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CANBERRA, Sept. 9 (Xinhua) -- Australia on Friday launched the first national study to find out whether low to moderate levels of alcohol drank by pregnant women are harmful or not to an unborn child, hoping to provide a clear indication about the safe amount of alcohol for pregnant women.The Murdoch Children's Research Institute in Melbourne, which commissioned the study, is recruiting 2000 pregnant women who will be quizzed throughout their pregnancy about their drinking habits, general health and diets.Their babies will then undergo medical checks, when they turn one and again at two to see if their brains, development and behavior was affected by alcohol consumed by their mums.According to lead researcher associate professor, Jane Halliday, while there was solid evidence about the dangers of heavy drinking for an unborn baby, it was not known if there was a safe amount of alcohol pregnant women could drink.She said the study hoped to shed light on the best approach to alcohol use during pregnancy."The problem is that for about half of women that get pregnant it is unplanned, and a lot of women are drinking around the time they get pregnant and may drink for the first month or so and that creates a lot of anxiety," Assoc Prof Halliday said in a statement."From the few international and Australian studies there's conflicting evidence as to whether there's an adverse effect."We firmly believe that no drinking is the safest option, but our main aim is to provide an evidence base to the policy and answer questions about individual risks."The study came after research by the University of Newcastle published in 2010 revealed 80 percent of Australian women drank during pregnancy.
SYDNEY, Aug. 5 (Xinhua) -- The Western Australian Government announced on Friday that 14 new substances linked to the manufacture of the synthetic drug Kronic would be banned from Friday midnight.The State Mental Health Minister Helen Morton told the Australian Broadcasting Corporation (ABC) Radio on Friday morning that two substances found in Kronic Black would be banned from midnight tonight (Friday night), as well as another 12 others found in synthetic cannabis products.People caught in possession of banned synthetic cannabis face hefty fines or possible jail sentences.The government of Western Australia (WA) in June listed a number of synthetic cannabis products, including Kronic, Voodoo and Mango Kush, as illegal substances.But synthetic drug makers have since released a new product, Kronic Black Label, using a different blend of chemicals they say make it still legal to sell.Police suspect the death of a 38-year-old Perth man is linked to his smoking of the synthetic cannabis product Kronic Black Label, which contains two of the 14 substances to be banned.The man, from Hillman in Perth's south, was rushed to Rockingham Hospital on Thursday night after suffering a suspected cardiac arrest, but he later died.Police now are conducting an investigation to identify the cause of the man's death.The Australian Medical Association has warned that synthetic drugs could cause severe paranoia, anxiety and panic attacks.
LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.
WASHINGTON, July 12 (Xinhua) -- Two U.S. astronauts stepped out the International Space Station on Tuesday to retrieve a failed ammonia pump, which is the last spacewalk of the shuttle era, NASA announced.Space station astronauts Mike Fossum and Ron Garan completed the six-hour, 31-minute spacewalk at 3:53 p.m. EDT (1953 GMT). The duo retrieved a pump module from an external stowage platform on station and store it in shuttle Atlantis' cargo bay for return to Earth.The pump module failed in 2010, shutting down half of the space station's cooling system. Engineers will evaluate the module to determine the cause of the failure and plan to refurbish it for use as a spare.The astronauts also attached a Robotic Refueling Module experiment to the space station, which aims to test technologies for repairing and refueling satellites in space.It was the 249th spacewalk by U.S. astronauts and the 160th spacewalk in support of space station assembly and maintenance, totaling 1009 hours, nine minutes.Atlantis lifted off on Friday morning from Kennedy Space Center in Florida, on the 135th and final flight in NASA's shuttle program. Its return to the earth later this month will mark the end of the 30-year shuttle program.
WASHINGTON, July 18 (Xinhua) -- Exposure to secondhand smoke ( SHS) is associated with increased risk of hearing loss among adolescents, according to a report in the July issue of Archives of Otolaryngology -- Head and Neck Surgery.Among U.S. children, approximately 60 percent are exposed to SHS, according to background information in the article. Studies have associated exposure to secondhand smoke prenatally or during childhood with various health conditions, from low birth weight and respiratory infections to behavioral problems and otitis media. Children exposed to SHS are more likely to develop recurrent otitis media, the authors note. "Secondhand smoke may also have the potential to have an impact on auditory development, leading to sensorineural hearing loss (SNHL)," they add.Anil Lalwani and colleagues from New York University Langone Medical Center examined the risk factors for SNHL, including SHS, among adolescents, stratified by demographic groups. They included 1,533 individuals from 12 years to 19 years of age who participated in the National Health and Nutrition Examination Survey from 2005 to 2006.Participants were interviewed about their health status and family medical history, exposure to SHS, and self-recognition of hearing impairment. In addition, they underwent a physical examination, including blood testing for cotinine (a by-product of nicotine exposure), and hearing tests.Compared with teens who had no SHS exposure, those who were exposed to secondhand smoke exhibited higher rates of low- and high-frequency hearing loss. The rate of hearing loss appeared to be cumulative, increasing with the level of cotinine detected by blood tests. The results also demonstrated that more than 80 percent of participants with hearing loss did not realize they had impairment.As hearing loss early in life can cause problems with development and functioning, the authors suggest that these results have "significant implications for public health in the United States."They note that most adolescents do not receive screening for hearing loss in the absence of risk factors.If further studies replicate these results, they state, SHS could be considered one such risk factor.