郑州怀孕几个月做四维检查比较好(郑州四维彩超多长时间查) (今日更新中)

SAN DIEGO (KGTV) - Teachers across the U.S. are working to diversify the books in their classroom libraries, according to Harvard University and Collaborative Classrooms."It’s been more than 50 years since literacy experts first stressed the need for more diverse books in the classroom, and yet reading lists look surprisingly the same as they did in 1970," an excerpt from Harvard Ed Magazine reads.Mother Tancy Campbell wasn't exposed to characters who were African American growing up."It wasn't until high school that I started seeing books that had people that looked like me and started getting into black authors like Toni Morrison and Maya Angelou," Campbell says.Third-grade Teacher Kyle Luciani noticed the disparity last year when he started looking through his own classroom library. He went to work last year adding to his library. "I noticed almost all characters are animals or white," Luciani said. "I have books about biographies, about Jackie Chan, about Oprah Winfrey. Books on civil rights leaders ... Books such as don’t touch my hair, books on awareness of cultures."He said after George Floyd died, he added 0 worth of books on diversity and culture to his classroom.Last year, Luciani said he saw the electric change in his students."They love them! I mean I don’t think they’re always aware, 'Oh, it's someone of color,' but it's cool seeing them drawn to them automatically," Luciani said.In a 2015 Collaborative Classroom Diversity Review Book Project, 59% of books in more than 200,000 classrooms across the country had white characters and about 90% of authors were white. A team member of the project said this makes children of other ethnicities feel invisible or insignificant.Licensed psychologist Dr. Michelle Carcel is Latina and trained to teach diversity and inclusion courses. "I certainly take this to heart. It is so important to identify with others who are like you and you can see similarities and so you can also see diversity as a welcoming thing," said Carcel.Campbell believes diverse books will shape the future."I think it gives them confidence that they're the center of the story, I think that it shows them a hero can look like them," said Campbell. "I think it gives them stories of their background, that they might not have known before of their history and their culture that they didn't learn from their parents or grandparents."She has a diverse home library for her 9- and 5-year-old children. She said the latest book they read is about a girl in Africa who has to walk a long way to find water, bring it home, and boil it before she can take a sip. She said her daughter was touched by the book and filled with gratitude we have access to clean drinking water.Carcel said diverse books like this can break down systemic racism and heal generational trauma. 2829

SAN DIEGO (KGTV) — The National Institutes of Health highlighted research Tuesday out of UC San Diego that could unlock a new way to treat COVID-19.The research reveals new insight into how the coronavirus hijacks cells, and how doctors might be able to set traps or decoys to combat the virus. The findings were published in the journal Cell last month.“It does open up another avenue for a potential treatment,” said UC San Diego distinguished professor Dr. Jeffrey Esko. “It’s not a cure. It would be something that would tamp down infection potentially.”Since January, scientists around the world have understood that SARS-Co-V2, the official name of the new coronavirus, enters cells by latching onto a specific receptor on the cell’s surface, called ACE2.The UCSD team, led by Dr. Esko and visiting scholar Dr. Thomas Clausen, discovered that this entry mechanism is actually a two-step process, and the virus must also attach to a long chain of sugars called heparan sulfate.“We’ve shown this is fundamental to the infectious mechanism, so it needs to be part of every study from now on,” said Clausen.All cells are coated with a complex layer of sugars, or carbohydrates, called glycans. Heparan sulfate is one type of glycan that is known to play a key role in the infection process in several viruses, including herpes and other coronaviruses.It’s a complicated process to picture so the researchers offer an analogy: imagine a bird, soaring over trees, hunting a worm on the forest floor. The bird is the coronavirus and the trees are the thick layer of glycans that coat the surface of the cell.To reach the worm, which in this case is the receptor ACE2, the bird must navigate its way through the trees, specifically through heparan sulfate.The UCSD found that by removing the heparan sulfate trees with an enzyme, they were able to prevent the virus from infecting cells. In laboratory testing, they also found a second technique worked to foil the virus: introducing more trees as bait.The team found that heparin, an FDA-approved drug that is similar in structure to heparan sulfate, successfully acted as decoy. Heparin is a widely used drug designed to treat blood clots. Since blood clots and strokes are common complications with COVID-19, many doctors already administer heparin to patients.The UCSD team demonstrated that the two approaches can block infection in lab-grown cells about 80 to 90 percent of the time.“Certainly in the laboratory you can demonstrate that it works, but to deploy it and use it as a therapeutic has not been demonstrated,” Esko said.The NIH noted that more studies are planned to explore whether heparin, heparan sulfate, or drugs that target heparan sulfate might yield a viable COVID-19 treatment.Dr. Esko said he’s already been in talks with companies that plan to use their study as a rationale for a clinical trial.“It is very humbling when you realize we’re working on a pandemic right now, and maybe what we’ve done can contribute to a treatment for the disease,” he said. 3038

