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Strong opioid dosage is the topic of a two-day public hearing by the Food and Drug Administration — which is trying to discern the benefits and risks.For Katrina King, her opioid addiction began with a back injury. It got so bad she spent two years behind bars after getting caught with forged prescriptions. King blames being put on high-dose medication too strong for her injury."The extended release — introducing that into the picture as such a potent dose so early in my diagnosis without trying anything else — ended up being catastrophic," she said.Some people have suggested the FDA remove high-dose opioids form the market to fight the deadly epidemic. Others argue the stronger meds are necessary to manage pain for some patients and getting rid of it could worsen pain for those people, leading to potential suicides."We don't want to cause additional suffering for people who have unmanageable pain that does make them feel they don't want to live anymore. On the other side of that, I would challenge the pharmaceutical industry and the FDA to come up with other methods of pain control," King said.The FDA will review public comments and decide whether to make change, which could include tougher regulations on reducing the use of high-dose opioids. 1276
Six people have died as a result of a severe storm system that caused blizzard conditions in the US Midwest and torrential rain and flood threats in the South.The system dumped about a foot of snow in the Dakotas, Nebraska and Minnesota by Friday morning. It was forecast to bring heavy rain farther east Friday and cause messy travel conditions.More than 11 inches of rain fell across some areas of Louisiana and Mississippi, where flash flood emergencies were issued overnight into Friday morning. More than 50 million people remained under flood and flash flood watches from Louisiana to New Jersey.The snow across the northern Plains and upper Midwest was expected to wind down throughout Friday morning, but blowing snow was limiting visibility. 762

Prince Andrew said in a statement Wednesday that he would step back from public duties "for the foreseeable future" following a firestorm of criticism over his association with convicted sex offender Jeffrey Epstein.Here's the full statement from the Duke of York:"It has become clear to me over the last few days that the circumstances relating to my former association with Jeffrey Epstein has become a major disruption to my family's work and the valuable work going on in the many organizations and charities that I am proud to support."Therefore, I have asked Her Majesty if I may step back from public duties for the foreseeable future, and she has given her permission."I continue to unequivocally regret my ill-judged association with Jeffrey Epstein. His suicide has left many unanswered questions, particularly for his victims, and I deeply sympathize with everyone who has been affected and wants some form of closure. I can only hope that, in time, they will be able to rebuild their lives. Of course, I am willing to help any appropriate law enforcement agency with their investigations, if required." 1126
SAN BERNADINO, Cali. -- Matthew Valdivia woke to the smell of smoke, and looked outside to see the glow of a wildfire in the hills near his home in San Bernardino early Thursday.After waking up his wife and children and some neighbors, the Valdivia family joined thousands of other Southern Californians who've had to flee fires sweeping the state. And like those other evacuees, the Valdivias hoped firefighters could save their house.It burned to the ground before sunrise.Valdivia's home was one of at least six that the Hillside Fire, which started in the hills above San Bernardino after midnight, damaged or destroyed Thursday as winds pushed it down into the city, officials say.It is one of 711
Sault Ste. Marie, Mich. — The wordsmiths at Lake Superior State University in Michigan have released LSSU's 44th annual "List of Words Banished from the Queen's English for Mis-use, Over-use and General Uselessness." LSSU's word banishment tradition is now in its fifth decade, and was started by the late W. T. Rabe, a public relations director at Lake Superior State University.Through the years, LSSU has received tens of thousands of nominations for the list, which now includes more than 1,000 entries. This year's list is comprised of nominations that come from the 589
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