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SHENZHEN, June 4 (Xinhua) -- Chinese scientists who have fully sequenced the genome of the new E. Coli spreading through Europe said Saturday they found genes in the bacteria that gave it resistance to eight classes of antibiotics.Researchers with the Beijing Genomics Institute, the world's largest DNA sequencing center, have found genes in the newly identified 0104 strain of E. Coli bacteria that made it resistant to major classes of antibiotics including sulfonamide, cephalothin, penicillin and streptomycin.This helped explain why doctors in Europe had difficulties in fighting the bug that has killed 18 people and sickened nearly 2,000, BGI's major research arm in Shenzhen said on its website Saturday.This would help doctors choose right medicines for the treatment, it said.The researchers are developing a diagnostic kit which will be used to detect the bacteria and prevent the epidemic from spreading further.The Chinese researchers obtained DNA samples of the bacteria from collaborating scientists in Germany and fully sequenced its genome in three days this week.They announced on Thursday the E. Coli spreading through Europe was "a new strain of bacteria that is highly infectious and toxic".The 0104 strain of E. Coli was not previously involved in any E. Coli outbreaks. However, it has 93 percent sequence similarity with the EAEC 55989 E. Coli strain which was isolated in the Central African Republic and known to cause seriously diarrhea, BGI said.The source of the outbreak is unknown, but scientists say it is highly likely to have originated in contaminated vegetables or salad in Germany.

SAN FRANCISCO, June 23 (Xinhua) -- Facebook announced Thursday that Netflix CEO and Chairman Reed Hastings has joined the social network company's board of directors.Hastings, who successfully managed Netflix through an IPO in 2002, is expected to provide useful guidance for Facebook which plans to go public.As the most popular subscription-based movie and television show rental service in the United States, Netflix could also help Facebook figure out how to enter the business of music streaming and movies, which, CEO Mark Zuckerberg said at the eG8 Forum held in Paris last month, would be Facebook's next focus.The Facebook board seat could also help Netflix to catch up with the social evolution of the Internet with its 23.6 million subscribers in the U.S. and Canada."Reed is an entrepreneur and technologist who has led Netflix to transform the way people watch movies and TV," said Zuckerberg in a statement. "He has built a culture of continuous rapid innovation, something we share and work hard to build every day.""Facebook is propelling a fundamental change in how people connect with each other and share all kinds of content," said Hastings. "I'm looking forward to working with Mark and the rest of the board to help Facebook take advantage of all the opportunities ahead."

WASHINGTON, June 14 (Xinhua) -- Short sleep duration may contribute to the development or worsening of hyperactivity and inattention during early childhood, suggests a research abstract that was presented Tuesday at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC.Results show that less sleep in preschool-age children significantly predicted worse parent-reported hyperactivity and inattention at kindergarten. The sample consisted of approximately 6,860 children, and analyses controlled for gender, ethnicity and family income."Children who were reported to sleep less in preschool were rated by their parents as more hyperactive and less attentive compared to their peers at kindergarten," said lead author Erika Gaylor, senior researcher for SRI International, an independent, nonprofit research institute in Menlo Park, California. "These findings suggest that some children who are not getting adequate sleep may be at risk for developing behavioral problems manifested by hyperactivity, impulsivity, and problems sitting still and paying attention." According to the authors, attention-deficit/hyperactivity disorder (ADHD) is not generally diagnosed until the school-age years. However, the onset of developmentally inappropriate inattention, hyperactivity and impulsivity is often much younger. Sleep problems, particularly difficulty falling asleep and staying asleep, are frequently reported in children and adolescents with ADHD. However, the direction of causation, if any, has been difficult to determine. Longitudinal studies may provide a window into the direction of this complex relationship.Last year at SLEEP 2010, Gaylor reported that having a regular bedtime was the most consistent predictor of positive developmental outcomes at four years of age. Having an earlier bedtime also was predictive of higher scores for most developmental measures.

WASHINGTON, Sept. 12 (Xinhua) -- An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and alcohol abuse in people, U.S. researchers find.Over the course of four weeks, mice genetically engineered to lack the gene for protein kinase C (PKC) epsilon consumed less of a nicotine-containing water solution than normal mice, and were less likely to return to a chamber in which they had been given nicotine. In contrast, normal mice steadily increased their consumption of nicotine solution while the mice lacking PKC epsilon did not.The study conducted by researchers at the Ernest Gallo Clinic and Research Center, affiliated with the University of California, San Francisco, appeared Monday in the online edition of the Proceedings of the National Academy of Sciences.In normal mice, as in humans, nicotine binds to a certain class of nicotinic receptors located on dopamine neurons, which causes dopamine to be released in the brain. Dopamine creates a feeling of enjoyment, and thus prompts a sense of reward. Researchers found that mice lacking PKC epsilon are deficient in these nicotinic receptors.The finding complements earlier research in which researchers found that mice genetically engineered to lack the PKC epsilon enzyme drank less alcohol than normal mice and were disinclined to return to a chamber in which they had been given alcohol."This could mean that these mice might not get the same sense of reward from nicotine or alcohol," said Gallo senior associate director and investigator Robert Messing. "The enzyme looks like it regulates the part of the reward system that involves these nicotinic receptors."The reward system is a complex of areas in the brain that affect craving for nicotine, alcohol and other addictive substances.The next step in the research, said Messing, would be to develop compounds that inhibit PKC epsilon. The ultimate goal, he added, would be medications that could be used "to take the edge off of addiction by helping people get over some of their reward craving."

LOS ANGELES, June 14 (Xinhua) -- Rural elders are far more likely to be overweight or obese, physically inactive and food insecure than their suburban counterparts, three risk factors for heart disease, diabetes and repeated falls, a new study suggests."The countryside can have an isolating effect," said lead researcher Steven P. Wallace, deputy director of the Center for Health Policy Research at the University of California, Los Angeles. "When even a trip to the grocery store is a significant drive, seniors can become trapped in their houses."The researchers based their finding on analyzing the lifestyles and living conditions in California countryside.The study found that despite living in the countryside, where open space is plentiful and there is often significant agricultural production, California's more than half a million rural elders have higher rates of developing various health problems than their urban and suburban counterparts.These problems include:-- Older adults in rural areas are more often overweight or obese (61.3 percent) than their urban (57.3 percent) and suburban (54.0 percent) counterparts;-- Rural older adults do not get enough exercise;-- One in five rural elders do not participate in either moderate or vigorous physical activity in their leisure time;-- Rural and urban older adults are more likely to be food insecure; and-- One in five low-income older adults in rural settings report that they cannot consistently afford enough food to last the month, a rate is about twice that of low-income suburban adults.Approximately 710,000 Californians aged 65 and over live in the countryside -- almost one-fifth of all older adults in the state. Yet rural elders experience unique challenges to healthy living, including a lack of sidewalks, street lights, transportation services, access to healthy food outlets, parks, exercise facilities and health care sites. California's rural areas are also challenged by a dearth of physicians and other primary care providers, compelling many seniors to travel long distances to seek care, according to the study.The findings were published Tuesday on the website of the American Association for the Advancement of Science.