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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906
CHICAGO – This past May, Harrisburg University won ESPN’s inaugural College Esports Championship. In 2018, the college became the first to award full-ride scholarships to its entire 16-player roster. With gaming programs expanding and an estimated million in esport scholarships up for grabs, elite players are finding themselves in high demand. Just ask 16-year-old Elgin, Illinois high school junior Jonathan Huffman. He’s been playing online since he was 13 and regularly spends hours at his bedroom gaming station. When asked how good a player he really is, Huffman wryly responds. “Very good. I don’t really say it too much but I’m one of the best in the world I would think,” he said. In fact, Huffman is so good he needs a live camera trained on his hands during gameplay streaming to prove to others he’s not hacking the system. “Whenever people accuse me, they just look at the hand-cam and it kind of fixes the issue,” he said. Huffman’s game of choice is Overwatch. Online he’s known as “MyCrazyCatOW.”He regularly ranks among the top 50 competitive players in the world. As a result, colleges and universities are clamoring to recruit players like him. “To give an analogy – like in professional basketball he’s up there in the echelons of the Steph Currys, the Lebron Jameses of the world,” explained Alan Gadbois. Gadbois is a recruiter for Next College Student Athlete the official recruiting partner of the 1443
Two sets of human remains found in the backyard of Chad Daybell's property have been confirmed to be those of JJ Vallow and Tylee Ryan.According to a news release Saturday from the Rexburg Police Department in Idaho, the medical examiner's office confirmed their identities after performing an autopsy.Earlier this week, family members said in a statement that they were informed the remains were JJ and Tylee, who were reported missing last year. J & Tylee are gone, Joshua Vallow's grandparents confirm. #JJVallow #TyleeRyan pic.twitter.com/XGPNMbK7U0— Marc Sternfield (@msternfield) June 10, 2020 Police said Wednesday that two bodies were found Tuesday on Daybell's Idaho property during the execution of a search warrant. An official cause of death hasn't been released. The children's grandparents released a statement saying the family was "filled with unfathomable sadness" and could confirm that the bodies were JJ and Tylee. Daybell was taken into custody Tuesday and appeared in court Wednesday when a judge set a million bail. He is currently jailed on charges of “destruction, alteration or concealment of evidence."A prosecutor said during Wednesday's initial court appearance that they were aware the remains were that of children, but at that time officials had not yet fully identified them. Lori Daybell, Chad's current wife, has remained in jail on a million bail as authorities continued the search for JJ and Tylee. She has been in jail since February.Authorities in Arizona had also been investigating two deaths tied to the case -- Lori Daybell's fourth husband, Charles Vallow, as well as her brother, Alex Cox. This story was written by KNXV Staff. 1733
LACKLAND AFB, Texas – The Centers for Disease Control has now confirmed a 15th case of the new coronavirus, officially named COVID-19, in the United States. Thursday, the CDC said the new patient was among a group of people under federal quarantine at JBSA-Lackland in Texas who recently returned to the U.S. from China on a State Department-chartered flight that arrived on Feb. 7. This is the first person under quarantine at JBSA-Lackland who had symptoms and tested positive for COVID-19, according to the CDC. The new patient is currently isolated and receiving medical care at a designated hospital nearby. This isn't the first case of an evacuee being diagnosed with COVID-19. The 13th and 14th cases of the virus were found among evacuees who were flown last week from Wuhan to Marine Corps Air Station Miramar in Southern California. This newest COVID-19 case was the first confirmed in Texas. The other 14 cases have been confirmed in California, Illinois, Massachusetts, Washington state, Arizona and Wisconsin.Health officials say there will likely be additional COVID-19 cases in the coming days and weeks, including people who recently returned from Wuhan. While 195 people were discharged from quarantine on Tuesday, more than 600 people who returned on chartered flights from Wuhan remain under federal quarantine and are being closely monitored to contain the spread of the virus.In China, the government said Thursday that more than 59,800 people have been infected with the virus and the country’s death toll has risen to 1,367, 1564
Megan and Fadil Lee's love story started when the two were freshmen in college, and it may have ended there had Fadil not sent Megan a Facebook message 25 years later. “I was like, OK, is he single or married?” Megan recalls. After dating for a year and a half, the two married, and Fadil wanted to be a first-time father. Megan was on board, despite being 45 years old and already having two adult kids. “Let's face it; we're all living longer, you know,” Megan says. “And I don't think that age should be an inhibitor for you if you're in good health and you're in good shape. I think that those options should be available to you.”Dr. Paul Magarelli, who specializes in fertility for older women, agrees. “Now that we're living to 80, 90 and 100, the idea of a baby at 50 really is not that crazy,” he says. Dr. Magarelli is helping the couple conceive through IVF. “The uterus doesn't age; it’s a muscle. So, they've done successful IVF and women with donor egg up to age 74 and still got healthy babies,” Dr. Magarelli says. Megan is planning to use her own eggs, but the reality is most older women use frozen or donor eggs. “Once you reach the age of 44 and above the number of eggs that are available to make a baby are preciously few, so most families at some point will use donor eggs,” Dr. Magarelli says. There are significant risks for both mother and baby, including gestational diabetes, pregnancy-induced hypertension, as well as pregnancy loss. Babies also have a higher risk of chromosome abnormalities, such as Down syndrome. Megan and Fadil say they are aware of the risks and are being proactive. “We are going to do genetic testing on the embryos because of our age,” Megan says. “So, we want to make sure that all the chromosomes are supposed to be there are there in full and complete.” These come along with a hefty price tag. Standard IVF treatments can cost anywhere from ,000 to ,000. Paying out of pocket for the procedure, the couple hopes everything goes right on their first try.“We both have a very strong faith, and so if stuff doesn't work out, then we're going to look at that as a sign from God that we're just not supposed to be parents at this stage in our life,” she says. 2232