IBM is interested in what they have to say.Agriculture Knowledge On-Line (AKOL) says its Internet-based system can aid global agriculture by utilizing the collective knowledge of kibbutzim (communal farms in Israel) and other agricultural experts, to offer small farmers personalized solutions to improve dairy output and crop production, and better prevent droughts.Owned by Kibbutz Bror Hayil in southern Israel, the software house has recently signed a cooperation and development agreement with IBM to manage access and technology issues."What we do here is like a bank of information and IBM provides the special tools for the end users," AKOL's CEO Roni Shani told Xinhua, "and you can do what we call 'agricultural market.'""For example, if someone in Australia needs advice on how to grow their crops better, they can just ask our advice or search through our database to find the best product for the country they 're growing the crops in," Shani said."Let's say someone in India, a small farmer, has a problem with their crop or chickens," Shani explained, noting that "it's usually very expensive and time consuming to get someone to come and check what is wrong."But, for a monthly fee, a basic subscription service enables the end user to access the software database, which allows "the farmer to just look at the pictures and pick the one that will explain what the disease or problem is and offer a solution, and if it is available in their country."AKOL claims about 1,000 customers over the globe."We just started developing it for use outside of the kibbutz with IBM's help," Shani said, "and we are developing it also in other parts of the world, like China. Right now we're cooperating with the Chinese government to help milk producers get the most out of their milking systems."Israel is one of the leading countries in milk production, with each cow yielding around 12,000 liters of milk a year on average. Two Chinese provinces plan to use AKOL's milking control system, in order to better manage their herds and equipment and increase milk production."And this is just the beginning," Shani explained, "because we are also working with other developing countries. This software will help millions of small farmers in rural or impoverished areas, that will be able to get advice and benefit from other farmers' experience on the spot and at a very affordable rate."
BEIJING, Feb. 26 (Xinhua) -- Zhu Guangya, who contributed to the development of China's first atom and hydrogen bombs, died Saturday at age 87.Zhu was a senior academician at the Chinese Academy of Sciences and the Chinese Academy of Engineering. He served as vice chairman of the National Committee of the Chinese People's Political Consultative Conference, China's top political advisory body, between 1994 and 2003.Born in central China's Yichang city, Zhu obtained a PhD in nuclear physics from the University of Michigan in 1950. That year he returned to China. He joined the Communist Party of China in 1956.
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