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SAN DIEGO (KGTV) — Independent reviews by the FDA show the COVID-19 vaccines by Pfizer and Moderna have similar levels of safety and efficacy, although there are early indications of potential differences.Both vaccines rely on the same basic approach: jumpstarting the immune system with messenger RNA. The FDA confirmed their overall efficacy is essentially identical; 95 percent for Pfizer and 94.1 percent for Moderna.However, signals in the data suggest Moderna’s vaccine may better protect against severe cases of COVID-19, while Pfizer’s vaccine may work better in adults over 65. But experts warned those differences may just be statistical illusions.In Moderna’s study of 30,000 volunteers, 30 people got severe cases of COVID-19. All 30 of those cases were in the placebo group, suggesting the vaccine offers powerful protection against the most serious symptoms.In Pfizer’s trial of 44,000 volunteers, one vaccinated person got a severe case compared to 10 people in the placebo group.“We still need more data,” said Dr. Abisola Olulade of Sharp Rees-Stealy. “It's not a reason to recommend one versus the other.”In adults over 65, the efficacy of Moderna’s vaccine dipped slightly to 86.4 percent. Pfizer’s vaccine was 92.9 percent effective in people aged 65 to 74 and 100 percent effective in individuals 75 and up.“When I think people in the community look at that number, they might say, ‘Oh, that Moderna vaccine probably isn't as good for the older population compared to the Pfizer vaccine.’ But as a clinician looking at numbers, they're both amazing,” said UC San Francisco infectious disease expert Dr. Peter Chin-Hong.FDA scientists found both vaccines are safe but short-term side effects are common, especially with Moderna’s drug. Both vaccines are administered in two doses. The table below lists the percentage of vaccinated volunteers who reported a side effect after either dose, although side effects were most common after the second injection.Side effect Moderna PfizerFatigue 68.5% 62.9%Headache 63.0% 55.1%Muscle pain59.6%38.3%Joint pain44.8%23.6%Chills43.4%31.9%Fever14.8%14.2%Typically the symptoms went away in one day.“Just because a vaccine has side effects doesn’t mean it’s not safe,” said Dr. Olulade. “We know that side effects happen actually because your immune system is working and waking up. It's actually a positive thing.”The slight difference in side effects could be because of differences in the way researchers polled volunteers, or it could be something with the architecture of the vaccines, experts said.The companies use different tiny bubbles of fat to enclose the messenger RNA. Moderna’s bubble is a little stronger and more stable so it doesn’t need to be stored at sub-arctic temperatures.“It could be that [Moderna’s] elicits a little more inflammation than the other,” Dr. Chin-Hong said.Having slightly more side effects could be a sign that Moderna’s vaccine prompts a stronger immune response that might lead to longer-lasting immunity, but the durability of either vaccine remains one of the most pressing unanswered questions.The biggest difference may be where the vaccines are deployed. Since Pfizer's vaccine needs to be stored at such cold temperatures, experts said Moderna's vaccine may be prioritized for rural hospitals and community health centers that lack ultra-cold storage units. 3370

SAN DIEGO (KGTV) - If you run a small business, there’s a good chance you can find affordable office space. But what you may not find is flexibility, and you could get stuck with a long-term lease. Or, you could consider one of the many co-working spaces around San Diego. 10News is taking a closer look at that option in our quest to help you Make it in San Diego. "This is a tiny, skinny office that can seat two people but that's all we need," says Kyle Carpenter looking around his 15-feet by 6-feet office.Carpenter is CEO of SolidSurface.com"So yeah, we just launched this," adds Carpenter showing off his new website design. RELATED: Tips to help you work from homeSolidSurface.com is an online market place for decorative kitchen and bathroom surface material sold directly to consumers. Carpenter founded his small business in 2007 and used to run it out of his home. But, one thing was missing. "I needed a space to work, but it was also very important to be around other people," says Carpenter.He found that social interaction and affordable shared office space at Cross Campus near downtown San Diego. "That's why we exist, to bring people together. So, people can be productive in this space and also help each other out," says Briana Tovey, Senior Campus Manager at Cross Campus in San Diego. Cross Campus also has locations in Los Angeles and Scottsdale and each office has the space to host larger events. The shared office space here in San Diego is over 20-thousand square feet housing about 250 members."First of all, we're in Little Italy, which is very cool," adds Tovey with a smile. Going to work within walking distance to the city’s trendiest restaurants, cafes, and bars is an excellent start. An entrepreneur, a writer, any small business for that matter can use a desk for as little as 0 a month. From there, think a la carte for office space. And as your company grows, Cross Campus has the space to help you do so. In addition, for small businesses just trying to navigate through growing pains, there is no long-term commitment. "One of the benefits of our space is that we’re super flexible,” says Tovey. “So, you don't have to commit to a 3-year lease or even a 1-year lease.” You also avoid the cost of a complete build out. Your desk, internet, printing, coffee, snacks, kitchen, they're all provided. Plus, the occasional community happy hour. You can't get that at home. "To be able to be around this sort of creative, vibrant community," says Carpenter "It’s kind of inspiring."Cross Campus will give you a tour of their San Diego location if you're in the market for shared office space. There are also numerous co-working spaces throughout San Diego County. Below are just a few that might fit your needs: CommonGrounds is located in Carlsbad conveniently across from the Poinsettia Coaster Station. This site captures the California work-life with expansive outdoor seating and patio area centered around INVITA café. Their on-site chef cooks daily organic specials that pair beautifully with the cafe's Italian espresso beverages. CommonGrounds features private offices, traditional co-working, and meeting spaces housing over 200 members representing over 100 companies.WeWork has locations in La Jolla UTC and Downtown.Premier Workspaces has locations in Downtown, La Jolla, Del Mar, Mission Valley, and Rancho Bernardo.Regus offers both Commercial Office Space and Co-working space. 3443

