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WELLINGTON, May 24 (Xinhua) -- New Zealand researchers have found a way to stop the growth of certain cancer tumors by " silencing" a group of PAX genes, members of a small family of genes that play important roles in embryonic development, but also allow cancer cells to grow and divide in adult tissue.In an article published in UK medical journal Oncogene, Otago University Professor Michael Eccles and colleagues revealed how they used the PAX8 gene to kill cancer cells.After detecting high levels of PAX8 protein in the majority of kidney, ovarian and thyroid cancers they studied, the researchers used molecular techniques to silence the PAX8 gene in several cancer cell lines."We found that these PAX8-depleted cancer cells ceased growing and dividing. The cells were essentially stopped in their tracks through the failure of multiple mechanisms and pathways crucial to their cell division cycle. They then entered into a state called senescence in which they no longer divided, and after that they ultimately died," Eccles said in a statement from the university Tuesday.The findings suggested that PAX8 could be a good target for the development of new cancer therapies, he said."Any resulting drugs would be a long way down the road, but in the meantime this research helps confirm that a focus on PAX genes may prove to be a fruitful line of attack against a number of cancers," he said.The research was supported by grants from the Health Research Council of New Zealand. It formed the main piece of work carried out by Otago doctoral graduate Caiyun (Grace) Li, now a postdoctoral fellow at Stanford University. Study co-authors also included Professor Antony Braithwaite and master's student Jen Nyman.In 2003, research led by Eccles discovered that proteins from one or more of the nine PAX genes were present in many common cancers. They found that "silencing" the gene expression of PAX2 in ovarian and bladder cancer cells, and of PAX3 in melanoma, led to the rapid death of the cells.
SAN FRANCISCO, April 27 (Xinhua) -- Apple Inc. on Wednesday denied the alleged location-tracking practice of its mobile operating system, saying it will release software updates to make iPhone store less location information to quell public concerns over privacy.CLARIFICATION"Apple is not tracking the location of your iPhone. Apple has never done so and has no plans to ever do so," the company said in a statement."Users are confused, partly because the creators of this new technology (including Apple) have not provided enough education about these issues to date."According to the statement, the location data researchers saw on iPhone is a database of Wi-Fi hotspots and cell towers around users' current location that Apple is maintaining to help iPhone rapidly and accurately calculate its location when requested. It noted Apple cannot locate iPhone users based on Wi-Fi hotspot and cell tower data as the information is in an anonymous and encrypted form.Apple admitted that part of the location data (Wi-Fi hotspots and cell towers) is backed up on iTunes, which means it could be possible that people with access to iPhone users'computer may get their location information. It said a software update has been planned to cease the backing-up.It is also planning to provide an update to limit the data storage on iPhone, in response to questions that the device has been storing location data since the release of iOS 4 operating system last June.Apple said it is a bug that iPhone keeps storing location data even if its location services are disabled, noting it will fix this through a software update in the coming weeks.The company also reiterated its focus on personal information security and privacy."Pretty much what I expected at this stage. The response is measured and the update should fix the problem," Alasdair Allan, one of the two British researchers who first announced the discovery of stored location data on iPhone, said on his Twitter account.ALLEGATIONThe statement on Wednesday is Apple's first official response to the location-tracking allegations.Worries on the iPhone tracking issue first surfaced last Wednesday when two British researchers announced at a technology conference in California that iPhone has been collecting users' location information and storing the data since June 21, 2010.Last Friday, The Wall Street Journal reported its security analysts had found that Apple's iPhone and smartphones running Google's Android operating system regularly transmit users' locations back to the two companies respectively, which is part of their race to build databases capable of pinpointing people's locations via smartphones.The newspaper then reported on Sunday that its analysts had also found iPhone is collecting and storing user's location data even when location services are turned off.PRESSUREThe Cupertino, California-based company has been facing mounting pressure from lawmakers, customers as well as media reports following the revelations.The U.S. House Energy and Commerce Committee on Monday sent letters to six developers of mobile device operating systems, including Apple and Google, demanding Apple's explanation on implications of alleged tracking for individual privacy and federal communications policy.Also on Monday, Minnesota Senator Al Franken, chairman of the U. S. Senate Judiciary Subcommittee on Privacy, Technology and the Law, announced he had scheduled a mobile privacy hearing on May 10 and asked representatives from Apple and Google to speak at the hearing.Meanwhile, Lisa Madigan, Attorney General of U.S. state of Illinois, on Monday called for a meeting with Apple and Google executives on the location-tracking reports, citing her ongoing effort to protect consumers' personal information online.Last Friday, two iPhone users filed a class action suit against Apple in Tempa, Florida, accusing the company of invasion of privacy and computer fraud and seeking a judge's order to bar the alleged data collection.Last Thursday, U.S. congressman Edward Markey asked Apple CEO Steve Jobs to make a response within 15 business days or no later than May 12, saying "Apple needs to safeguard personal location information of its users to ensure that an iPhone doesn't become an iTrack."On Saturday, Markey called for a congressional investigation into the privacy practices of Apple and Google. In a statement, he made clear that he thinks the data collection is potentially dangerous, saying predators could have hacked into an iPhone or Android phone to find out children's location information.Apple is also reportedly being investigated in South Korea, France, Germany and Italy over the alleged tracking practice.
