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SAN DIEGO (CNS) - A COVID-19 vaccine trial sponsored by drugmaker Johnson & Johnson is slated to get underway soon in San Diego, and will include an estimated 2,000 participants at UC San Diego Health, it was announced Thursday.Up to 60,000 participants will be recruited from 10 different countries around the world as the San Diego portion of the trial, dubbed ENSEMBLE, gets underway Oct. 7, according to UCSD.The efficacy, safety and immunogenicity of the drug Ad.26-COV2.S will be tested via a randomized, double-blind, placebo-controlled study, in which half of the participants receive a single-dose injection of the vaccine and the other half receive a placebo. All participants -- who must be 18 years of age or older and in reasonably good health -- will be monitored for signs of infection and COVID-19 over the next two years, according to UCSD.Researchers are particularly interested in recruiting participants at increased risk of SARS-CoV-2 infection due to where they live, their age or personal circumstances, such as working in essential jobs like first responders, health care, maintenance, construction, grocery stores or assisted living facilities.The San Diego trial will also emphasize participation from the region's underserved communities, as communities of color have shown higher rates of COVID-19-related hospitalization and/or death.UCSD cited data from the county showing measurably higher infection rates in the South Bay, including in Chula Vista, Imperial Beach and National City.Susan Little, professor of medicine at UC San Diego School of Medicine and principal investigator of the UC San Diego trial, said, "Many communities of color are experiencing higher rates of hospitalization related to COVID-19 than are observed in white, non-Hispanic people. It is important that these communities are represented in COVID-19 vaccine clinical trials so that we understand if the vaccine will work well within these groups."For more information about participating in the trial at UC San Diego, go to www.covidvaccinesd.com or call 619-742-0433. 2087

SAN DIEGO (AP) — Manny Machado went hitless in his first game with the San Diego Padres and Fernando Tatis Jr. singled twice in his big league debut, a 2-0 opening win over the San Francisco Giants on Thursday.Wil Myers homered off Madison Bumgarner in the start of a new era for the Padres, who popped above .500 for the first time since June 8, 2015.The Padres signaled their intentions to move beyond the rebuilding stage when they signed Machado to a 0 million, 10-year contract early in spring training. They then promoted Tatis Jr., whose father played in the big leagues for parts of 11 seasons, giving fans some hope after years of futility. San Diego hasn't had a winning season since 2010.RELATED: Heading to San Diego Padres Opening Day 2019? Here's what to knowMachado got a standing ovation as he walked to the batter's box for the first time with the Padres. The crowd booed when he took strike one, and the All-Star slugger struck out on three pitches. He struck out on a foul tip his next time up and then grounded into a double play.Tatis Jr. singled to left in his first big league at-bat, bouncing a ball over the glove of diving third baseman Evan Longoria in the second inning. The 20-year-old bunted for a hit his next time up, but was thrown out trying to steal second. Tatis's parents and siblings traveled from the Dominican Republic for the opener.Tatis became the youngest player with a multihit game on opening day since Milwaukee's Robin Yount in 1975.RELATED: Manny Machado signing a home run for Padres ticket, merch sales, StubHub saysMyers, batting in the No. 2 spot, just ahead of Machado, hit a 456-foot drive to right-center off Bumgarner (0-1) with two outs in the third. Myers added an RBI single in the sixth.Left-hander Eric Lauer (1-0), a 23-year-old who was on an opening-day roster for the first time, threw six innings of four-hit ball. Bumgarner (0-1) struck out nine while allowing two runs and five hits in seven innings.RELATED: Brews outside Petco: Breweries to visit before, after the ballgame downtownIt was the beginning of the end for Giants manager Bruce Bochy, who announced in spring training that he will retire at the end of this season, his 25th as a big league manager. He managed the Padres from 1995 until being pushed out after a playoffs loss to St. Louis in 2006. While San Diego hasn't been back to the postseason since, Bochy was snapped up by the Giants and managed them to three World Series titles in five seasons starting in 2010.Kirby Yates pitched the ninth for the save.YOUNG ONEAt 20 years, 85 days, Fernando Tatis Jr. is the youngest Padres player to play on opening day and the youngest to play in a game since Roberto Alomar in 1988. He is the fifth-youngest Padres player ever.UP NEXTGiants: LHP Derek Holland, who was 7-9 with a 3.57 ERA last year, gets the start Friday night.Padres: LHP Joey Lucchesi, 8-9 with a 4.08 ERA as a rookie last year, is scheduled to start the second game of the four-game series. 3000

SAN DIEGO (CNS) - A 59-year-old woman suffered a fractured back when she was struck by a hit-and-run motorist in the Clairemont Mesa West community of San Diego, a police officer said Sunday.The woman was crossing westbound in the south crosswalk when she was hit a little before 6:25 p.m. Saturday by a vehicle that had been going westbound on Derrick Drive and made a left turn to southbound Genesee Avenue, said Officer Robert Heims of the San Diego Police Department.Police had no description of the vehicle or the motorist. Paramedics rushed the woman to an area hospital with a fractured back, Heims said.Anyone who saw the crash was asked to call Crime Stoppers at (888) 580- 8477. 696

