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BEIJING, May 30 (Xinhuanet) -- Chronic diseases, including heart disease, stroke, cancer, chronic respiratory diseases and diabetes, are the leading cause of mortality in China, representing 85 percent of all deaths, said a senior health official.Kong Lingzhi, deputy director of the disease prevention and control bureau under the Ministry of Health, made the remarks on Saturday at the Forum of Prevention and Control of Chronic Disease."China is facing a great challenge from chronic diseases, which has a serious impact on both the economy and society," said Kong.Each year, about 3.7 million people die before they reach 60 because of chronic diseases. There are currently 200 million hypertension patients and 90 million diabetics in China, official statistics show.To address the challenge, "the government is now drafting an inter-ministerial roadmap for chronic disease intervention, which will set targets, define responsibilities and distribute guidelines for the prevention and control of chronic diseases," she said.The initiative aims to strengthen national and global monitoring and surveillance; scale up the implementation of evidence-based measures to reduce risk factors, such as tobacco use, an unhealthy diet, physical inactivity and harmful alcohol use; and improve access to cost-effective healthcare to prevent complications, disabilities and premature death.But more importantly, the roadmap will help gain attention and support for preventing and controlling chronic diseases and place it high on government working agendas, Kong explained.The government has focused more on addressing instant health crises up to now and policy and funding support for chronic disease control and prevention was very limited, admitted Mao Qun'an, spokesman of the ministry.Given that chronic disease control requires a systematic approach, tasks such as public health education, training for medical workers (especially the grassroots ones) and policies encouraging doctors' involvement need to be carried out, he said.The ultimate goal is to prevent people from getting ill rather than treating diseases, he added.Lei Zhenglong, deputy director of the disease prevention and control bureau, said that to enhance the capacity of medical workers was now the top priority for the initiative.At present, effective disease prevention work usually contradicts the financial interests of clinical doctors, analysts said.A respiratory disease doctor surnamed He with the Peking University People's Hospital said that he came under pressure from the hospital authorities when the number of inpatients declined due to his efforts to inform his patients about chronic disease prevention.

WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.

WASHINGTON, July 13 (Xinhua) -- Human neural stem cells are capable of helping people regain learning and memory abilities lost due to radiation treatment for brain tumors, a University of California, Irvine (UCI) study suggests.Research with rats found that stem cells transplanted two days after cranial irradiation restored cognitive function, as measured in one- and four-month assessments. In contrast, irradiated rats not treated with stem cells showed no cognitive improvement."Our findings provide solid evidence that such cells can be used to reverse radiation-induced damage of healthy tissue in the brain," said Charles Limoli, a UCI radiation oncology professor.Study results will appear Friday in Cancer Research, a journal of the American Association for Cancer Research.Radiotherapy for brain tumors is limited by how well the surrounding tissue tolerates it. Patients receiving radiation at effective levels suffer varying degrees of learning and memory loss that can adversely affect their quality of life."In almost every instance, people experience severe cognitive impairment that's progressive and debilitating," Limoli said. " Pediatric cancer patients can experience a drop of up to three IQ points per year."For the UCI study, multipotent human neural stem cells were transplanted into the brains of rats that had undergone radiation treatment. They migrated throughout the hippocampus -- a region known for the growth of new neurons -- and developed into brain cells.Researchers assessed the rats one month and four months after transplantation, noting enhanced learning and memory abilities at both intervals.Additionally, they found that transplanting as few as 100,000 human neural stem cells was sufficient to improve cognition after cranial irradiation. Of cells surviving the process, about 15 percent turned into new neurons, while another 45 percent became astrocytes and oligodendrocytes -- cells that support cerebral neurons.Most notably, Limoli said, he and his colleagues discovered that about 11 percent of the engrafted cells expressed a behaviorally induced marker of learning, indicating the functional integration of those cells into memory circuits in the hippocampus."This research suggests that stem cell therapies may one day be implemented in the clinic to provide relief to patients suffering from cognitive impairments incurred as a result of their cancer treatments," Limoli said.

WARSAW, June 2 (Xinhua) -- A possible second E. coli infection patient has been hospitalized in Szczecin, northwestern Poland, Health Minister Ewa Kopacz said Thursday.The man, who recently returned to Poland from Germany, has been diagnosed with exudative diarrhea and is currently being tested for E. coli bacteria.Poland's first E. coli case, a 29-year-old woman permanently residing in Germany and diagnosed with the bacteria over a week ago, is currently in the same hospital.Kopacz said sanitary teams were running E. coli checks countrywide, especially on marketplaces and in warehouses.The E. coli epidemic originated in Germany, where it has taken 17 lives. One death has so far occurred in Sweden, bringing the total death toll to 18.

WASHINGTON, July 5 (Xinhua) -- The countdown for the final space shuttle launch began Tuesday afternoon, but unfavorable weather may delay shuttle Atlantis' launch attempt on Friday, NASA announced."We are going with a 60 percent chance of KSC (Kennedy Space Center) weather prohibiting launch due to the potential for showers and isolated thunderstorms in the area," shuttle weather officer Kathy Winters told reporters Tuesday at a precountdown status briefing. "I wish I had a better weather briefing for you."Atlantis is scheduled to lift off at 11:26 am (1526 GMT) on Friday from Kennedy Space Center with four U.S. astronauts on board for a 12-day mission to the International Space Station. Overall, the chance of an on-time liftoff is 40 percent, Winters said."We will do everything we can to launch on Friday but if things don't work out so that we can do that we have plenty of options... Saturday and Sunday," said NASA Test Director Jeremy Graeber. Conditions improve for Atlantis launch opportunities on Saturday and Sunday.NASA said it must launch Atlantis by Sunday, otherwise it will have to wait until at least July 16. That's because of an unmanned rocket due to lift off next week, using the same launch support personnel and equipment.NASA's 30-year-old shuttle program is ending due to high operating costs. The Obama administration wants to spur private companies to get into the space taxi business, freeing NASA to focus on deep space exploration and new technology development.When the U.S. space shuttle program officially ends later this year, the Russian space program's Soyuz capsule will be the only method for transporting astronauts to and from the station.