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This is really a law for people who are very sick, who have exhausted all treatment options and who cannot enroll in a clinical trial, said Starlee Coleman, senior policy adviser at the Goldwater Institute, a conservative public policy think tank based in Phoenix that supports right-to-try legislation."For people living in a state where right-to-try is already on the books, they already have the ability today to work with their doctors directly to approach a drug company with a drug in clinical trials and ask for the option to try that drug outside of the clinical trial," she said. "For people living in the 12 states without a right-to-try law, today they don't have this option, but if the federal law passes, they will have the option."Some opponents argue that the bill won't change much but could have a detrimental effect on how the FDA safeguards the health of the public.Dr. Steven Joffe, professor in medical ethics and health policy at the University of Pennsylvania's Perelman School of Medicine, co-authored a perspective paper about such concerns, published in the New England Journal of Medicine last month.The paper notes that the FDA already has expanded-access policies, sometimes called compassionate use, to give terminally ill patients without other options access to investigational medical products outside of clinical trials.About 99% of submitted applications for expanded access to almost 9,000 investigational drugs were allowed to proceed over a 10-year period between January 2005 and December 2014, according to a study by FDA researchers, published in the journal Therapeutic Innovation & Regulatory Science in 2016."Emergency requests for individual patients are usually granted immediately over the phone and non-emergency requests are generally processed within a few days," FDA Commissioner Dr. Scott Gottlieb said in a statement last year. 1885

Trump has long denied any collusion between his campaign and Russian operatives during the 2016 election. But US intelligence agencies concluded in a report released earlier this year that Russia ordered an "influence campaign" to harm Hillary Clinton's chances of winning the election. 286
There's a common theme in the news coming out of this White House this week, said Nathan Click, spokesman for Newsom. "The President is abusing the powers of the presidency and weaponizing government to attack his political opponents. This is not about clean air, clean water or helping our state with homelessness. This is political retribution against California, plain and simple." 384
their interest rate policy, preferring to watch as the economy evolves.Powell has tried to caution investors not to read too deeply into the so-called dot plots, which includes forecasts of each member of the policy-setting committee on where they anticipate interest rates will go.At the March meeting, Fed officials downgraded their GDP growth forecast for 2019 to 2.1%, suggesting they may be more worried than previously about slowing domestic and global growth. The slowdown in China, driven in part by an ongoing trade war sparked by President Donald Trump, as well uncertainty surrounding Brexit, threaten the global economy.Central bankers previously estimated the US economy would grow 2.3% this year, significantly lower than the Trump administration's forecast.They also raised their estimates of the country's jobless rate to 3.7% up from 3.5%.The bank also officially laid out plans to end its trillion balance sheet normalization on a monthly basis.Starting in May, the Fed will begin to address its holding of Treasury securities by reducing the cap from the current level of billion to billion per month.Then, at the end of September, the Fed will effectively stop undoing the extraordinary steps it took to prop up the economy for almost a decade after the financial crisis. Fed officials, including Powell, had signaled the Fed would probably take such a step later this year, but no date had been previously set. 1442
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