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Reporting on data from a Phase II trial of the vaccine, the authors write that volunteers in the trial demonstrate similar neutralising antibody titres and T cell responses across all three age groups of 18-55, 56-79, and 70+. pic.twitter.com/8oBZNJEBTn— University of Oxford (@UniofOxford) November 19, 2020 316
President Donald Trump told lawmakers on Thursday he was scrapping a planned pay raise for civilian federal workers, saying the nation's budget couldn't support it.In a letter to House and Senate leaders, Trump described the pay increase as "inappropriate.""We must maintain efforts to put our Nation on a fiscally sustainable course, and Federal agency budgets cannot sustain such increases," the President wrote.An across-the-board 2.1% pay increase for federal workers was slated to take effect in January. In addition, a yearly adjustment of paychecks based on the region of the country where a worker is posted -- the "locality pay increase" -- was due to take effect.Trump said both increases would no longer happen."I have determined that for 2019, both across the board pay increases and locality pay increases will be set at zero," he wrote.He stressed the change wouldn't affect the federal government's ability to attract qualified workers, and wrote the government would focus on "recruiting, retaining and rewarding high-performing Federal employees and those with critical skill sets."The implications of Trump's decision on the locality pay increase were not immediately clear. Workers based in more expensive parts of the country are paid higher salaries to compensate for the higher cost of living.In his letter, Trump wrote the locality increase in 2019 would average 25.70% and cost the federal government billion. But he did not say whether the locality adjustments already in place would remain in effect and the White House did not immediately clarify.Pay for military personnel will not be affected by Trump's decree; instead, US troops are due a 2.6% pay increase next year. Trump frequently trumpets the military pay raise while listing his administration's accomplishments. The raise came as part of a massive 6 billion defense spending bill that Trump signed earlier this month.That measure, along with a new two-year federal budget and tax cuts heralded by Republicans, have led to accusations Trump is ignoring the federal deficit, despite promising he would address it as president. The tax plan alone is expected to increase the deficit by .4 trillion over 10 years, according to a government estimate.Reaction from Democrats was swift, particularly those from states adjacent to Washington, where large numbers of federal workers reside."Zero. This seems to be how much respect President Trump has for federal workers," wrote Sen. Ben Cardin, D-Maryland, in a statement. "It is outrageous and hypocritical that after spending billions of taxpayer dollars on unnecessary tax cuts for the wealthy and big corporations -- and as the President boasts about the 'great' state of the American economy, that suddenly the White House finds that there is zero money left to pay a minimal cost-of-living adjustment to the patriotic, dedicated public servants."While the Washington area contains the largest concentration of federal workers, only 1-in-6 civilian employees of the government live in the region.The state with the largest number of federal workers is California, followed by Virginia, Washington, DC, and Texas. 3164

Residents of a hospice in London woke up Sunday to a pleasant and sweet-smelling surprise: the flowers that surrounded the Duke and Duchess of Sussex on their wedding day.The donated flowers, which adorned both St. George's Chapel and St. George's Hall in Windsor on Saturday, were designed by Philippa Craddock and a team of florists from Buckingham Palace and Windsor Castle.The bouquets were made up of foxgloves, peonies, and white garden roses, many of which were sourced from the gardens and parkland of the royal-owned Crown Estate and Windsor Great Park.Kensington Palace confirmed that the flowers were donated to a number of charities and hospices. One recipient was St. Joseph's in Hackney, east London. "To see the faces of the patients when they received the flowers was just fantastic," hospice spokeswoman Claire Learner told CNN.St Joseph's has a long history of royal connections, having been visited by Queen Elizabeth II, Princess Diana and, most recently, Prince Edward, who toured the grounds in 2015, the hospice said.The ties to the royal family do not stop there. Pauline Clayton, an 89-year-old patient, once worked as an embroideress to Norman Hartnell, one of the Queen's dressmakers.She revealed that aged just 19, she worked for almost 50 hours on the train of the Queen's own wedding dress, according to the UK's Press Association.Clayton added that she thought the gesture to donate the flowers was "lovely."For Father Peter-Michael Scott, the hospice's lead chaplain, the gesture signified something altogether more fundamental."It is about the energy of love. We are absolutely thrilled by the flowers and wish them (Harry and Meghan) all the best for the future," he also told PA. 1732
President Donald Trump’s physical Dr. Sean Conley confirmed Friday that the president is taking an experimental antibody treatment to help him fight the coronavirus following his diagnosis this morning.Dr. Conley said Friday afternoon that Trump is "fatigued."Trump is taking the Regeneron antibody cocktail, which is currently in a clinical trial. Conley said that Trump has been treated with a single 8 gram dose, which Conley said was infused "without incident."Trump is also said to be taking Vitamin D, zinc, famotidine, melatonin and daily aspirin. The Regeneron trial has only been tried on 275 patients as of this week, but the company said earlier this week that it has showed promising results.Regeneron confirmed that Trump was given the treatment under a "compassionate use request.""In the USA, this type of compassionate use program is also known as an Expanded Access Program (EAP) and is intended for patients with serious or life-threatening conditions, who do not have any viable or available treatment options, and are unable to participate in ongoing clinical trials," Regeneron said in a statement. The plan is to enroll 2,000 patients in early studies of the treatment."After months of incredibly hard work by our talented team, we are extremely gratified to see that Regeneron's antibody cocktail REGN-COV2 rapidly reduced viral load and associated symptoms in infected COVID-19 patients," said George D. Yancopoulos, M.D., Ph.D., President and Chief Scientific Officer of Regeneron. "The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response. These patients were less likely to clear the virus on their own, and were at greater risk for prolonged symptoms.The treatment is a combination of two monoclonal and was designed specifically to block infectivity of SARS-CoV-2, the virus that causes COVID-19, the company said.“The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.” Regeneron said in a statement. “Preclinical studies have shown that REGN-COV2 reduced the amount of virus and associated damage in the lungs of non-human primates.”According to Regeneron, the treatment has been tried on hospitalized and non-hospitalized patients and as a preventative for those who have had close contact with coronavirus patients. So far, the drug has been particularly promising for non-hospitalized patients.Regeneron said the treatment reduces the viral load from the coronavirus, and boosts the body’s immune response to the virus. 2890
Rebecca Luker was one of the most beautiful voices on Broadway and a lovely person ,,We are all devastated for Danny and for ourselves,,we will never get to witness her talents on stage again ????????RIP Dear Dear Girl?? pic.twitter.com/6qSKhEZZ2c— Bernadette Peters (@OfficialBPeters) December 23, 2020 320
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