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The death toll from a powerful explosion in Beirut Tuesday has reached 100 and is still climbing. At least 4,000 others were injured.While no one knows yet exactly how many people died in the blast, the destruction was so extensive that the shockwave was felt across the city.The blast, which began as a fire in a port warehouse, happened just after 6 p.m. local time.Beirut's emergency services were so overwhelmed that it was up to whoever could help to provide comfort to the injured. Open lots were turned into field hospitals.In an instant, lives were lost and livelihoods were destroyed."The whole house collapsed on us," one woman who survived the blast said.Following the explosion, Michel Haibe visited the site of what used to be his electrical goods store."Forty years," Haibe said. "War, we've seen woes of every kind, but not like this. As if the economic crisis, coronavirus, the revolution weren't enough, this tops them all."Life was already a struggle in Lebanon with its economy in freefall and the coronavirus on the rise. Now, the country's capital must dig out of another tragedy."We got here an hour ago, and as you can see, it's completely and utterly destroyed," bar owner Hadi Shahlawi said. "We've been open since last October and we've been fighting every month with different circumstances — the economic situation. It's catastrophic; what's happening in Lebanon is a catastrophe." 1417

The FDA has ended an emergency use authorization (EUA) order for hydroxychloroquine, saying that the agency has determined that drug is "unlikely to be effective in treating COVID-19."In the announcement, the agency said that the benefits of hydroxychloroquine and a related drug, chloroquine phosphate, "no longer outweigh the known and potential risks for the authorized use."The FDA issued the EUA for the drug in March. In April, the FDA warned that the drug should only be used in hospital settings due to the severe side effects some experienced while taking the drug.Shortly after the coronavirus arrived in the United States, President Donald Trump touted the drug as a potential treatment for the disease. He encouraged those sickened with the virus to take the drugs, saying, "what do you have to lose?"Trump said he took the drug for a few weeks in May as several White House staffers contracted the virus. In an open letter, White House physician Sean Conley said he prescribed the drugs after determining that the "potential benefit from treatment outweighed the relative risks."Earlier this month, a study showed that the drug was likely not effective in treating COVID-19. That study was published just days after a separate study — which determined that people who took the drugs died at a higher rate than those who did not take the drugs — was retracted by three of its authors. 1404

The Dow Jones Industrial Average has nearly made a full comeback from the coronavirus doldrums its faced during the spring.After peaking in February at 29,551, the Dow Jones dropped to 18,591 just a month later. On Tuesday, the Dow closed at 29,420 points for its highest close since February 12.The Dow Jones has been spurred by news that Pfizer’s Phase 3 coronavirus vaccine is showing at 90% effectiveness rating. The news has buoyed stocks from across the spectrum in recent days, including travel, technology and entertainment.After a summer of impressive gains, the Dow leveled off for much of the fall as coronavirus cases began to surge throughout the US. 671

The College Football Playoff semifinal at the Rose Bowl is moving to AT&T Stadium in Arlington, Texas.Bill Hancock, executive director of the College Football Playoff, made the announcement in a statement Saturday night on the eve of the release of the final playoff rankings.The College Football Playoff and Rose Bowl "mutually agreed" to move the game because of the growing number of coronavirus cases in Southern California."We are pleased that parents and loved ones will now be able to see their students play in the game," Hancock said.The move came after several coaches expressed their dismay about possibly traveling to the Rose Bowl to play in a game where players' families wouldn't be allowed.Los Angeles County is under a stay-at-home order that took effect earlier this month. Pasadena, home to the Rose Bowl, has its own public health department but has mostly followed the county's practices during the pandemic.A source told The Associated Press that the Rose Bowl sought an exemption from the state of California to allow families to attend but was denied twice.Hancock said the game will still be played in the mid-afternoon on New Year's Day."We are very grateful to Rose Bowl officials and the city of Pasadena," Hancock said. "They have worked hard to listen to the concerns of the CFP, the teams that might have played there, and their state and government officials. The Tournament of Roses has acted in the best interest of the people who live in Southern California, and we're grateful to Cotton Bowl and AT&T Stadium officials for their ability to make this late switch possible." 1624

The Democratic National Convention featured a video on Tuesday highlighting the friendship between former Senate colleagues John McCain and Joe BidenThe video featured Cindy McCain, Sen. McCain’s widow.“My husband and Vice President Biden enjoyed a 30+ year friendship dating back to before their years serving together in the Senate, so I was honored to accept the invitation from the Biden campaign to participate in a video celebrating their relationship,” Cindy McCain tweeted.The Biden-McCain relationship has been well documented over the years.In 2017, following Sen. McCain’s brain cancer diagnosis, Biden appeared on ABC’s “The View,” which is co-hosted by the senator’s daughter Meghan McCain. The segment was emotional, as Biden discussed how he lost his son Beau in 2015 from the same type of cancer that ultimately killed Sen. McCain.McCain died in August 2018 from brain cancer.The Democratic Party has used the convention to paint Biden as a bipartisan candidate who can attract moderate Republicans. On Night 1 of the convention, Democrats featured former Ohio Gov. John Kasich among other Republicans to display their support for Biden.While McCain was once the standard bearer for the Republican Party, his influence in the party dwindled in his later years. In 2017, shortly after his cancer diagnosis, McCain joined just two other GOP senators in striking down legislation that would have repealed parts of the Affordable Care Act. McCain’s vote drew scorn from Republican leaders including President Donald Trump.The frosty relationship between Trump and McCain became evident following McCain’s death, when he opted in his will not to invite Trump to his funeral, but extended invitations to former Presidents Bill Clinton, George W. Bush and Barack Obama. 1786