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The family of Stephon Clark, the 22-year-old black man shot and killed by Sacramento Police, will be exploring "every legal remedy possible" in search of justice, according to their attorney Benjamin Crump.Speaking to CNN on Sunday, Crump said Clark's death should not be "swept under the rug." Crump also called for accountability from both sides."There's great mistrust" between communities of color and police, Crump told CNN's Dan Simon. The attorney has also represented the families of Trayvon Martin, Michael Brown and Tamir Rice. 545

The funeral for Aretha Franklin will be held August 31 in Detroit, according to the singer's publicist, Gwendolyn Quinn.The service, for family and friends, will be held at 10 a.m. ET that day at Greater Grace Temple.Public viewings will be held August 28 and 29 from 9 a.m. to 9 p.m. at the Charles H. Wright Museum of African American History in Detroit, Quinn said.Franklin will be entombed at Woodlawn Cemetery in Detroit.The legendary soul singer died Thursday from advanced pancreatic cancer. She was 76. 518

The Food and Drug Administration says it is re-examining the safety of a medication that was approved despite concerns that not enough was known about the drug's risks.In response to questioning at a budget hearing last week, FDA Commissioner Scott Gottlieb told members of Congress that he would "take another look" at Nuplazid, which is the only drug approved to treat hallucinations and delusions associated with Parkinson's disease psychosis.The medication has been cited as a so-called "suspect" medication in hundreds of deaths voluntarily reported by caregivers, doctors and other medical professionals since it hit the market, as highlighted in a recent CNN report.The FDA told CNN this week that the agency had already begun conducting a new evaluation of the medication when Gottlieb was questioned about it at the hearing. The agency said the review had started several weeks ago."What does it take for a drug like this to be taken off the market?" asked US Rep. Rosa DeLauro, a member and former chair of the congressional subcommittee responsible for funding and overseeing the FDA.DeLauro pressed Gottlieb for answers on his agency's response to the safety concerns surrounding Nuplazid."How many more adverse events do we have to have reported? How many people, quite frankly, have to die? Why does the industry always take precedence over public health and safety?"Tracked by the FDA, the adverse event reports cited by DeLauro do not mean that a suspected medication has been ruled the cause of harm and are typically not the result of official investigations. But the FDA uses the information to monitor potential issues with a drug and can take action as needed: updating a medication's label, for instance, or restricting its use. In rare cases, the agency can even pull a drug off the market.When asked by CNN about what prompted the FDA's new evaluation of Nuplazid, the agency said the decision was based on a number of factors but wouldn't say what those factors were. Instead, it would only comment generally, saying that it identifies "potential signals of serious risk/new safety information" in part by using adverse event data and that the agency is not suggesting physicians stop prescribing the drug or take patients off of it while a safety evaluation is taking place.The FDA has noted that the death reports citing Nuplazid have typically involved elderly patients with advanced-stage Parkinson's disease who suffered from numerous medical conditions and often take other medications that can increase the risk of death.But physicians, researchers and other medical experts told CNN that the high number of reports deserved a closer look to determine whether they were related to the drug. They also recommended further testing of Nuplazid, worrying that the drug had been approved too quickly, based on too little evidence that it was safe or effective.Nuplazid's review was expedited by the FDA because it had been designated a "breakthrough therapy," meaning it demonstrated "substantial improvement" in patients with serious or life-threatening diseases compared to treatments already on the market.Dr. Paul Andreason, the physician who led the FDA's medical review of Nuplazid, warned that patients taking the drug during the company's clinical trials experienced serious outcomes, including death, at more than double the rate of those taking the placebo. But the FDA ruled that the potential benefits outweighed the risks, agreeing with an advisory committee that cited a lack of safe alternatives and the pleas from family members who claimed the drug was already helping or could help their loved ones.At that advisory committee meeting two years ago, one woman said that her grandmother had been part of the clinical trials for the drug and that Nuplazid had been life-changing."We didn't know what to expect or even if she was on the drug" or a placebo, said Zoey Wade. "We soon realized that she must be taking the drug, because she really returned to herself. Her hallucinations reduced, and she better understood what was real and what was imaginary."Shortly after Nuplazid's release, however, patients' family members, doctors and other health care professionals started reporting "adverse events" possibly linked to the medication -- including deaths, life-threatening incidents, falls, insomnia, nausea and fatigue.During the first 10 months Nuplazid was on the market, 244 deaths were reported to the FDA in which Nuplazid was a "suspect" medication, according to an analysis conducted by the Institute for Safe Medication Practices. FDA data now show that the number of reported deaths has risen to more than 700. In more than 1,000 reports, patients continued to experience hallucinations while on Nuplazid.After CNN published its investigation on Nuplazid, reporters were contacted by family members who said the drug helped tame hallucinations with few apparent side effects and others who said they believe Nuplazid contributed to their family member's decline or death. Some said they had not yet reported these experiences to the drugmaker or the FDA.While the FDA has long been criticized for being too slow to approve drugs, DeLauro seized on its push to streamline the process, lambasting the agency for putting industry interests and efficiency above public health and safety.DeLauro described the number of adverse events and deaths as "staggering" and "unprecedented." She also expressed concern that the drugmaker, Acadia Pharmaceuticals, is attempting to get the drug approved for a larger population: patients who suffer from dementia-related psychosis."I don't know why it should stay on the market, especially when the FDA has not determined it to be safe and while the number of adverse events continues to soar," she told Gottlieb.In response to the congresswoman's remarks, Acadia told CNN that adverse event data alone are "not a comprehensive and accurate indicator of the safety profile of any drug." In response to CNN's earlier report on the drug, Acadia said there are a number of reasons for the higher volume of death reports, including the fact that the company distributes Nuplazid through a network of specialty pharmacies that puts the company in more frequent contact with both patients and caregivers -- meaning Acadia is more likely to receive reports of death, which it is required to pass along to the FDA.Commissioner Gottlieb told the committee that the FDA is careful about the decisions it makes and that there may be a higher tolerance for risk in situations where there is an unmet medical need, "so long as the patient is properly informed of what those risks are." This echoed what he told CNN's Dr. Sanjay Gupta in an interview earlier this month.The FDA previously told CNN that it was aware of Nuplazid's "complex safety profile" at the time of approval and required the drugmaker to place warnings on its labeling. The agency also said that, though it was continuing to monitor available information about Nuplazid, it had "not identified a specific safety issue" not already reflected on the medication's label.DeLauro's office told CNN that it plans to follow up with the FDA about its inquiry into Nuplazid. 7224

