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WASHINGTON, June 7 (Xinhua) -- Advanced hepatitis C patients with chronic liver disease may benefit from drinking coffee during treatment, according to a new study published Tuesday in Gastroenterology, the official journal of the American Gastroenterological Association Institute.The study shows that patients who received peginterferon plus ribavirin treatment and who drank three or more cups of coffee per day were two times more likely to respond to treatment than non- drinkers.Among non-drinkers, 46 percent had an early virologic response; 26 percent had no detectable serum hepatitis C virus (HCV) ribonucleic acid at week 20; 22 percent had no detectable serum at week 48; and 11 percent had a sustained virologic response. In contrast, the corresponding proportions for those who drank three or more cups of coffee per day were 73 percent, 52 percent, 49 percent and 26 percent, respectively."Coffee intake has been associated with a lower level of liver enzymes, reduced progression of chronic liver disease and reduced incidence of liver cancer," said Neal Freedman, of the National Cancer Institute and lead author of this study. "Although we observed an independent association between coffee intake and virologic response to treatment, this association needs replication in other studies."Approximately 70 to 80 percent of individuals exposed to HCV become chronically infected. Worldwide, these individuals are estimated to number between 130 and 170 million. Higher coffee consumption has been associated with slower progression of pre- existing liver disease and lower risk of liver cancer. However, the relationship with response to anti-HCV treatment had not been previously evaluated.
SAN FRANCISCO, June 13 (Xinhua) -- Social networking giant Facebook will likely go public in the first quarter of 2012 with a valuation that could top 100 billion U.S. dollars, U.S. media reported on Monday.In a report, CNBC quoted people familiar with the matter as saying that Facebook could submit filing to register its securities with the U.S. Securities and Exchange Commission (SEC) as early as October or November this year.People who are on Wall Street and track this information told the business news television channel that they think the Facebook initial public offering (IPO), if and when it happens could value the company of more than 100 billion dollars.A factor in the company's IPO timing is the SEC's requirement that companies must disclose financial information if they have more than 500 private investors."The company has until the end of April 2012 to disclose their financials, but they may just want to get ahead of that by doing a formal initial public offering, I'm told. And that could happen in the first quarter of the year," said CNBC Wall Street reporter Kate Kelly.Facebook is also facing internal pressure as employees have not been permitted to sell their private shares on the secondary market since last spring. An IPO would make it easier for employees to monetize their shares, said Kelly, citing sources.Facebook shares have been traded in private markets such as Sharepost.com, which puts the social networking company's valuation at 85 billion dollars.Meanwhile, latest data show that Facebook is losing users last month in the United States, Canada and several European countries, indicating that the company could have hit the limits of expansion in its mature markets.
WASHINGTON, July 8 (Xinhua) -- U.S. space shuttle Atlantis lifted off on Friday morning from Kennedy Space Center in Florida, on the 135th and final flight in NASA's shuttle program.The shuttle blasted off at about 11:29 a.m. EDT (1529 GMT) on a tower of flame, NASA TV showed.Before taking flight, shuttle Commander Christopher Ferguson saluted all those who contributed over the years to the shuttle program."The shuttle is always going to be a reflection of what a great nation can do when it dares to be bold and commits to follow through,'' he said. "We're not ending the journey today ... we're completing a chapter of a journey that will never end.''In this photo released by NASA, space shuttle Atlantis lifts off from NASA's Kennedy Space Center in Florida, the United States, July 8, 2011. U.S. space shuttle Atlantis lifted off at about 11:29 a.m. EDT (1529 GMT) on Friday from Kennedy Space Center in Florida, on the 135th and final flight in NASA's shuttle program.Atlantis's primary payload is an Italian-built cargo hauler named Raffaello which is loaded with 8,640 pounds (3,919 kgs) of food, clothing, supplies and science equipment to sustain space station operations after the shuttles are retired.Only four astronauts take to the skies because there is no shuttle available for a rescue flight should anything go wrong. Normally NASA sends six or seven astronauts on space shuttle flights -- with the last four-person shuttle crew launched 28 years ago.But Atlantis' status as the final flight means there is no other space shuttle on standby and the U.S. would have to call on Russia for any rescue operation. The Russian Soyuz capsules hold just three astronauts and at least one must be Russian, so two crew members would have to fly up and bring home the Americans from the International Space Station one at a time.The crew will also return an ammonia pump that recently failed on the station. Engineers want to understand why the pump failed and improve designs for future spacecraft. One spacewalk is planned during Atlantis' mission, though it will be conducted by NASA's two resident space station astronauts, rather than the shuttle crew.It is the 33rd voyage for Atlantis. Its