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BEIJING, August 4 (Xinhuanet) -- Medtronic Inc. is giving Yale University a 2.5 million U.S. dollar grant to review the safety and effectiveness of its controversial spine treatment called Infuse Bone Graft, according to The Wall Street Journals Thursday.Under terms of the pact, the company will release to Yale and eventually the public what participants described as an unprecedented amount of clinical trial and other data. The university will select two research teams from other organizations to perform separate analyses of the data.The announcement comes in the wake of a paper in June in the Spine Journal. The paper revealed that several clinical studies of Infuse, conducted by surgeons with strong economic ties to Medtronic, failed to report serious complications that arose in the trials. The critical paper also found that many of the studies were designed in ways in favor of Infuse over a treatment given to a control group.Medtronic disputes some of the findings and is conducting an internal investigation of the matter.Infuse accounts for about 700 million dollars in annual sales for Medtronic. The product is under investigation by the Senate Finance Committee over the role payments to physicians who may have played how studies were reported.

BEIJING, July 6 (Xinhua) -- The Ministry of Health has issued a national standard on compound food additives to better regulate the production and use of such additives and ensure food safety.Compound food additives, which are designed to improve food quality or assist in food processing, should be used sparingly in food products, according to the standard the ministry issued Tuesday.Titled the General Rule on Compound Food Additives, the standard stipulates that each of the ingredients used for making compound food additives, which are a mix of two or more single food additives, should meet national standards concerning food safety.No chemical reaction should occur and no new compounds should be generated during the production process of compound food additives, according to the standard.Compound food additives producers should clarify limits of the amounts of harmful substances, such as lead and arsenic, in their products and take measures to control the levels of harmful substances, according to the standard, which will come into effect on Sept. 5 this year.

WASHINGTON, June 14 (Xinhua) -- Eating a low-carbohydrate, high- protein diet may reduce the risk of cancer and slow the growth of tumors already present, according to a study published Tuesday in Cancer Research, a journal of the American Association for Cancer Research.The study was conducted in mice, but the scientists involved agree that the strong biological findings are definitive enough that an effect in humans can be considered."This shows that something as simple as a change in diet can have an impact on cancer risk," said lead researcher Gerald Krystal, a scientist at the British Columbia Cancer Research Center.Krystal and his colleagues implanted various strains of mice with human tumor cells or with mouse tumor cells and assigned them to one of two diets. The first diet, a typical Western diet, contained about 55 percent carbohydrate, 23 percent protein and 22 percent fat. The second, which is somewhat like a South Beach diet but higher in protein, contained 15 percent carbohydrate, 58 percent protein and 26 percent fat. They found that the tumor cells grew consistently slower on the second diet.As well, mice genetically predisposed to breast cancer were put on these two diets and almost half of them on the Western diet developed breast cancer within their first year of life while none on the low-carbohydrate, high-protein diet did. Interestingly, only one on the Western diet reached a normal life span ( approximately 2 years), with 70 percent of them dying from cancer while only 30 percent of those on the low-carbohydrate diet developed cancer and more than half these mice reached or exceeded their normal life span.Krystal and colleagues also tested the effect of an mTOR inhibitor, which inhibits cell growth, and a COX-2 inhibitor, which reduces inflammation, on tumor development, and found these agents had an additive effect in the mice fed the low-carbohydrate, high-protein diet.When asked to speculate on the biological mechanism, Krystal said that tumor cells, unlike normal cells, need significantly more glucose to grow and thrive. Restricting carbohydrate intake can significantly limit blood glucose and insulin, a hormone that has been shown in many independent studies to promote tumor growth in both humans and mice.Furthermore, a low-carbohydrate, high-protein diet has the potential to both boost the ability of the immune system to kill cancer cells and prevent obesity, which leads to chronic inflammation and cancer.

WASHINGTON, Sept. 13 (Xinhua) -- The U.S. Department of Agriculture (USDA) announced Tuesday it will begin testing next year for six more kinds of E.coli bacteria in raw ground beef and tenderized steaks in order to protect the safety of the American food supply.The U.S. currently tests for one strain of E.coli O157:H7 in beef. According to the USDA, from March 5 next year, if the E. coli serogroups O26, O103, O45, O111, O121 and O145 are found in raw ground beef or its precursors, those products will be prohibited from entering commerce.Like E.coli O157:H7, these serogroups can cause severe illness and even death, and young children and the elderly are at highest risk."The Obama Administration is committed to protecting our food supply and preventing illnesses before they happen," said Agriculture Secretary Tom Vilsack in a statement. "Today's announcement does exactly that by targeting and eliminating contaminated products from the market.""Too often, we are caught reacting to a problem instead of preventing it. This new policy will help stop problems before they start," he said.About one in six Americans becomes sick from a food borne illnesses each year, an epidemic that kills about 3,000 annually and hospitalizes 128,000, according to the U.S. Centers for Disease Control and Prevention.

来源：资阳报