The CEOs for auto giants Kia and Hyundai have refused to attend a congressional hearing to explain why hundreds of their vehicles have spontaneously burst into flames.Both carmakers and a spokesman for Democrats on the Senate Committee on Commerce, Science and Transportation have confirmed the companies’ refusal to send representatives to the hearing, which has been scheduled for next week.A Kia spokesman said the company is working with the committee to “analyze all relevant information associated with any fire or other safety-related matters and will take any necessary corrective action in a timely manner.”A Hyundai spokesman said, “Hyundai takes this matter very seriously, and fully appreciates the concerns of the Senate Commerce, Science & Transportation Committee including those of the Chairman and Ranking Member.”It was not immediately clear whether the U.S. Senate committee would postpone or cancel its Nov. 14 hearing on Kia and Hyundai fires.The call for the hearing came six months after Consumer Investigator Jackie Callaway, of WFTS television station in Tampa, Florida, first reported on the unexplained car fires.Since April, the WFTS I-team has exposed hundreds of Kia and Hyundai models manufactured since 2011 that caught fire across the country.“The hearing will focus on motor vehicle safety issues involving vehicle fires,” stated the identical letters – dated Oct. 16 – and sent to Kia Motors America President and CEO Seungkyu “Sean” Yoon and Hyundai Motor America's Kyung Soo “Kenny” Lee.The CEOs were asked to “promptly identify and respond to defects that may pose a fire risk” at the Nov. 14 hearing in front of the Senate Committee on Commerce, Science and Transportation.In September, an Ohio mother spoke out and called for a federal investigation after watching her son burn alive in her 2014 Kia Soul parked at her apartment complex just outside of Cincinnati last year. 1926

The former Dean of the Michigan State University College of Osteopathic Medicine and boss of Dr. Larry Nassar is facing four different charges, including criminal sexual conduct, after his arrest on Monday night.According to a court record, William Strampel is charged with fourth degree criminal sexual conduct, two counts of willful neglect of duty and common law offenses.Fourth degree CSC includes force or coercion. It's expected Strampel will be arraigned on these charges in Ingham County on Tuesday afternoon. 530

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