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BEIJING, May 10 (Xinhuanet) -- Researchers from California, Unated States, found that sexual orientation could play a role in cancer and more gay men are reported being cancer survivors than straight men, according to findings in the journal Cancer online Monday.The researchers found that gay men are 1.9 times more likely than straight men to report having had cancer. They also found that lesbian and bisexual women are more than twice as likely as heterosexual women to report fair or poor health after having cancer.Researchers looked at three years of responses to the California Health Interview survey, which included more than 120,000 adults living in the state.Among other health-related questions, participants were asked if they had ever been diagnosed with cancer and whether they identified as gay, lesbian, bisexual, or straight.Out of 51,000 men, about 3,700 said they had been diagnosed with cancer as an adult. While over 8 percent of gay men reported a history of cancer, that figure was only 5 percent in straight men, a disparity that could not be attributed to differences in race, age or income.About 7,300 out of 71,000 women in the study had been diagnosed with cancer, but overall cancer rates did not differ among lesbian, bisexual, and straight women.Ulrike Boehmer, the study's lead author from the Boston University School of Public Health, said higher rates of human immunodeficiency virus (HIV) may be related to the increased risk of cancer in gay men.However, the findings do not necessarily mean that being gay, lesbian or bisexual increases risk of cancer, said the researcher.
WASHINGTON, April 6 (Xinhua) -- A study led by researchers at the University of Michigan (U-M) showed in animal studies that new cancer drug compounds they developed shrank tumors, with few side effects.The study, done in two mouse models of human cancer, looked at two compounds designed to activate a protein that kills cancer cells. The protein, p53, is inactivated in a significant number of human cancers. In some cases, it is because another protein, MDM2, binds to p53 and blocks its tumor suppresser function. This allows the tumor to grow unchecked. The new compounds block MDM2 from binding to p53, consequently activating p53."For the first time, we showed that activation of p53 by our highly potent and optimized MDM2 inhibitors can achieve complete tumor regression in a mouse model of human cancer," says lead study author Shaomeng Wang, director of the Cancer Drug Discovery Program at the U-M Comprehensive Cancer Center.Wang presented the study Wednesday at the American Association for Cancer Research 102nd annual meeting.Many traditional cancer drugs also activate p53 but they do so by causing DNA damage in both tumor cells and normal cells, causing side effects. These new MDM2 inhibitors activate p53 while avoiding the DNA damage common with other drugs. In this study, which was done in collaboration with Ascenta Therapeutics and Sanonfi-Aventis, researchers showed that these new drugs shrank tumors without significant side effects.Because p53 is involved in all types of human cancer, the new drug has potential to be used in multiple types of cancer. Further, the researchers also identified certain markers in tumors that predict which ones will be particularly sensitive to the MDM2 inhibitor, which would allow physicians to target the drug only to patients most likely to benefit.
BEIJING, May 16 (Xinhuanet) -- NASA is close to deciding on a landing site for its Mars rover Curiosity mission by narrowing the choices to four, media reports said Monday.Scientists in the close-knit Mars research community get one last chance to make their case this week when they gather before the "judges" — the team running the 2.5 billion U.S. dollar mission that will soon suggest a landing site to NASA, the ultimate decider."All four of these places are compelling places on Mars to study. There's not a loser among them," said landing site scientist Matt Golombek of the NASA Jet Propulsion Laboratory, one of the meeting's leaders.The mission will use rover Curiosity to study whether a selected area will have environmental conditions suitable for life and for preserving evidence about whether extraterrestial life has existed.Being nuclear-powered, the rover cannot go to a location that has either water or ice within one meter of the surface.The size of a mini Cooper, Curiosity is scheduled to launch in late November after a two-year delay.
BEIJING, Feb. 27 (Xinhua) -- Chinese Premier Wen Jiabao said during an online chat with netizens here Sunday that the government is striving to ensure that the people live a comfortable life with security and confidence in the period of 2011-2015.China's development blueprint for the coming five years will place high emphasis on the efforts to improve the people's livelihood, Wen said.To enhance the people's living standards is "our work's starting point as well as the final aim," he said.Greater efforts will be made to boost social development and progress, especially in those key sectors and aspects concerning national development and mass interests, the premier said.Wen began his online chat with netizens at 9 a.m. Sunday jointly hosted by the central government website (www.gov.cn) and Xinhua News Agency website (www.news.cn).
BEIJING, May 25 (Xinhua) -- A researcher with the Chinese Academy of Agricultural Sciences (CAAS) said Wednesday that plant hormones, if used properly, are not a risk to human health."Irregular use of plant growth substances may cause plants to grow excessively fast or affect the taste, but will not cause harm to human health," Ye Zhihua said in an interview with Xinhua.His remarks come after media reports in China about "exploding watermelons," caused by the excessive use of phytohormone, have aroused public concern over the safety of hormones that stimulate plant growth.Ye said plant hormones used to promote growth have the same or similar effects as natural plant hormones, and fruit and vegetables sold at the market carried limited residue of the hormones.More than 100 types of plant hormones, such as ethephon and gibberellin acid, are used in agriculture and forestry sectors around the world, Ye said, adding 38 types of plant hormones have been registered in China.For example, seven plant hormones including thidiazuron and nucleotide are approved for use on cucumbers in China. The purpose is to stimulate the growth of female flowers and increase fruit yields, Ye said.Ye added that China places plant hormones in the category of pesticides control, which means the hormones are subject to strict management from production to utilization.