return to the earth later this month will mark the end of the 30-year shuttle program.Atlantis will be the last shuttle to be retired. Discovery was first in March, followed by Endeavour at the beginning of June. Each shuttle will head to a museum.When the U.S. space shuttle program officially ends later this year, the Russian space program's Soyuz capsule will be the only method for transporting astronauts to and from the station.Space shuttles have made great contributions to U.S. space exploration. They allowed astronauts to not only launch satellites, but to grab and repair them and put them back into service. Most remarkably, they allowed NASA to regularly rejuvenate the Hubble Space Telescope, which for 21 years has produced images that are transforming astronomers' understanding of the universe. With their enormous cargo bays, the shuttles also enabled the United States and its partners to build the International Space Station.However, high costs, risks, policy shift force the U.S. to quit the space shuttle program.NASA originally estimated the program would cost about 90 billion U.S. dollars. However, its actual cost stands at about 200 billion dollars, compared with the 151 billion dollars spent on Apollo which took Americans to the moon in 1969.Seven astronauts perished when Challenger exploded about a minute after launch in 1986. Nearly two decades after the Challenger explosion, a new catastrophe shocked NASA when the shuttle Columbia disintegrated moments before landing in 2003.One out of every 67 flights ended in death. Based on deaths per million miles traveled, the space shuttle is 138 times riskier than a passenger jet.The panel that investigated the 2003 Columbia accident concluded: "It is in the nation's interest to replace the Shuttle as soon as possible.''The Obama administration wants to spur private companies to get into the space taxi business, freeing NASA to focus on deep space exploration and new technology development.During his first-ever Twitter town hall meeting on Wednesday, Obama said NASA needs new technology breakthroughs to revitalize its mission to explore the universe."The shuttle did some extraordinary work in low-orbit experiments, the International Space Station, moving cargo. It was an extraordinary accomplishment. And we're very proud of the work that it did," Obama said. "But now what we need is that next technological breakthrough."
UNITED NATIONS, June 9 (Xinhua) -- The message delivered by scores of speakers on the second day of the three-day UN High Level Meeting on AIDS on Thursday, marking 30 years of the pandemic, was that most of their countries were making progress but increased efforts had to be made with greater cooperation needed among nations.In the case of developing states, gratitude was expressed for past help but more aid was needed to continue the battle.Despite the similarities in content, the chair, UN General Assembly President Joseph Deiss, repeatedly appealed to speakers to limit their speeches to their allotted five minutes, warning at the halfway point that if everyone was taking an extra few minutes, a fourth day would have to be added to the agenda.One of the briefest addresses, well under time, was delivered by Yin Li, China's vice health minister, which he referred to as " a responsible developing country."Briefly listing some of the steps taken, the Chinese vice minister focused on achieving the UNAIDS goal of the three Zs -- " Zero new HIV infections, zero discrimination and zero AIDS-related deaths.""We should unite to generate a joint force, irrespective of gender, skin color, nationality, beliefs, values and ideology. Developed countries should further provide developing countries with unselfish, unconditional financial and technical support," he said. "Developing countries should place AIDS control in a position as important as economic development and actively explore prevention and treatment mode consistent with national conditions. ""Second, given the increasing disease burden of AIDS," he said, "the private sector and relevant organizations should shoulder more social responsibility."On the one hand efforts should be made to mobilize more resources in AIDS to better implement prevention, treatment and care measures; on the other hand, multinational drug manufacturers should reduce by a large margin the price of drugs, testing equipment and reagents through technology transfer, contract manufacturing and reduction of monopoly profits in order to promote universal access to treatment services," Yin added.Since AIDS prevention and treatment in China is an important component in the global fight against AIDS, he said, "Progress made in China is a positive contribution globally."The High Level Meeting on AIDS is taking place 10 years after the UN Special Session on HIV/AIDS and five years since signing of the Political Declaration in which UN Member States committed to universal access to HIV prevention, treatment, care and support.Norway's minister of the environment and international development, Erik Solheim, said, "Prevention and treatment must be mutually reinforcing and better treatment regiments need to be made available."He called for development of innovative methods for prevention.While Solheim said "remarkable" results had been achieved in the last three decades, there still was a need for a " transformation of current working methods."AIDS must be taken out of isolation into an "integrated approach," noting that HIV response has to be connected with UN Secretary-General Ban Ki-moon's Global Strategy for Women's and Children's Health and "HIV and AIDS programs should be mainstreamed into national