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SAN DIEGO (AP) — Manny Machado went hitless in his first game with the San Diego Padres and Fernando Tatis Jr. singled twice in his big league debut, a 2-0 opening win over the San Francisco Giants on Thursday.Wil Myers homered off Madison Bumgarner in the start of a new era for the Padres, who popped above .500 for the first time since June 8, 2015.The Padres signaled their intentions to move beyond the rebuilding stage when they signed Machado to a 0 million, 10-year contract early in spring training. They then promoted Tatis Jr., whose father played in the big leagues for parts of 11 seasons, giving fans some hope after years of futility. San Diego hasn't had a winning season since 2010.RELATED: Heading to San Diego Padres Opening Day 2019? Here's what to knowMachado got a standing ovation as he walked to the batter's box for the first time with the Padres. The crowd booed when he took strike one, and the All-Star slugger struck out on three pitches. He struck out on a foul tip his next time up and then grounded into a double play.Tatis Jr. singled to left in his first big league at-bat, bouncing a ball over the glove of diving third baseman Evan Longoria in the second inning. The 20-year-old bunted for a hit his next time up, but was thrown out trying to steal second. Tatis's parents and siblings traveled from the Dominican Republic for the opener.Tatis became the youngest player with a multihit game on opening day since Milwaukee's Robin Yount in 1975.RELATED: Manny Machado signing a home run for Padres ticket, merch sales, StubHub saysMyers, batting in the No. 2 spot, just ahead of Machado, hit a 456-foot drive to right-center off Bumgarner (0-1) with two outs in the third. Myers added an RBI single in the sixth.Left-hander Eric Lauer (1-0), a 23-year-old who was on an opening-day roster for the first time, threw six innings of four-hit ball. Bumgarner (0-1) struck out nine while allowing two runs and five hits in seven innings.RELATED: Brews outside Petco: Breweries to visit before, after the ballgame downtownIt was the beginning of the end for Giants manager Bruce Bochy, who announced in spring training that he will retire at the end of this season, his 25th as a big league manager. He managed the Padres from 1995 until being pushed out after a playoffs loss to St. Louis in 2006. While San Diego hasn't been back to the postseason since, Bochy was snapped up by the Giants and managed them to three World Series titles in five seasons starting in 2010.Kirby Yates pitched the ninth for the save.YOUNG ONEAt 20 years, 85 days, Fernando Tatis Jr. is the youngest Padres player to play on opening day and the youngest to play in a game since Roberto Alomar in 1988. He is the fifth-youngest Padres player ever.UP NEXTGiants: LHP Derek Holland, who was 7-9 with a 3.57 ERA last year, gets the start Friday night.Padres: LHP Joey Lucchesi, 8-9 with a 4.08 ERA as a rookie last year, is scheduled to start the second game of the four-game series. 3000

SAN DIEGO (AP) — A son of one of the founders of the Sinaloa drug cartel has appeared in a U.S. court on trafficking and other charges after he was extradited from Mexico. A lawyer for Ismael "El Mayito Gordo" Zambada-Imperial says he pleaded not guilty to the charges in the federal court in San Diego and his next court hearing is scheduled for Feb. 7. Zambada-Imperial is accused of smuggling large quantities of cocaine and marijuana from Mexico to the United States, as well as the laundering of profits from the illegal drug trade. RELATED: Son of Mexican drug lord Joaquin 'El Chapo' Guzman at center of shootoutHe was arrested in 2014 on weapons charges.Zambada-Imperial's father, Ismael “El Mayo” Zambada Garcia, was reportedly a partner of Joaquin “El Chapo” Guzman. Guzman was extradited to the U.S. and convicted in Brooklyn in February. He's now serving a life sentence in a federal prison in Colorado.Zambada Garcia is reportedly still at large, according to the FBI. 989

SAN DIEGO (CNS) - A 28-year-old man who appeared to suffer some type of medical emergency and passed out after fighting with deputies arresting him at a North County convenience store last week died at a hospital, authorities reported Wednesday.Marco Napoles Rosales of El Monte was pronounced brain-dead Tuesday, six days after his violent encounter with law enforcement personnel, according to sheriff's officials. A ruling on his cause of death remains on hold pending an autopsy.The events that led to Rosales' confrontation with law enforcement personnel began about 4:30 a.m. last Thursday, when a 911 caller reported that he had been acting strangely in a Circle K market on state Route 76 in Fallbrook, seemed to be "under the influence of drugs" and was refusing to leave the business, Lt. Rich Williams said.RELATED: San Diego deputy, suspect hospitalized after violent confrontationEight deputies arrived a short time later, contacted the Los Angeles-area resident and tried to evaluate him, at which point he allegedly became belligerent.During an ensuing struggle, the patrol personnel shocked Rosales with an electric stun gun, and he bit one of them on the hand, Williams said.The deputies were able to get Rosales into restraints after two men who saw what was happening while driving by hurried over and helped subdue him.A short time later, while being taken to a hospital for an examination, the suspect experienced apparent medical distress and lost consciousness.When informed that Rosales was beyond recovery, his family decided to keep him on life support for organ-donation purposes, the lieutenant said. 1636

SAN DIEGO (AP) — California health officials have warned that a severe flu season could overwhelm hospitals that also are dealing with COVID-19. California Secretary of Health and Human Services Dr. Mark Ghaly joined the heads of the state's hospital and medical associations to urge people to get flu vaccines now. Ghaly said while the state has seen progress in recent weeks with a drop in coronavirus cases, officials expect an uptick as the economy continues to open. That makes it critical for hospitals to keep bed space available. Officials said currently hospitals are treating 3,500 confirmed and suspected COVID-19 patients. About 30 percent are in intensive care units. 688

SAN DIEGO (CNS) - A Guatemalan family that alleges they were denied asylum despite facing the continuous threat of harm in their home country and Mexico must be allowed access to legal counsel during proceedings that could force the family to remain in Mexico, according to a San Diego federal judge. 308

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