BEIJING, Jan. 27 (Xinhua) -- China Thursday allocated 1.039 billion yuan (157 million U.S. dollars) for areas hit by natural disasters last year.The relief funds, jointly allocated by the Ministry of Civil Affairs and the Ministry of Finance, will be used for disaster survivors to buy food, clothes, quilts and heating devices.A Ministry of Civil Affairs statement said local finance and civil affairs authorities have been ordered to publicly disclose relevant information.In 2010, several natural disasters hit China, including the 7.1-magnitude Yushu earthquake that left 2,200 people dead and the Zhouqu mudslide that left 1,700 people dead or missing.On Nov. 18, 2010, the two ministries jointly allocated 4.1 billion yuan (617 million U.S. dollars) to help natural disaster survivors pass the winter.
BEIJING, Feb. 21 (Xinhua) -- China's top leading body Monday pledged to prevent wild swings in the economy, while warning that the economic situation in 2011 would be complicated.The country should maintain stable and consistent macro-economic policies while improving accuracy, flexibility and efficiency of the policies, the Political Bureau of the Communist Party of China (CPC) Central Committee decided at a meeting presided over by President Hu Jintao, who is also General Secretary of the CPC Central Committee.Officials at the meeting were urged to "remain sober, be aware of difficulties, and work hard to fulfill the tasks this year so as to create a good beginning for the 12th Five-Year Program (2011-2015)."The top echelon of leadership reassured that China would continue an active fiscal policy and prudent monetary policy, while trying to balance steady economic growth with economic restructuring and control of inflationary expectations."It is necessary to maintain stable commodity prices, expand domestic consumption, increase investment in agriculture, speed up industrial restructuring, promote education and development of science and technology, and improve people's livelihoods and cultural services," the Political Bureau of the CPC Central Committee urged at the meeting.It also reiterated the importance of making great efforts to expand reforms in key sectors, advance the cause of opening-up, while intensifying endeavor to build a clean government and fight corruption.Members of the Political Bureau of the CPC Central Committee also discussed the drafts of the government work report and the 12th Five-year Program, or the national development plan for 2011 to 2015.The two documents will be submitted to the top legislature for discussion and approval at its forthcoming annual session in March.The period from 2011 to 2015 will be critical for China which wants to build a well-off society, said a statement from the meeting.In the next five years, in a bid to meet Chinese people's expectations for a better life, China will stick to scientific development by focusing on accelerated transformation of its way of economic growth while deepening the reform and opening-up, guaranteeing and improving people's livelihoods, according to the statement."It is necessary to solidify and boost China's success in outperforming other countries in dealing with the international financial turmoil, and advance the economy to grow at a faster and steady pace for a long time while guaranteeing social harmony and stability," the statement said.Great efforts should also be made to develop social services, advance the cause of conserving energy and resources, protecting the environment in a down-to-earth manner, as well as keep intensifying the drive to enhance reform of the government, the statement said.