health systems, he said.Solheim said that the social, political and economic empowerment of women is crucial and he welcomed the establishment of the new UN agency UN Women."The burden of HIV in the world is reduced but major challenges remain," the minister said. "Our experience is that the approaches that work well on HIV, are those based on rights and on promoting the dignity of people."Celsius Waterberg, the health minister of Suriname, said the nation "is among the few countries in the Caribbean where the incidence of HIV infection has decreased by more than 25 percent."The strides forward are due to a national multi-sectoral HIV Council, setting up structures to provide leadership in quality of services and training in revised treatment protocols, he said.Suriname, the smallest sovereign state in South America, on the northeast coast of the continent, also introduced combined prevention tools and implemented pilot projects successful in mobilizing men for circumcision as an additional preventive measure, Waterberg said.Challenges that need to be overcome include harmful traditions and customs, misconceptions and adverse beliefs, language barriers in a multilingual society and vulnerability of small communities and individuals due to HIV-related stigma, gender inequalities and poverty, he said.Victor Makwenge Kaput, health minister of the Democratic Republic of Congo, said that although the government had made progress in supporting individuals living with HIV and protecting the uninfected, it continues to face many challenges. Indeed, HIV prevalence stood at 3.7 percent for pregnant women and 3 percent for the general population, he said.AIDS' victims increasingly are women and youth with infections particularly concentrated along the Congo River, the minister said. Today, 1.2 million citizens are infected. Total population in the third largest country in Africa, about the size of Western Europe, is 71 million.He said women account for roughly 71,000 new infections each year and the government is now paying particular attention to mother-to-child transmission.Kaput said his long war-torn nation is committed to the global vision of zero infections and appealed for support to curb the spread of HIV.
WASHINGTON, June 6 (Xinhua) -- The tropics and much of the Northern Hemisphere are likely to experience an irreversible rise in summer temperatures within the next 20 to 60 years if atmospheric greenhouse gas concentrations continue to increase, according to a new climate study by Stanford University scientists. The results will be published later this month in the journal Climatic Change.In the study, the Stanford team concluded that many tropical regions in Africa, Asia and South America could see "the permanent emergence of unprecedented summer heat" in the next two decades. Middle latitudes of Europe, China and North America -- including the United States -- are likely to undergo extreme summer temperature shifts within 60 years, the researchers found."According to our projections, large areas of the globe are likely to warm up so quickly that, by the middle of this century, even the coolest summers will be hotter than the hottest summers of the past 50 years," said the study's lead author, Noah Diffenbaugh, an assistant professor of environmental Earth system science and fellow at the Woods Institute for the Environment at Stanford. The study is co-authored by Stanford research assistant Martin Scherer."When scientists talk about global warming causing more heat waves, people often ask if that means that the hottest temperatures will become 'the new normal,'" Diffenbaugh said. " That got us thinking -- at what point can we expect the coolest seasonal temperatures to always be hotter than the historically highest temperatures for that season?"To determine the seasonal impact of global warming in coming decades, Diffenbaugh and Scherer analyzed more than 50 climate model experiments -- including computer simulations of the 21st century when global greenhouse gas concentrations are expected to increase, and simulations of the 20th century that accurately " predicted" the Earth's climate during the last 50 years. The analysis revealed that many parts of the planet could experience a permanent spike in seasonal temperatures within 60 years."We also analyzed historical data from weather stations around the world to see if the projected emergence of unprecedented heat had already begun," Diffenbaugh said. "It turns out that when we look back in time using temperature records, we find that this extreme heat emergence is occurring now, and that climate models represent the historical patterns remarkably well."According to both the climate model analysis and the historical weather data, the tropics are heating up the fastest. "We find that the most immediate increase in extreme seasonal heat occurs in the tropics, with up to 70 percent of seasons in the early 21st century (2010-2039) exceeding the late-20th century maximum," the authors wrote.Tropical regions may see the most dramatic changes first, but wide swaths of North America, China and Mediterranean Europe are also likely to enter into a new heat regime by 2070, according to the study.This dramatic shift in seasonal temperatures could have severe consequences for human health, agricultural production and ecosystem productivity, Diffenbaugh said. As an example, he pointed to record heat waves in Europe in 2003 that killed 40,000 people. He also cited studies showing that projected increases in summer temperatures in the Midwestern United States could reduce the harvest of staples, such as corn and soybeans, by more than 30 percent.