SAN DIEGO — Home construction in the city of San Diego increased in 2019, but is still far off pace to meet the region's high demand for housing.The findings come in a report released Tuesday by the city's planning department.It shows that in 2019 the city issued 5,221 permits for new housing units, up from 3,895 the year before. Still, that's way off pace for any sort of building activity that could help lower the cost of housing. Consider that the city only issued permits for 42,275 housing permits from 2010 to 2019, which is 48 percent of its goal of 88,096. The city says it issued permits for 940 affordable housing units in 2019 and 456 granny flats in 2019."This year's report shows early success for our recent initiatives," City Planning Director Mike Hansen said in a statement. "However, it's important the City continues to adopt new housing reforms to meet new, ambitious housing targets and address all of San Diego's housing needs."For 2020 to 2029, the city has a goal of 108,000 new homes. The city has created incentives such as waiving parking requirements in transit priority areas, offering density bonuses to developers who include affordable housing, and waiving water and sewer fees for accessory dwelling units (aka granny flats). Still, the median price for a single family home in the 6,000 in June, according to Corelogic. Meanwhile, the average rent was ,237 per month, according to RentCafe. 1441

SAN DIEGO (CNS) - A former La Jolla Country Day School teacher who had a sexual relationship with a 17-year-old female student over the course of several months was sentenced Wednesday to probation and community service and was prohibited from teaching again in any capacity.Jonathan Sammartino, the 37-year-old son of U.S. District Judge Janis Sammartino, could have faced up to one year in local custody and sex offender registration following his guilty plea to a felony count of unlawful sexual intercourse with a minor. He previously faced two other felony sex counts that could have had him facing prison time, but those counts were dismissed after he pleaded guilty in August.Deputy District Attorney Martin Doyle said the plea agreement was reached in part because the victim, identified only as "Jane Doe" in court proceedings, did not want the case to go to trial. She also declined to virtually attend Wednesday morning's sentencing hearing.Doyle said the victim was content that the case is resolved and has "changed and healed" since her interactions with Sammartino, which occurred in 2016."It's her wish to move on with her life," the prosecutor said.San Diego County Superior Court Judge Charles G. Rogers ordered the defendant to complete his 400 hours of community service at any nonprofit organization by next August.In declining to impose sex offender registration, Rogers cited a U.S. Supreme Court case that found registration was most suited for those considered dangerous and likely to re-offend.The judge said though Sammartino's conduct toward the victim could be considered predatory, due to their age difference and his abuse of a position of trust, "there is not an iota of evidence that this conduct was an expression of an underlying character trait on his part. I see no indication that this man is predatory or is likely to repeat this conduct with another person or is a danger to others."Rogers also cited a bicycling accident Sammartino suffered about a year prior to the offenses, which the defendant and his attorney say caused a brain injury that inhibited his impulse control and ability to make reasonable judgments. The judge said he didn't think the injury excused Sammartino, but said he believed it was a contributing factor to the offenses.Sammartino made a statement to the court, in which he said, "I am very sorry for everything that has happened and for the misery caused by my unfortunate involvement with Ms. Doe. I know that my behavior's disrupted her life, my own life, and the community."He said he was "not the same person" he was before the bicycling accident and was continuing to seek treatment for "my mental impairments that led to those behaviors."Sammartino said he would find another line of work in order to serve the community.Though his probation terms prohibit him from teaching, his attorney, Eugene Iredale, said Sammartino's doctoral degree precluded him from needing a teaching credential, which he would otherwise be required to surrender.Instead, Iredale said his client has pledged not to teach again, and cannot do so in any practical way, "because in the age of the internet, there is truly no ancient history.""As, of course, a condition of this plea agreement, and without hesitation, he has pledged that he will not seek to teach anywhere ... and that means anywhere at any level in any way, including private tutoring, including college instruction or community college," the defense attorney said.In testimony earlier this year at Sammartino's preliminary hearing, the victim said the first sexual encounter happened in early 2016, when he arrived at her home unannounced around midnight. She said she went outside to meet with him in his car, at which point he told her he didn't trust himself around her.Sexual encounters occurred that night in his car and on several other occasions in his vehicle and his house over the next few months, she testified.The victim, who went on to attend UC Berkeley, filed a report with campus police in the summer of 2018. Charges were filed later that year.In a recorded phone call played during the preliminary hearing, Sammartino admitted to the past encounters with the victim."Why did you do it? You knew I was 17," Doe says on the recording. "You knew I was your student. You knew it was my first time and I lost my virginity to you.""I don't have a good answer, because I wasn't thinking through what I was doing," he replied, apologizing to her several times throughout the call. "I can't believe that I did that." 4549

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