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2025-05-24 05:33:36
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  梅州瘦身吸脂术   

SAN DIEGO (KGTV) -- Crews were able to extinguish a fire in Clairemont Friday afternoon reportedly started by a crash. According to California Highway Patrol, the blaze started on Boyd Avenue near Genesee Avenue. San Diego Police say at 5:24, a suspect hit several vehicles on Balboa and Mount Alifan Drive before taking off. RELATED: Check today's San Diego County forecastThe suspect then lost a tire, creating sparks and starting the blaze. The suspect was later taken into custody. The fire sparked just as a Red Flag Warning in parts of San Diego County was allowed to expire. 590

  梅州瘦身吸脂术   

SAN DIEGO (KGTV) — As Americans wait for a regulatory decision on Pfizer’s COVID-19 vaccine candidate, local dry ice companies are counting on the cold chain distribution to help boost sales that have significantly dried up during the pandemic.San Diego Ice Company in the Midway District said it is already fielding calls from hospitals and clinics looking to order dry ice. The family-owned business has distributed ice products for decades, but vice president Anthony Toma said the company has secured the equipment needed to begin manufacturing dry ice from liquid carbon dioxide in December.“Without this dry ice, there's no vaccine,” Toma said.Dry ice is carbon dioxide in its solid form. It’s critical to shipping and storing Pfizer’s COVID-19 vaccine candidate.While Moderna’s vaccine can be stored in a standard freezer, Pfizer’s candidate needs to be kept at 94 degrees Fahrenheit below zero. That’s colder than winter in Antarctica.The company says once it gets the green light from the FDA, it will pack vials in boxes with dry ice. Each shipper box can hold up to 5,000 doses and will be fitted with sensors to constantly track location and temperature.Pfizer will ship the boxes from sites in Kalamazoo, MI and Pleasant Prairie, WI via FedEx and UPS, sending them to hospitals, clinics and pharmacies across the country.From there, vaccination providers must store the doses in a way that preserves their efficacy. Long-term storage of up to six months requires an ultra low-temperature freezer, but outside of hospitals those units are rare.The cold chain required for Pfizer’s candidate is “the most challenging issue” facing distribution, Governor Gavin Newsom said Monday.Newsom said the state plans to assist Pfizer’s efforts by purchasing 16 ultra low-temperature freezers, along with 61 smaller freezers that will be positioned in high-need areas.Another storage option is to keep doses in Pfizer’s thermal shipper box. Vials can last in the box for up to 15 days be refilling the dry ice, and Toma expects some of his dry ice will be part of that process.“We're gonna play a big part,” he said. “We're ready for that and we're honored to do it.”Toma is hoping dry ice will help thaw sales that have plummeted because of the pandemic. A lot of the ice business relies on big events and conventions that have been shut down. Restaurants have reduced volume. Airlines have cut back on food service.“There are a couple of [ice] companies that I spoke with and they said, ‘If it wasn't for dry ice, we wouldn't know what to do,’” he said. “Dry ice is keeping most of us alive.”Toma knows the implications aren’t just financial. Both he and his wife caught the virus and recovered, so they know just how important these vaccines are.Starting in December, San Diego Ice Company will start producing about 1800 pounds of dry ice an hour, he said. That’s enough to fill 36 of Pfizer’s shipper boxes, which require 50 pounds of dry ice each.The FDA has scheduled a meeting of its vaccine advisory committee on December 10. The agency is expected to announce a decision on whether to approve an emergency use authorization shortly thereafter. 3161