SAN DIEGO (KGTV) - It's a great weekend to get out and enjoy San Diego's springtime with music, brews, and some heavy machinery.Del Mar's Goodguys 18th Meguiar's Del Mar Nationals roars into town, giving car heads the ultimate opportunity to see hot rods, muscle cars, and more.On the music scene, Snoop Dogg and Warren G will kick off the weekend with a show at The Observatory, and American Mariachi will debut at the Old Globe Theatre.RELATED: Springtime festivals in San DiegoFor locals looking for a festival, you can't go wrong with Julian's Gold Rush Days or the San Marcos Spring Festival and Street Fair.Here's a look at some of the things happening around San Diego this weekend:THURSDAY 710

SAN DIEGO (KGTV) -- Less than a day after announcing that two students have contracted coronavirus, San Diego State University officials confirmed Thursday that two more students tested positive for the disease.Thursday's announcement raises the number of coronavirus cases on SDSU's campus to four since kicking off the fall semester this week.Officials said the two new cases are unrelated to the previous cases, and that the two students had only been to the campus to see testing at the Student Health Services. The two unidentified students are "recovering well and are away from campus," according to officials.RELATED: SDSU begins 2020-21 school year with mostly virtual classes"The two students did not interact with any SDSU employees or spaces, outside of the Student Health Services Outdoor COVID-19 Test Collection Booth, and were not in any other spaces utilized by the campus community," said Libby Skiles, Ed.D., SDSU Student Health Services Director.On Wednesday, the university confirmed two students had tested positive and that both students live off-campus. The students were also tested by the college's Student Health Services.Wednesday's cases are not believed to be connected to any reported off-campus gatherings, the school statement said.The school said the risk to others on campus is low and SHS is in the process of performing contact tracing.San Diego State: Two students test positive for COVID-19; Risk to campus 'low'Campus officials previously reported it has had 27 confirmed COVID-19 cases within the broader campus community among faculty, staff, students, and visitors to campus, including the SDSU Imperial Valley campus.SDSU started its 2020-21 school year this week with nearly all virtual classes, however, the campus isn't completely closed to students. There are about 2,600 students living on campus this semester, and hundreds more who have to visit the campus for certain matters. Normally, SDSU would have about 7,500 students living on campus.In a warning to the student body and staff, Skiles urged the SDSU community to continue using prevention techniques, "including wearing facial coverings and following U.S. Centers for Disease Control and Protection guidance to protect yourself and those around you.""Washing your hands for at least 20 seconds, and frequently, is one of the most important ways to help prevent the spread of COVID-19," said Skiles. 2417

SAN DIEGO (KGTV) - Local health care workers are seeing a massive number of at-risk patients through virtual visits amid concerns over COVID-19. “We've gone from having 100 visits a day [by phone or video] to 1,200 visits just yesterday alone, says Dr. Abi Olulade with San Diego's Sharp Rees-Stealy Group. She and hundreds of doctors with Sharp Healthcare are putting a special emphasis on telehealth appointments with patients who are considered at-risk because their immune systems can be weaker. RELATED: Coronavirus Impact: Concern over nurses' protective gear“[Patients] with lung disease, heart disease, diabetes and those that are immuno-compromised so we are focused on our higher risk patients,” she tells 10News.This week, 10News interviewed Dr. David Wetherhold at Scripps Health whose team is also trying to reach that same population through Scripps' telehealth program. It was supposed to roll out over the next 18 months, but with COVID-19, it's compressed into a few weeks. “The immuno-compromised, transplant patients, heart failure patients or cancer patients. [They’re] going to be our initial focus [with] trying to get them the care they need remotely without bringing them out into the community," Wetherhold said.RELATED: In-person EDD services temporarily closed“They are more at-risk of getting severe complications from coronavirus so we want to limit them coming into the office when we can,” adds Dr. Olulade. She wants to remind at-risk patients to stay in communication with their providers about any new symptoms, even if mild, that could warrant a need for further evaluation. If an office visit is required, she tells 10News that they'll prepare accordingly to receive those patients and limit any risks they could face. 1762