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WASHINGTON, April 6 (Xinhua) -- U.S. researchers have discovered two genes in which variation affects intake of caffeine, the most widely consumed stimulant in the world, according to a report described Wednesday in the open-access journal PLoS Genetics.A team of investigators from the National Cancer Institute, Harvard School of Public Health, Brigham and Women's Hospital, and the University of North Carolina at Chapel Hill examined genetic variation across the entire genome of more than 47,000 individuals from the U.S.They found the genes -- CYP1A2, which has previously been implicated in the metabolism of caffeine, and AHR, involved in the regulation of CYP1A2, played roles in regulating intake of caffeine. Individuals with the highest-consumption genotype for either gene consumed 40 mg more caffeine than those with the lowest-consumption genotype, equivalent to the amount of one-third cup of caffeinated coffee, or one can of cola.Caffeine is implicated in numerous physiological and medical conditions; it affects sleep patterns, energy levels, mood, and mental and physical performance. The identification of genes that have an impact on daily consumption offers opportunities to better understand these conditions. Further exploration of the identified genetic variants may provide insight into the speed of caffeine metabolism, how long caffeine circulates in the blood, or how strong the physiological effects of consuming a given amount of caffeine are.
BEIJING, Feb.14 (Xinhua) - Shanghai General Motors Co. will recall 2,806 imported Cadillac CTS vehicles in China to repair faulty track bars to prevent safety risks, China's quality watchdog said on Monday.The recall, which is set to begin on March 21, includes models that were produced between June 16, 2008 and April 20, 2009, the General Administration of Quality Supervision, Inspection and Quarantine said in a statement on its website.The statement said that the company would repair or replace the rear suspension track bars of the recalled vehicles because some nuts on the bars are likely to loosen and cause worn screw threads.This could lead to a loosened track bar under extreme conditions, which is unsafe when traveling fast, it said.The company is to contact car owners to provide free checks and repairs. Owners may also contact the automaker on its free phone service (telephone number: 8008201902) for more information and to make appointments.
SAN FRANCISCO, March 7 (Xinhua) -- The world's leading hard rive producer Western Digital Corp. on Monday announced that it has agreed to buy Hitachi Ltd.'s hard disk drive unit for about 4. 3 billion U.S. dollars, a move that will create a dominant player in the industry.Western Digital said that it plans to acquire Hitachi Global Storage Technologies, a wholly-owned subsidiary of Hitachi Ltd., in cash and stock.The proposed combination will result in a customer-focused storage company with the industry's broadest product lineup backed by a rich technology portfolio, Western Digital said.According to their agreement, the resulting company will retain the Western Digital name and remain headquartered in Irvine in the U.S. state of California.The transaction has been approved by the board of directors of each company and is expected to close during the third quarter of 2011.With the purchase, Western Digital will claim 49.6 percent share of global hard disk drive unit shipments based on latest quarterly statistics, compared to 29.4 percent for Seagate Technology LLC, the industry's No. 2 supplier, research firm iSuppli pointed out.The deal will give Western Digital a lead of 20.2 percentage points over Seagate, up from a mere 2 points without the acquisition, iSuppli said in a research note released Monday.The acquisition will also allow Western Digital to enter the critical enterprise hard disk drive segment, where it currently is only a marginal player.Analysts believed that the purchase might be a consequence of declining hard disk drive shipments, which are being impacted by the rising sales of tablet computers, which don't use hard disk drives and are cutting into the sales of mobile PCs, a major market for hard drives."Amid weaker industry conditions, organic sales growth is more difficult to achieve, prompting hard disk drive suppliers to engage in acquisitions to gain market share," iSuppli noted.
BEIJING, Feb. 18 (Xinhua) -- In the next five years, China will further expand the coverage of its basic medical insurance system and ease the cost of medical services, Health Minister Chen Zhu said Friday.Chen made the remarks while addressing a meeting for the reform of the health care system.The medical expenditure that shouldered by individuals had been cut to 38.2 percent of China's annual overall spending on medical services in 2009, down from 60 percent in 2001, thanks to increasing government funding support for the measure, said Chen.He said the country is striving to bring down the ratio to below 30 percent by the end of the country's 12th five-year plan period (2011-2015).China is steadily pushing towards the implementation of a basic medicine system which aims to ensure affordable access to essential drugs for patients, Chen said.In the areas already covered by basic medicine system, the average price of basic medicine has dropped by around 30 percent, Chen added.He said that the reform of government-run hospitals, which is key to ensure that the masses gain universal access to basic health care services, must be undertaken.In 2011, more measures will be made to restructure the distribution of public hospitals, reform government-run traditional Chinese medical institutions and support building and developing hospitals in county-level regions, Chen said.
BEIJING, March 18 (Xinhuanet) --In February this year, Chinese National Geographic magazine published a series of exquisite pictures about Shicheng City (literally, Lion City), and since then, the public's strong interest in the city has been aroused again.The city of nearly 1,339 years of age, situated in east China's Zhejiang Province, has been submerged under Qiandao Lake since 1959 for the construction of the Xin'an River Hydropower Station.International archeologists vividly named the city submerged in water "time capsule." Since it is shielded from the erosion by wind, rain and sun, a city submerged in water comparatively maintains a stable condition, thus making the city a virtual time vessel. Seen from the pictures of Shicheng City, stairs in ancient houses, walls and memorial arches remain the same as they were thousands of years ago.Shicheng City was named after the Wu Shi Mountain (literally, Five Lion Mountain) in the northern part of Sui'an County, Zhejiang. It was once the center of politics, economics and culture of Sui'an County in that area.As written in the "History of Sui'an County," there are all together 265 arches submerged under Qiandao Lake, among which the Jie Xiao Memorial Arch's fine carvings remain well-preserved.According to the restored map of Shicheng, there were five city gates in all directions. You can find one city gate tower on each city gate and all together there are five towers. Besides, six streets in Shicheng City were used to connect every corner of the city as a whole. The typical roads in Shicheng City were stone roads, tidily paved by flagstone and pebbles.