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NEW YORK (AP) -- The Dow Jones Industrial Average climbed above 27,000 for the first time ever Thursday. The S&P 500 also hit a closing high milestone of its own Thursday, a day after its first move above 3,000.Steep losses in drugmakers and real estate companies were offset by gains for banks and technology companies.Nvidia climbed 3.9% and Goldman Sachs rose 2.6%.Pharmaceutical makers dropped after the White House scrapped a plan to overhaul a system of rebates those companies pay to insurers and distributors.Bond yields spiked following weak demand at an auction for 30-year Treasurys.The S&P 500 rose 6 points, or 0.2%, to 2,999.The Dow rose 227 points, or 0.8%, to 27,088. The Nasdaq fell 6 points, or 0.1%, to 8,196. 744

New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967

NEW ORLEANS, La. – The oldest known U.S. veteran of World War II celebrated his 111th birthday over the weekend and he did it in style.Like it has for the past five years, The National WWII Museum hosted a birthday celebration for Lawrence Brooks on Saturday. This year though, they followed social distancing guidelines and the centenarian enjoyed the festivities from his home in New Orleans.From his porch, Brooks watched as military planes from the Aeroshell Aerobatic Team and The Big Easy Wing flew over just for him.The museum also had its vocal trio, The Victory Belles, perform a series of numbers for Brooks, including “Happy Birthday.”Lastly, Brooks was presented with a cake, a recorded message from the museum’s CEO, and nearly 10,000 birthday cards collected as a result of a national card drive.“It is such an honor to have the oldest living U.S. veteran of World War II living so close to our institution, and it was meaningful for us to continue to celebrate Lawrence Brooks and his incredible life in a safe manner this year,” said the museum’s assistant director of public engagement, Amber Mitchell, in a press release. “As we continue to lose members of The Greatest Generation, it is so important that we honor these men and women for their bravery and sacrifice while they are with us.”Brooks served in the predominantly African American 91st Engineer Battalion, which was stationed in New Guinea and then the Philippines during WWII, according to the museum. He was married to the late Leona B. Brooks and is the father of five children and five stepchildren. Brooks' oral history has been recorded by the museum and is available here. 1667

New heart health research found that taking a low-dose daily aspirin to cut chances of a heart attack or stroke may have risks that outweigh the benefits.The latest studies revealed the effects of the blood-thinning, anti-inflammatory drug on patients, who did not yet develop heart disease or other heart-related issues but were at moderate risk.Research found aspirin does help patients with diabetes, who are at higher risk to develop or die from heart problems. However, the risk of serious bleeding far outweighed the benefit of taking the drug.The study found aspirin was not effective in preventing heart attacks or strokes for moderate risk patients, because they had other health issues, including high blood pressure, high cholesterol and smoking.Doctors also cautioned using fish oil supplements, instead of aspirin, would have similar disappointing results. Instead, health professionals suggest eating fish to improve your heart’s health.Fish oil may be more beneficial for people who have already suffered a heart attack. 1043

NORFOLK, Neb. -- Something as simple as going for a walk with family, Troy Bowers doesn’t take for granted, considering he hasn’t been able to do it for years.Bowers broke his ankle multiple times and went through a series of surgeries that caused endless pain.“I was to the point where I was potentially going to lose the lower part of my leg and my foot just because it hurt so bad,” Bowers said.But then a local doctor gave him hope. Dr. Demetrio Aguila III is the founder, CEO and president of Healing Hands of Nebraska.Healing Hands of Nebraska is a medical and surgical practice that focuses primarily on the surgical management of chronic pain. Dr. Aguila says a program called the M25 Program is the heart and soul of their practice – inspired by his time serving as a combat flight surgeon in Afghanistan.“The M25 program is a mechanism by which patients and doctors and communities work together to invest in each other to get the care that they need without causing a financial burden,” Dr. Aguila said.If somebody can’t afford a surgery, the M25 Program gives them the opportunity to pay for their procedure through community service hours. Healing Hands of Nebraska collaborates with multiple organizations where patients can volunteer.“You volunteer your time, and then they call me up, ‘she’s finished all the hours you asked for. Ok, send her over’. We’ll do her surgery… no charge… zero charge.”The M25 Program is what saved the Bowers' family from going into debilitating medical debt.“We were basically bankrupt, and luckily, when we needed it the most, I guess God was looking out for us and Dr. Aguila was willing to help,” Bowers said.Bowers chose the Orphan Grain Train for his community service – a Christian volunteer network that ships donated food, clothing, and medical items to people in need throughout the U.S. and world.“Through I believe like 450 community hours, I was able to have three procedures by Dr. Aguila to finish up my nerve repair. And I don’t even know what that would have cost… thousands, I mean a lot,” Bowers said.But due to his pain, he wasn’t able to do too many hours. So, he asked his church, Grace Lutheran, for help.“We had a group of kids of about 6-12 every week pitching in for about an hour a week, and those service hours really added up,” Grace Lutheran Pastor Chris Asbury said.Every Wednesday, Pastor Asbury and a group of middle schoolers – called Happy Helpers – donated their time to help Bowers.“Them young people helped me walk, and I got to save my leg because of them and other volunteers," Bowers said. "They made that difference.”Every time they volunteered, they prayed that they could be a blessing to the Bowers' family.“As Christ loved us, we love the people around us," Pastor Asbury said. "And we don’t just talk about it, but we find everyday ways to do that. It doesn’t have to be big. Most of the time it’s never newsworthy, but this certainly is.”You may be wondering, how is this all even possible? Well, it’s more simple than you think.“We offer significantly discounted fees for our services here compared to what you would find at other practices because we don’t involve the insurance companies,” Dr. Aguila said.According to Dr. Aguila, patients know exactly what they’re getting into financially when they enter the office. Without insurance involved, there’s no administrative costs for the patient. Dr. Aguila says they can pay everything up front, split up payments over time, or go through the M25 Program.“Last year, two thirds of all individual bankruptcies in the United States were tied to medical debt,” Dr. Aguila said.And of those two thirds of people, Dr. Aguila says three fourths had medical insurance.“We’re gonna work outside the system in order to build a better system that’s fair to patients, that’s transparent,” Dr. Aguila said.When people use the M25 program, Dr. Aguila doesn’t get paid for his professional fees. However, the office says they don’t look at it as a financial hit. Rather, they look at it as a way to give back to the community, calling it medical mission work in their own backyard.“Who loses? Nobody. Who wins? Everyone,” Dr. Aguila said.Now, Bowers can go on with his life, spending time with his family.“Riding horses with my daughter, fishing with my son, we’re doing great.”Dr. Aguila says doctors have reached out from all over the world trying to figure out how they can implement their own program. He says he’d like to see M25 change the conversation about healthcare, restore the doctor-patient relationship, and spur a resurgence of volunteerism in the U.S.“It is my fervent hope, that we will rekindle, reignite in the soul of the American people a desire to volunteer and help their neighbors,” Dr. Aguila said. 4762