  梅州瘦身吸脂术   

SAN DIEGO (KGTV) — As the world waits for a vaccine against the coronavirus, two San Diego biotechs are teaming up to develop a nasal spray using designer antibodies cloned from COVID-19 survivors.About 70 companies worldwide are working on therapies for COVID-19 using cloned antibodies, according to an estimate by the International AIDS Vaccine Initiative. A few of these treatments, known officially as monoclonal antibody therapies, have advanced to clinical trials.Most require an injection, but San Diego-based Diomics and its partner Active Motif, based in Carlsbad, are developing a once-a-day spray that could be easily self-administered.Early research suggests the coronavirus primarily enters the body through the nose. The spray, called Dioguard, is designed to coat the lining of the nasal cavity with cloned antibodies that are held in place for 24 hours or more using a proprietary polymer material developed by Diomics.Diomics CEO Anthony Zolezzi said he believes the spray “holds the key to allowing many aspects of life to resume until the day comes when there’s an effective vaccine in widespread use.”Diomics is also developing two tests for COVID-19 antibodies using its polymer beads, including a device that looks like a nicotine patch that is designed to monitor for infections for a week or more.RELATED: How a dot on your forearm could be the future sign of COVID immunityActive Motif is providing the cloned antibodies for the nasal spray. With a lab in Shanghai and other relationships in China, the Carlsbad company was able to clone antibodies from 11 Chinese survivors in February, before the World Health Organization declared a pandemic.When the company started the cloning project, they thought the virus would probably disappear in three to six months, said Active Motif CEO Ted DeFrank. “Then people started realizing, no this is going to be with us for a while.”The plasma from the 11 Chinese patients contained thousands of antibodies, and scientists with Active Motif set about selecting the one that was most effective, dubbed 414-1. The company says it can neutralize SARS-CoV-2 virus particles with 98 percent effectiveness.Monoclonal antibodies have some similarities to convalescent plasma, which is a complex cocktail of antibodies and other immune molecules drawn from the blood of recovered patients. One of the key differences is that cloned antibodies can be mass produced in a lab.Cloned antibodies have been used in treatments for more than 30 years, primarily for cancer. One such treatment famously helped former U.S. President Jimmy Carter beat melanoma.But of the more than 100 monoclonal antibody therapies licensed for use, only seven are for communicable diseases, according to IAVI.Historically, the treatments have been expensive and difficult to produce, but Diomics said it’s targeting a price of about a spray for Dioguard, roughly per bottle.“We do not want to have huge profits from a pandemic, that’s just wrong,” Zolezzi said. “We’re going to price this as effectively as we can for the masses. We want to get this out to the masses.”Animal testing is about to begin and the companies said they hope to progress to human trials soon. Their goal is to release the spray in early 2021, when a vaccine may be on the market but not yet widely available.If the spray works, it could be adapted to other viruses to help fight future pandemics, Zolezzi said."That’s our real goal," Zolezzi said. "That we never get caught flat-footed like this time." 3526

  

SAN DIEGO (KGTV) -- As the world outside continues to change in drastic and dramatic ways, it’s easy to feel stuck in stress and despair.ABC/10News anchor Kimberly Hunt speaks with a Holocaust survivor who has devoted her life to inspiring others to change the imprisoning thoughts and destructive behaviors that may be holding us back.Dr. Edith Eger’s empowering conversation helps us see our darkest moments as our greatest teachers. She says true freedom only comes when we confront the past, as well as this pandemic, with strategies and tools for finding the gift in every day. It’s an investment in the future, the conviction to focus not on what we’ve lost, but on what’s still here.She’s also written lessons for breaking out of personal prisons in order to live a full life in her new book: The Gift. Click here for more information. 851

  

SAN DIEGO (KGTV) -- As we cast our ballots in this year's election, it's a good time to reflect on how our freedom to vote came at a cost. A member of the Greatest Generation looks back at how he and his fellow service members risked their lives to preserve that freedom and how his love for America began about 90 years ago.It started in North Carolina in the 1930s during the Great Depression. Forrest "Huff" Huffstetler, 96, says, "I remember how people suffered back then and I remember people lining up to get a bowl of soup."Despite the hardship, he remembers his life growing up on a farm fondly."We had our own pigs, fresh vegetables and we had cans. My mother and my grandmother would can all the food for us for the winter. We had it pretty good."It's that optimism that motivated Huff to make a decision that would change his life."I was delivering newspapers at 4 o'clock in the morning and that's when the post office had out a picture of Uncle Sam pointing a finger at you."The poster he saw encouraged people to enlist. He says his instant reaction was, "Man this is a good deal, I'd like to get in the Army."He was 15 and a half years old. He managed to enlist by convincing the notary public, who was also his aunt, that he was 18. He says it was well worth it. "I loved the Army. We had three meals a day, I had all my clothes given to me and I wanted nothing. It was wonderful."For more a month, Huff signed on to become a paratrooper with the 82nd Airborne Division. After two tours of duty came D-Day and that defining moment, the jump over Normandy. He remembers seeing the tens of thousands of service members around him."There were paratroopers everywhere and ships out in the channel, there in the channel as far as you could see."The first town Huff helped liberate was Sainte-Mere-Eglise, which explains the hero's welcome back he received last year on the 75th anniversary of D-Day. He looks back at the unity in their fight for freedom back then and says it makes him sad to see people divided today."It breaks my heart. All these men died fighting for this country," he says, "Freedom doesn't come for free, there's nothing for free."That's why Huff votes."I remember the first time I ever voted was when I came out of the service. I was 21 years old, and it was an honor for me to go vote," he says.He wants everyone to exercise that freedom and says he also thinks things will get better. "Things are going to change. We're going to get our country back together working together." After his service, Huff worked in the restaurant industry including owning a restaurant for 20 years. He eventually made a home in San Marcos. In December, Huff will turn 97 years old. 2717

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