SAN DIEGO (KGTV) - Teachers are quickly adapting to online lesson plans to engage their students.Third grade teacher Carlisa Flanders said Friday was the first day she'd been back to school since Grant K-8 shut its doors March 13 due to coronavirus concerns.Flanders said the day the school closed was hectic and stressful, "we had a couple hours to hussle. I put together two weeks of work, took as much as I could went home and hunkered down."She was emotional thinking of the future, wondering when she was going to see her students again and when school would reopen.Tuesday was the day she was able to go online, using a program called Zoom, and video conference with her students. She said 18 of the 21 students have been attending school this week.Friday morning, their homework assignment was to bring one thing to share. Many of her students showed off their pets."The majority of my focus is going to be making sure I stay connected with my students, making sure they feel the love," she said, gesturing at a board behind her with the words, 'Good Morning! You are awesome! You are loved!' written in different colored markers.Flanders said right now class is optional and labeled as enrichment. She said Thursday she read a book to the kids.Parents, like mom Leona Smith, said the social interaction from class is exactly what her son has been missing, "that connection he has, and the bonds that he has with his friends and his teacher it's like no other.""I think we forget how much school and their friends and their teachers are part of their everyday life," Smith said.Mrs. Flanders has been working tirelessly to bridge boundaries with online education, "I am now texting, communicating with friends I now have in Georgia, in Texas, in Oregon who are also third grade teachers and I'm collaborating virtually with strangers but their hearts are in the exact same place as mine and we're all just like try this, try this, try this."She said her tech savvy students are also stepping up teaching her tricks, like starting a chat and sharing pictures through the program. 'Our first lesson was how to mute and unmute the microphone,' Mrs. Flanders said.Friday was emotional. Mrs. Flanders said she was glad to go back to school and see fellow teachers' cars in the parking lot, but could only wave hello from a distance. "I got to go back to school for 20 minutes, I got my charts, I got our class mascot, this is happy," she said holding a rainbow hedgehog stuffed animal. She said she also grabbed a large stack of books.She was also happy to get back a semblance of a routine, saying class will start online officially on April 27."Oh gosh, it's mind boggling to think how these grades will actually count towards them finishing the third grade year," Mrs. Flanders said concerned.She's focusing instead on each lesson and the positive impact she can make on her students."At the end of every school day I usually hug, high-five or fist bump my kids, so our first Zoom, we decided this is our new way of hugging," She said making an 'air-hug' gesture, "So to all of you here's a hug. We'll get through this."The San Diego Unified School District said schools will be soft launching online education April 6. That way they can connect students in need with computers and WiFi, so everyone is ready for the hard launch April 27. That means teachers will assign tasks that will be graded.The district said if a student cannot connect online, they will not be penalized and their grade will be frozen. 3523

