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While scientists work to come up with a safe and effective COVID-19 vaccine, doctors across the country are watching closely. Many are helping guide their patients in making an informed decision about getting a vaccine."This was indeed a surprise to see that there would vaccines available by the 1st of November. It’s clearly an aspirational goal, because we all would like to see a safe and effective COVID-19 vaccine as soon as possible, but I think testing vaccines to make sure they’re safe and effective is of paramount importance," said Dr. Bali Pulendran, a microbiology and immunology professor at Stanford University.Dr. Pulendran says the process of developing a vaccine involves numerous steps, and scientists are getting closer to the end. Still, it's hard to put an end date on the third and final phase of a vaccine trial. This last phase determines whether the vaccine actually works."The way in which you can assess whether a vaccine works is to see how many of these people acquire the disease or become infected with COVID at some period of time," explained Dr. Pulendran.Phase three divides the trial participants into two groups. One group is given the vaccine, and the other is given a placebo."And then, you calculate the efficacy based on those numbers. So, if there were 200 people affected in the placebo group but there were only 100 people who were infected in the vaccinated group, then the efficacy is 50 percent" said Dr. Pulendran.The third phase is hard to time, as it depends on how quickly some of the trial participants become infected. If they live in areas where COVID-19 infection rates are higher, the phase will be completed faster.But there are some other ways to speed up the vaccine trial.Dr. Darria Long, an emergency room physician and clinical assistant professor at the University of Tennessee-Erlanger, says one way is by doing two of the phases at the same time. Another way is if officials prepare for the manufacturing and logistics side of producing the vaccine during the third phase of the trial."This is what we see the CDC saying is to get ready on the manufacturing and logistics side because even if you come up with the perfect target drug, making sure you can manufacture hundreds of millions and that you have the little glass vials that can keep it at the right temperature, those are all things that can be hang-ups,” said Dr. Long. “So, they're wanting to expedite that process, because the last thing you want is to say is we have the vaccine, but we can’t get it to people.”Dr. Long is already answering her patients' questions as news of a possible COVID-19 vaccine continues to be publicized."I do think a lot of people are wondering about this vaccine and it runs the gamut. There are those that say they really want the vaccine because they see it as this gateway to getting back to life as we know it," said Dr. Long.There are also those who are really concerned about the efficacy and safety of a COVID-19 vaccine. Doctors say a key piece in evaluating a vaccine when it does come out is the data surrounding it."The data that comes out in the public domain: is a particular vaccine efficacious? How effective is it what is the efficacy data? Is a particular vaccine safe? What are the side reactions? And they should talk with their physicians to ask each question. Ask doctors, ‘Could you tell me what the safety part of this vaccine is?" recommended Dr. Pulendran.And above all, doctors and scientists hope politics will stay out of the development of a COVID-19 vaccine in order to ease any concerns or hopes for a vaccine to be available as soon as possible. 3644

When you sit down to do your taxes in the next six months, there are some things you need to know. There'll be a lot of changes to what you can deduct when you file your taxes next year.Elaine Espinola is one of the 150 million Americans who is gearing up to file a tax return under the new law."Sounds like I can't deduct a lot of things that we had been,” Espinola says.Shes right.Tax expert Ed Karl says the tax bill that passed last December is the biggest overhaul to the tax code in over three decades."Nothing of this magnitude since 1986,” Karl explains. 575

White House officials and House Democrats said Friday they’re no closer to a deal with on a stimulus package, a week after extended unemployment benefits expired.While the White House said they believe a compromise can be made on some issues, the two sides remain far apart on funding state and local governments. Many states and municipalities are struggling due to decreased revenues and increased costs amid the pandemic.There is also disagreement among the parties, including Senate Republicans, on unemployment supplements as unemployment figures remain over 10%. From April into July, unemployed workers received an additional 0 unemployment supplement on top of standard unemployment benefits. But many Republicans grumbled that the supplement gave incentive for workers to stay home amid the pandemic.Generally, however, if an employer calls an employee back to work, they're no longer eligible for unemployment benefits.Treasury Secretary Steven Mnuchin told reporters on Capitol Hill Friday that he is going to recommend executive orders addressing student loan payments, evictions and unemployment supplements. Currently, federal student loan payments are frozen into October. Also, protection ended last week on evictions.President Donald Trump told reporters late Friday that he plans on signing the order "by the end of the week." But Trump said he expects there will be legal challenges to his order. Mnuchin and White House Chief of Staff Mark Meadows said that there is broad agreement on some issues, such as funding for schools to safely operate amid the pandemic. Previously, the sides also said there is agreement on providing Americans with ,200 stimulus checks for the second time this year. But Mnuchin and Meadows pointed the finger at House Democrats for not compromising on the unresolved issues.“Just to hear the comments from Senator Schumer and Speaker Pelosi saying they “want a deal” when behind closed doors, their actions do not indicate the same thing,” Meadows said.Meanwhile, Democrats pointed the finger back at the White House for not reaching a compromise.While the White House suggested that it would be okay with a partial stimulus package, Democrats are calling for a more comprehensive bill.“We’re asking them to be fair, to meet us in the middle, not to have a my way or the highway attitude, which they seem to have,” Senate Minority Leader Chuck Schumer said. “We can really get this done, because there are some areas where we didn’t come to an agreement on many things, but we narrowed our differences.”Both the House and Senate have adjourned for the weekend. 2622

When it comes to Christmas decorations, country music star Tim McGraw lives by the expression "go big or go home."On social media, McGraw showed off his impressively tall Christmas tree.In the pictures, McGraw is seen going to great lengths to decorate the tree - using a very tall ladder, using a long pole to move branches, and adjusting the tinsel with one leg in the air.He cheekily captioned the photos with "A: Santa's lead flying reindeer B: wife trying to get rid of me before Christmas." 504

Will the iPhone X change your life for the better and usher you into the future, face first? Or is it just another smartphone with a giant screen and a strange little rectangle on top?We've only had the phone since Monday morning. It's more than the few minutes of hands-on time reporters had when the device was launched, but a day is not enough time to fairly review the iPhone X. It's like deciding if you want to marry someone after one blind date.So while we test, tinker and tap this week, here are some first impressions to whet your appetite, presented as yearbook superlatives: 594

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