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The U.S. will pay drug company Pfizer .95 billion to produce and deliver 100 million doses of the company's COVID-19 vaccine candidate should the drug prove effective in human trials the company said in a press release on Wednesday.Pfizer will deliver the vaccine if and when the drug receives Emergency Use Authorization from the FDA after a large-scale Phase 3 trial.According to the reports, the deal includes an option for the government to purchase an additional 500 million doses of the vaccine.“Expanding Operation Warp Speed’s diverse portfolio by adding a vaccine from Pfizer and BioNTech increases the odds that we will have a safe, effective vaccine as soon as the end of this year,” Health and Human Services Sec. Alex Azar said in a statement. “Depending on success in clinical trials, today’s agreement will enable the delivery of approximately 100 million doses of this vaccine to the American people.”Pfizer and German firm BioNTech are working together to develop the vaccine.On Monday, Pfizer said in a press release that results from Phases 1 and 2 of a German trial indicated that the drug "could potentially be administered safely, with a manageable tolerability profile," according to data from the tests.Biotech company Moderna is also working to develop a coronavirus vaccine. That candidate will move into Phase 3 testing by the end of the month, and the government has also agreed to purchase and distribute the drug should the large-scale test prove effective. 1497

The Sikh community is speaking out after a Sikh Canadian minister was asked to take off his turban while going through a TSA checkpoint at Detroit Metro Airport.The incident happened in April 2017.  Navdeep Bains, Canada’s Minister of Innovation, Science and Economic Development, went through the TSA checkpoint once without any issues but was asked to go through additional screenings because of his turban."Once they realized my position, who I was, I was ultimately allowed to fly but for me this is an issue that speaks for discrimination and discrimination happens with many people," Bains said. The agency is now issuing a statement and the U.S. government is apologizing to Canada.TSA responded to the incident saying in part: 767

The storm-weary Carolinas are preparing for another round of strong winds and drenching rains -- this time from Hurricane Michael.Michael is speeding toward the Florida Panhandle as a Category 4 storm, and is expected to make landfall Wednesday afternoon.From there, it'll move into the Southeast and some areas in North and South Carolina, where it's expected to bring strong wind gusts and drop 3 to 5 inches of rain when it passes central parts of the states Thursday and Friday, CNN meteorologist Michael Guy said.While it doesn't sound like much compared to last month's record Florence rainfall of 30 inches or more in some areas, any amount of rainfall on already saturated grounds could lead to flooding.Northeast South Carolina, from Columbia toward Myrtle Beach, and southeast North Carolina, were among the areas hardest hit by Florence, and will get a drenching from the latest hurricane, Guy said. While the rain will move quickly compared to Florence, it'll still bring flooding possibilities. 1015

The Sinaloa drug cartel, once run by one of the most wanted men in the world, El Chapo, has made its way to Northeast Ohio. It's a drug-trafficking ring moving large amounts of drugs from Mexico onto the streets."I don't think people understand how significant and embedded it is in Northeast Ohio," said Keith Martin, Assistant Special Agent in Charge of Cleveland's Drug Enforcement Administration. Authorities recently found a stash house in a Maple Heights neighborhood and another on Cleveland's west side. "The unfortunate fact is the drugs on our streets come from somewhere. Coco plants don't grow in Cleveland. Poppy plants don't grow in Parma, they come from somewhere else. They are, increasingly, in almost every case, the drugs are coming from Mexican cartels," said Justin Herdman, U.S. Attorney for the Northern District of Ohio. A three-year long DEA investigation, dubbed "Operation Loaded Deck," focused on taking down the local arm of the notorious Sinaloa cartel. During the investigation, authorities seized large quantities of heroin, cocaine and fentanyl, some of which were concealed in hidden compartments in cars. The drugs were moved across the U.S.-Mexican border and transported in these cars outfitted with secret traps. "Often times they'll go to great lengths, whether they've constructed a trap in a vehicle or a natural void in the vehicle," Major Gene Smith with the Ohio State Highway Patrol said.Just as astonishing, Cartel members were hiding in plain sight the whole time, even taking in a Cavaliers game — courtside."These aren't street-level dealers, they were dealing in massive quantities and, in return, huge amounts of cash," Herdman said. By the end of the investigation, 29 kilos of cocaine, eight kilos of heroin, a kilo of fentanyl and four pounds of marijuana were seized, along with nearly 0,000, guns, vehicles and dozens of cell phones. Operation Loaded Deck ended with 19 people sent to federal prison for their roles in the drug trafficking organization. 2115

The Special Counsel's Office is hoping to deny an attempt by several media organizations, including CNN, to unseal documents in the Russia probe, by arguing that the documents need to remain private because of the breadth of still-secret parts of the ongoing investigation."The Special Counsel's investigation is not a closed matter, but an ongoing criminal investigation with multiple lines of non-public inquiry. No right of public access exists to search warrant materials in an ongoing investigation," Robert Mueller's team wrote in a filing Wednesday night.The prosecutors wrote in the firmest language yet about how their yearlong investigation into Russian interference in the 2016 US election continues and includes several interconnected parts, some of which may link back to searches of the belongings of former Trump campaign chairman Paul Manafort that were also used to build cases against him unrelated to his work for the campaign.Manafort faces criminal indictments in Virginia and DC federal courts related to his foreign lobbying business from before the campaign. He's pleaded not guilty in both.Prosecutors have previously revealed that the Justice Department directed Mueller to look into allegations that Manafort coordinated with Russians during the campaign, yet they have not previously hinted that others besides Manafort could be central to the Russia probe. Wednesday's court filing acknowledges multiple relationships that are part of investigative threads."The investigation consists of multiple lines of inquiry within the overall scope of the Special Counsel's authority. Many aspects of the investigation are factually and legally interconnected: they involve overlapping courses of conduct, relationships, and events, and they rely on similar sources, methods, and techniques. The investigation is not complete and its details remain non-public," prosecutors wrote.If they were to be unsealed, "warrant materials reveal investigative sources and methods, preliminary factual and legal theories, and evidence that has already been gathered -- including from grand jury processes. They show what has been searched -- including electronic facilities where the search itself is protected by a non-disclosure order -- and indicate what has not been searched. And the dates and volume of warrants reveal an investigation's direction."The Special Counsel's Office said it wouldn't oppose formally unsealing two search warrants that were made public through recent court filings in Manafort's case, though parts of them remain heavily redacted.CNN, along with The Associated Press, Politico, The Washington Post and The New York Times, initially asked the court to unseal all the search warrants used in the investigations and other sealed documents related to Manafort's two federal criminal cases. 2838