SAN DIEGO (KGTV) — The Department of Defense has awarded a San Diego biotech company up to million to help develop a next-generation drug to fight COVID-19.Sorrento Therapeutics calls the drug a “rapid countermeasure” against the disease, one that might serve as a vaccine substitute in certain populations or a critical stopgap tool if the virus mutates.“With this, we have a new platform potentially that can respond very quickly to any type of emerging threat,” said CEO Dr. Henry Ji.Sorrento is trying to become the first company to develop an approved DNA-encoded monoclonal antibody treatment. The approach is similar to the experimental monoclonal antibody treatment used on President Trump, but Sorrento’s concept is a more advanced version that offers several benefits.Sorrento’s drug is designed to be used as either a treatment in infected patients or a fast-forming layer of defense in healthy people. The company said its solution should be cheaper and easier to deploy than existing monoclonal antibodies, while offering vaccine-like protective effects that last for several months rather than just two or three weeks.Antibodies are one of the body’s key defense mechanisms. They seek out pathogens and bind to them, marking the invader for destruction like ground troops marking an enemy base for an airstrike. In some cases, antibodies can even neutralize an invader themselves by blocking its method of entry into cells.Monoclonal antibodies are antibodies designed by scientists to neutralize a pathogen. They are hand-picked, genetically modified super antibodies that are cloned in labs.However, the process of growing these super soldiers in the lab is difficult, transporting them requires a cold chain, and as a result, monoclonal antibodies are among the most expensive drugs in the world.Instead of giving people an infusion of pre-made antibodies, Sorrento’s idea is to give people a shot of DNA that instructs some of their cells to churn out perfectly pre-designed antibodies.“It's much easier to make enough DNA to treat a large number of people than it is to make enough protein to treat a large number of people. That’s just a fact about manufacturing,” said Dr. Robert Allen, Sorrento’s chief scientific officer on the project.Dr. Allen said the company is hopeful the drug will induce cells to make protective antibodies for six months or more.This DNA approach to an antibody treatment has never been approved for any disease but other companies are working on their own versions of it. Another biotech with ties to San Diego, Inovio Pharmaceuticals, became the first company to test this approach in humans in 2019 for a drug targeting the Zika virus.Sorrento’s approach is similar to the way DNA vaccines work, but it cuts out intermediary steps and jumpstarts the production of antibodies, rather than leaving the production of antibodies up to the body’s immune system. The result is that protective antibodies can start circulating in days after injection rather than weeks, the company said.“What this is capable of doing is it bypasses the need for the immune system,” said Dr. Mark Brunswick, Sorrento’s senior vice president for regulatory affairs.The drug is unlikely to replace a vaccine in most situations because vaccines can produce other defense mechanisms like T-cells that work in conjunction with antibodies. But the drug might work better than a vaccine for the elderly and others with weakened immune systems who are unable to produce a robust number of antibodies on their own, Brunswick said.Still, the company still has a lot of pre-clinical work and testing to go. Sorrento is hoping to have the drug ready for human trials in four to six months.By then, vaccines from Pfizer and Moderna will likely be widely available, but Dr. Ji said the world needs to prepare for the possibility this virus will mutate.“When you vaccinate hundreds of millions, potentially billions of people, the virus is under tremendous evolution pressure,” he said. “It will escape. It’s guaranteed that the virus is going to mutate and escape all of the vaccines we’re trying to create.”If it does, he said Sorrento will be ready to rapidly deploy its DNA-based countermeasure. 4223

SAN DIEGO (KGTV) - The Class of 2019 is graduating to a significantly tougher rental market than graduates from ten years ago. Rent hikes and slow income growth are making it more difficult for new grads to afford rental homes, according to a HotPads report. A typical college graduate in the U.S. spends 45.3 percent of his or her income on the median rent of ,740, up from 40.5 percent for the Class of 2009. The rent burden has grown by 22 percent as early-career median incomes have dropped 14.5 percent, HotPads analysts say. In San Diego, the median rent is more than the entire income for new graduates with degrees including biology and business management, at ,000 per year, and nearly the entire income for those with degrees in psychology, at roughly ,000 per year, HotPads reports. The top-earning degrees nationwide were primarily in engineering fields, with mining and mineral engineers earning a median ,854 after college. “As rent prices and student debts rise, affordability concerns for recent college graduates have garnered attention on the national stage,” said Joshua Clark, economist at HotPads. “Graduating from college still typically pays off in the long run, but slower wage growth for college graduates and rising costs have dampened the immediate financial benefits associated with a four-year degree. As renters consider their career interests and their short-term costs of living, where and how they live post-graduation can have more of an impact on their finances now than ever before." Although an education is a major financial investment, it pays off in San Diego’s tight rental market. Renters without a four-year degree would spend 129.7 percent of the median income on rent. Want to know how much you can afford? See the rent ratio chart here. 1801

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