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BEIJING, Aug. 22 (Xinhuanet) -- Researchers have discovered how a human egg captures an incoming sperm for fertilization, paving the way to help couples suffering from infertility, according to media reports on Monday.An international team of researchers found that a sugar chain known as the sialyl-lewis-x sequence (SLeX) makes the outer coat of the egg “sticky,” which has proven to be helpful in binding the egg and the sperm.As a result, this observation has filled in a huge gap in the understanding of fertility and provides hope for ultimately helping couples who currently cannot conceive.Scientists and doctors know that a sperm identifies an egg when proteins on the head of the sperm match and bind to a series of specific sugars in the egg’s outer coating. With a successful match of proteins, the outside surfaces of the sperm and egg then bind together before merging, which is then followed by delivery of sperm’s DNA into egg.To identify this molecules, the researchers used ultra-sensitive mass-spectrometric imaging technology to observe and identify which molecules are most likely to be key in the binding process.They experimented with a range of synthesised sugars in the laboratory and found that it is SLeX that specifically binds sperm to an egg.According to the World Health Organisation, infertility affects about 15 percent of reproductive-aged couples around the world and almost one in every seven couples in Britain has problems conceiving a child for various reasons.

BEIJING, July 11 (Xinhuanet) -- U.S. federal government officially announced that it denied the medical use of marijuana."Department of Health and Human Services concluded that marijuana has a high potential for abuse, has no accepted medical use in the United States, and lacks an acceptable level of safety for use even under medical supervision," U.S. Department of Justice declared Friday.The announcement will keep marijuana in the classification of dangerous, addictive drug as heroin.The decision comes almost nine years after medical marijuana advocates asked the government to reclassify marijuana, as its therapeutic effectiveness in treating some diseases and relieving pain of patients.Joe Elford, the chief counsel for Americans for Safe Access (ASA), said he was not surprised by the government's disapproval."It is clearly motivated by a political decision that is anti-marijuana," He noted.This is the third petition to reclassify marijuana has failed to be approved. The former two were filed in 1972 and in 1995, respectively.

UNITED NATIONS, Sept. 19 (Xinhua) -- Mohammad Hossein Niknam, acting minister of health in international affairs of Iran, said here on Monday that his country is working to prevent and counteract the non-communicable diseases (NCDs), which have had significant effect on the population."NCDs have traditionally been more prevalent in affluent societies," he said. "However, they are increasingly becoming common in many developing countries, and in particular among the less affluent groups. The Eastern Mediterranean Region (EMRO) as others is suffering a heavy burden of NCD diseases and Iran is no exception: the total burden of disease for NCDs is 45 percent for males and 33 percent for females."Niknam's statements came as he addressed the UN General Assembly High-Level Meeting on Prevention and Control of Non- communicable Diseases."This timely high-level event provides us with an ideal platform to share views, information, ideas and experiences, to come up with remedial proposals and to forge effective collaborative partnerships in the implementation of realistic but effective health development programs in common areas of concern pertaining to the non-communicable diseases," Niknam said.He explained that Iran is implementing a series of programs in order to reduce the frequency and impacts of NCDs."As part of these programs I would like to mention prevention and control of common NCDs risk factors, imposition of taxes to curtail unhealthy habits such as tobacco consumption, execution of mass public information and educational campaigns, fostering food industry regulations, screening of blood pressure levels and high glucosemia," he said.Iran has created a Non-Communicable Diseases Risk Factor Surveillance System, according to Niknam. This system, in place since 2004, has conducted six large-scale surveys to gather information helpful to public health."Further, comprehensive cumulative national data has been compiled based on age, sex and location to facilitate effective monitoring and implementation of policies geared towards control and prevention of NCDs," Niknam said.Iran is conducting many other integrated NCD control and prevention programs, such as, to name a few, a Cardiovascular Diseases Control Program for rural areas; a National Cancer Control Program focusing on breast and colorectal cancers; and a Diabetes Control and Prevention Program that targets both rural and urban areas.Niknam ended his statement by noting that Iran has held regional consultations on the NCD issue."I would like to conclude my remarks by mentioning that as a sign of its commitment to promote regional and international cooperation, the Islamic Republic of Iran hosted on 25-26 October 2010 in Tehran the first regional meeting of a series of the regional consultations held by WHO (World Health Organization) on the prevention and control of NCDs," he said. "In our understanding, only through closer and meaningful collaboration at all levels, especially in areas such as legislation, resource mobilization and information and knowledge sharing, we may success in our endeavor to prevent and combat NCDs."

BEIJING, July 25 (Xinhuanet) -- Apple is planning a third, even larger Shanghai store, as well as dozens of other stores throughout China, to cope with huge crowds at its flagship store and a branch, according to media reports Monday.Apple says its Chinese outlets -- two in Beijing and two in Shanghai -- are the four most heavily trafficked Apple stores in the world. They also generate the most revenue. Apple’s push into China shows the depth of the country’s fast-growing economy, and shows that with products not so easy to counterfeit, Chinese consumers are willing to pay a premium.For the first three quarters of Apple’s fiscal year, revenue in China and its Taiwan, Hong Kong was 8.8 billion dollars -- six times that of a year earlier. China has become the second-largest market, after the United States, for apps that run on the smartphone and tablet, according to Distimo, a Dutch company that tracks the popularity of apps.In addition, Apple has been eager to team up with state-run telecom companies, which looks after mobile phone subscriptions.

WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.