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WASHINGTON, July 15 (Xinhua) -- Coastal communities along the U. S. East Coast may be at risk to higher sea levels accompanied by more destructive storm surges in future El Nino years, according to a new study published Friday by the U.S. National Oceanic and Atmospheric Administration (NOAA).The study was prompted by an unusual number of destructive storm surges along the East Coast during the 2009-2010 El Nino winter.The study, led by Bill Sweet, from NOAA's Center for Operational Oceanographic Products and Services, examined water levels and storm surge events during the "cool season" of October to April for the past five decades at four sites representative of much of the East Coast: Boston, Atlantic City, Norfolk and Charleston.From 1961 to 2010, it was found that in strong El Nino years, these coastal areas experienced nearly three times the average number of storm surge events (defined as those of one foot or greater). The research also found that waters in those areas saw a third-of-a-foot elevation in mean sea level above predicted conditions."High-water events are already a concern for coastal communities. Studies like this may better prepare local officials who plan for or respond to conditions that may impact their communities," said Sweet. "For instance, city planners may consider reinforcing the primary dunes to mitigate for erosion at their beaches and protecting vulnerable structures like city docks by October during a strong El Nino year."El Nino conditions are characterized by unusually warm ocean temperatures in the Equatorial Pacific that normally peak during the Northern Hemisphere "cool season." They occur every three to five years with stronger events generally occurring every 10-15 years. El Nino conditions have important consequences for global weather patterns, and within the U.S., often cause wetter-than- average conditions and cooler-than-normal temperatures across much of the South.

LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

BEIJING, August 23 (Xinhuanet) -- In the U.S., the rate of injuries related to children and teens falling out of windows declined over a 19-year period, although not nearly as fast as in some cities with comprehensive prevention programs, researchers found.From 1990 to 2008, the overall rate of injuries in children and teens was 7.3 per 100,000 per year, going as high as 11.4 in 1992 and as low as 5.8 in 1999, according to Gary Smith, MD, DrPh, of the Research Institute at Nationwide Children's Hospital in Columbus, Ohio, and colleagues.The annual rate of injuries fell slightly but significantly over the study period, driven entirely by a reduction of 0.426 cases per 100,000 per year in children up to age four, the researchers reported online ahead of the September issue of Pediatrics.That is much less than the reduction seen in previous studies of fall prevention programs in New York City and Boston, which achieved declines of up to 96 percent during a 10-year period through education, increased access to window guards, and a mandate to use window guards in certain homes (only in New York City)."The slower decrease followed by a plateau in injury rates found in this study underscores the fact that prevention efforts of the magnitude undertaken in New York and Boston have not occurred nationwide," Smith and hiscolleagues wrote.The researchers also acknowledged that the study underestimated the number of injuries related to falling out of a window because it included only those children treated in emergency rooms. An additional limitation is that the case narratives often lacked details about the circumstances surrounding the injury, including any suicidal intent.

BRUSSELS, May 31 (Xinhua) -- A deadly outbreak of E.coli linked to contaminated cucumbers is sending Europe on high alert, as death toll from the disease climbed to 16 till Tuesday.So far, 15 people have reportedly died and more than 300 were seriously ill from infections linked to tainted vegetables in Germany. Experts said the numbers are expected to increase in the coming week."We hope the number of cases will go down but we fear it will worsen," said Oliver Grieve, spokesperson with the University Medical Center Schleswig where most German victims are being treated.The German government has identified the pathogen as hemolytic-uremic syndrome (HUS), a serious complication of a type of E. coli known as Shiga toxin-producing E.coli (STEC). The bacteria could damage blood cells and kidneys, and hence cause deaths.A woman in her 50s was confirmed to be the first fatal victim out of Germany by a local hospital on Tuesday. Officials at the hospital in Boras, southwestern Sweden, said the woman, who had recently traveled to Germany, was admitted on May 29.Swedish health authorities already said on Sunday that 36 people, all linked to travel in northern Germany, had been confirmed to have infected with E.coli, whereas cases were also reported in France, the Netherlands, Denmark and Britain.It was the second food scare for European consumers this year. In January, highly toxic dioxin was found in eggs, poultry and pork products across Germany.

SAN FRANCISCO, June 14 (Xinhua) -- Apple updated its online store on Tuesday to begin offering unlocked models of iPhone 4 in the United States for the first time."The unlocked iPhone 4 requires an active micro-SIM card that you obtain from a supported GSM wireless carrier," said Apple in the product description. The iPhone requires a smaller version of the standard SIM (Subscriber Identity Module) card.Started at 649 U.S. dollars for the 16 GB version, the unlocked model is a GSM phone, which means, in the United States, the phone runs on networks of T-Mobile or AT&T, although it can only send data over T-Mobile's old EDGE network, not its 3G network and the faster HSPA+ network.Verizon and Sprint, the other two major U.S. wireless carriers, both use CDMA networks that do not use SIM cards.The iPhone 4 has been sold unlocked in other countries. For frequent international travelers, an unlocked iPhone means they just need to pop in a micro-SIM card for whichever country they are going, avoiding provider's high international fees.According to Apple, iPhone sales grew 113 percent year over year in the second quarter of its fiscal 2011, reaching a record high of 18.65 million units.

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