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Maryland-based vaccine developer, Novavax, has received .6 billion from the federal government to complete late-stage clinical development; set up large-scale manufacturing; and deliver 100 million doses of NVX?CoV2373, its COVID-19 vaccine candidate, as early as late 2020.This is the largest vaccine deal to date with the Trump administration as part of their Operation Warp Speed, which is focused on making a COVID-19 vaccine and treatments available as quickly as possible.Novavax has not brought any of their developed vaccines to market. According to information on their website, they have developed several vaccines for infectious diseases, however they are all in various stages of development or clinical trials. These include vaccines for the seasonal flu and RSV. Other vaccines created by Novavax are not actively being developed or studied at this time, including ones for Ebola, MERS, and SARS.According to a statement from Novavax, the agreement with the federal government includes the company demonstrating being able to rapidly get manufacturing and large-scale production of the vaccine going once approved. Novavax hopes to conduct their late-stage clinical study with 30,000 subjects in fall 2020.An early-stage clinical study took place in Australia in May on 130 participants. Study results are expected at the end of July.“Today’s .6 billion investment supports the Novavax candidate, depending on success in clinical trials, all the way through to manufacturing 100 million doses for the American people,” said U.S. Health and Human Services Secretary Alex Azar.Regeneron Pharmaceuticals has also received 0 million through Operation Warp Speed on Tuesday, to make and supply its COVID-19 vaccine candidate, REGN-COV2. Their vaccine is currently in phase 2 and phase 3 clinical studies for the treatment and prevention of COVID-19.Regeneron has several vaccines on the market currently, including Dupixent, used to treat allergic diseases such as eczema, asthma and nasal polyps which result in chronic sinusitis, and Praluent, used to treat high cholesterol. 2101
Maine’s Center for Disease Control and Prevention said that it has traced 24 COVID-19 cases from an August 7 wedding reception in Millinocket, Maine.According to data released by the Maine CDC, 18 of the 24 cases were among those who attended the wedding reception. An additional six cases were tied to close contacts of those who attended the gathering.The reception reportedly had 65 attendees.Maine’s CDC is conducting further contact tracing of those who attended or worked the reception.Maine currently limits indoor gatherings to 50 people and outdoor gatherings to 100 attendees. 594
Midterms, look what you made Taylor Swift do.In a rare move, singer Taylor Swift has weighed in on politics in a major way, endorsing Tennessee Democrats Phil Bredesen and Jim Cooper, who are running for Senate and House of Representatives, respectively.By her own admission, Swift has been "reluctant" to voice her political opinions in the past, but, she said in an Instagram post, "due to several events in my life and in the world in the past two years, I feel very differently about that now.""I always have and always will cast my vote based on which candidate will protect and fight for the human rights I believe we all deserve in this country," she wrote. "I believe in the fight for LGBTQ rights, and that any form of discrimination based on sexual orientation or gender is WRONG. I believe that the systemic racism we still see in this country towards people of color is terrifying, sickening and prevalent."Swift went after Bredesen's senate race rival, Republican Rep. Marsha Blackburn, in her post, saying the politician's voting record "appalls and terrifies me."Bredesen served as governor of Tennessee from 2003 to 2011.In a tweet, Bredesen thanked Swift for her "kind words.""I'm honored to have your support and that of so many Tennesseans who are ready to put aside the partisan shouting and get things done," he wrote. "We're ready for it.""The choice continues to be clear: voters can either have more of the same old partisan shouting that's coming out of D.C, or they can hire someone who has a track record of getting things done for Tennessee," Bredesen's campaign added in a statement to CNN.Swift included a plea to her young adult fans in her post, urging them to register before the deadline."So many intelligent, thoughtful, self-possessed people have turned 18 in the past two years and now have the right and privilege to make their vote count," she wrote. 1907
MARICOPA COUNTY, Ariz. – Arizona's most populated county will dismiss all pending and unfiled charges of possession of marijuana now that voters have passed Prop 207, which legalizes recreational marijuana in the state.The Maricopa County Attorney's Office made the announcement on Monday, nearly a week after residents voted on the measure. 350
MIAMI SHORES, Fla. (AP) — Authorities say a Florida police officer’s wife died after becoming trapped in the back of his patrol vehicle for several hours during a hot afternoon. Investigators are treating the death of 56-year-old Clara Paulino as an accident. She died Friday afternoon while her 58-year-old husband Aristides Paulino was sleeping in their Miami Shores home after finishing a midnight shift. The Miami Herald reports Paulino woke up around 5 p.m. and started looking for his wife, finding her cell phone on the back patio. He and one of his sons found Clara in the vehicle. Officials say she had climbed into the backseat of his marked SUV to find something when the doors somehow closed, and a self-locking mechanism engaged. The vehicle has a partition between the back seat and front seat, meaning Clara could not reach the horn. “It’s literally a cage,” one Miami police officer familiar with the vehicle told the Miami Herald.Temperatures reached over 90 degrees as she spent about four hours in the vehicle. 1037