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JULIAN (CNS) - A motorcyclist was killed in a crash near Julian on Saturday.California Highway Patrol officers headed to state Route 79 near Sunrise Highway about 1:50 p.m. for a report that a Toyota 4Runner had struck a motorcycle and pinned the rider underneath the vehicle, according to a CHP incident log.The motorcyclist was pronounced dead at the scene, according to Cal Fire San Diego. No identifying information on the victim was available.One-way traffic control was in place while authorities investigated and worked to clean up the crash, according to the CHP. 579

KANSAS CITY, Mo. (AP) — President Donald Trump said Friday that Congress should provide all the money he wants for his promised U.S.-Mexico border wall, and he called illegal immigration a "threat to the well-being of every American community."Trump spoke hours after signing a short-term spending bill that covers key government departments for two more weeks, until Dec. 21, setting up a pre-Christmas showdown over the wall.The president wants the next spending package to include at least billion for the proposed wall. House Democratic leader Nancy Pelosi of California rejected that a day earlier.At an appearance in Kansas City, Missouri, Trump accused Democrats of playing a political game, and said it was one that he ultimately would win."Congress must fully fund border security in the year-ending funding bill," Trump said as he helped close the 2018 Project Safe Neighborhoods law enforcement conference, which was sponsored by the Justice Department. "We have to get this done.""They're playing games," he said of Democrats. "They're playing political games. I actually think the politics of what they're doing is very bad for them. We're going to very soon find out. Maybe I'm not right. But usually I'm right."He also said money for a program that encourages federal, state and local authorities to collaborate on crime-fighting strategies was increased by million this year. The president said he will ask Congress for more money next year, but didn't say how much.Trump said his administration is giving law enforcement officials the resources they need to do their jobs. He said there are more than 200 new violent crime prosecutors nationwide and cities have access to 0 million worth of surplus military equipment.Introducing Trump was acting Attorney General Matthew Whitaker. Trump announced before leaving Washington that he planned to nominate William Barr, who was attorney general under President George H.W. Bush, to again lead the Justice Department.The short-term spending bill avoided a partisan fight that had been expected this week as Washington. It was put on hold for ceremonies honoring Bush, who died Nov. 30.Trump is set to meet Tuesday at the White House with Pelosi and Senate Democratic leader Chuck Schumer of New York. Republicans control the House and Senate now, but Democrats will retake the majority in the House in January after midterm election victories last month.The president said the money he is demanding from Congress would fully pay for Immigration and Customs Enforcement officers, attorneys, detention beds and the border wall, which he said is needed "more than ever."Trump has been agitated by multiple caravans of Central American migrants that have made their way to the U.S.-Mexico border. Several times he has threatened to seal off entry into the U.S. He claims many of the migrants are criminals or individuals unwanted in the U.S."Every American citizen is entitled to a safe community and a secure border," Trump said.___Associated Press writers Zeke Miller and Deb Riechmann in Washington contributed to this report. 3105

Just after Secretary of State Rex Tillerson's sudden firing Tuesday morning, American diplomats at posts spanning the globe were then increasingly surprised -- and in some cases disturbed -- to receive guidance from Washington telling them not to post or retweet the statement from Undersecretary of State Steve Goldstein on how Tillerson was fired by President Donald Trump, according to multiple diplomats who spoke to CNN about the guidance.Goldstein, part of Tillerson's tight inner circle of aides, had released a statement to the press and then tweeted words that he says came from Tillerson himself on his firing: "The secretary did not speak to the President this morning and is unaware of the reason, but he is grateful for the opportunity to serve, and still believes strongly that public service is a noble calling and not to be regretted." 859

LA CRESCENTA, Calif. (AP) — Searchers have found a hiker who has been missing in the mountains north of Los Angeles for a week.Authorities say 73-year-old Eugene Jo was found alive Saturday by one of 11 search-and-rescue crews that have been searching the San Gabriel Mountains for him.Sgt. Greg Taylor with the Los Angeles County Sheriff's department says cellphone coverage is spotty in the mountains, so he has no immediate word on Jo's condition. He says Jo was being transported to a hospital to be examined.Jo was hiking with a group to the 8,000-foot (2,438-meter) summit of Mount Waterman on June 22 when he became separated from them.Taylor said more than 70 people have been searching for him in the mountains. 728

LA JOLLA, Calif. (KGTV) - A researcher at UC San Diego just got a million grant to further his work into nanosponge therapy.Liangfang Zhang, a professor of nanoengineering and bioengineering, has been working on creating macrophage cellular nanosponges, tiny particles covered in white blood cell membranes, to treat sepsis and other diseases."They can be used to bind to the virus and neutralize the virus," Zhang says. "So now the virus would lose the ability to infect the host cells."The nanosponges act as decoys, tricking a disease or virus into binding with them instead of with human cells. While the initial aim is to treat sepsis, Zhang says it has applications to other deadly diseases, including COVID-19."The formulation that we're developing for treatment of Sepsis is the same formulation that you will use with COVID-19," he says.The grant comes from CARB-X, a Boston-based medical philanthropy that specializes in funding research into antibacterial treatments. Zhang says the money will be used for his company, Cellics Therapeutics, to further advance the research into clinical trials, FDA approval, and production of the nanosponge therapy.Steve Chen, president and chief medical officer of Cellics Therapeutics, says he's hopeful they can advance the nanosponges into human trials within two years."We're essentially looking at how this platform can treat not just infectious disease or future pandemics, but you could actually have a lot of applications in any type of autoimmune diseases or any type of inflammatory diseases," says Chen.In an early study published this year, Zhang's research showed the nanosponges were around 90% effective at blocking infections from taking hold.RELATED: UC San Diego researchers testing nanosponges to fight COVID-19Chen says the research and trial period may take too long for the nanosponges to be used during the current coronavirus pandemic. But he's hopeful it will help make the next outbreak less severe."My sincere desire is that we are not going to need this for COVID-19. But I think this does position us very well for any potential future kind of viral outbreak," says Chen.Cellics is also working on a Red Blood Cell version of their nanosponges, which may be ready for human trials within a year. 2283