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JUPITER, Fla. — Groundbreaking research out of the Scripps Research Institute in Jupiter, Florida found a genetic explanation for the pain processing and sensory issues some children living with autism face."To see the biology in the lab turn out that has parallels to what’s going on in these children takes it so far beyond just an academic endeavor," said Dr. Gavin Rumbaugh, a neuroscientist at Scripps. "You go home every day thinking, unbelievably, I may actually be making a difference in someone's life."One of those children who Rumbaugh hopes to help with his research is 10-year-old Beckett, who lives in Texas."We wanted to understand generally in the lab how genes like SYNGAP1 affect the way the brain functions and we thought what better way was then to look and see how this gene may directly affect sensory processing, and then further on ask the question, 'Does the change in sensory processing actually lead directly to learning, memory and behavioral impairment?' " he said.Beckett has a genetic mutation of SYNGAP1, which researchers have now found causes certain issues he faces, particularly, having an extremely high pain threshold while also experiencing heightened sensitivity to another kind of stimuli. Beckett and other children living with this genetic mutation also often have epilepsy."It's all about quality of life. Everybody deserves to live their best life and that's my mission," said Monica Weldon, Beckett's mom.Weldon said the research being done in Jupiter could change her son's life and the lives of hundreds of other children around the world with the same genetic abnormality and symptoms, some of whom whose families she's connected with online."That is the power I believe of a patient group that is motivated to find treatments for their loved ones," Weldon said. "Also, you've got scientists who are listening. They're willing to listen and they're willing to learn."The next step in Rumbaugh's research is to look at treating the symptoms from the genetic mutation. 2043

JACKSONVILLE, Fla. (KGTV) -- Audio captured inside a video game tournament in Jacksonville, Florida reveals the moments a mass shooting took place. Throughout what was a live stream, shots can be heard ringing out inside the facility where the event, known as the Madden 19 Tournament, was taking place. The Jacksonville Sheriff's Office confirmed Sunday afternoon that several people are dead, including one shooter. Authorities are searching for other possible shooters nearby. RELATED: 'Mass shooting' at Madden video game tournament in Jacksonville, Florida, authorities sayListen to the audio in the player below:WARNING: The video below contains graphic content. Authorities held a news conference Sunday afternoon. Watch the conference in the player below: 806

JULIAN (CNS) - Three Cal Fire San Diego firefighters suffered minor injuries while dousing a blaze at a home in a rural area southwest of Julian, authorities said Tuesday.The fire was reported shortly before 8:40 p.m. Monday at a home on Pine Ridge Avenue in the unincorporated Pine Hills community, Cal Fire San Diego Capt. Issac Sanchez said.When firefighters arrived at the scene, the home was fully engulfed in flames, but the home's residents were able to get out safely.Crews doused the blaze and had the flames knocked down by 10:20 p.m., the state agency reportedThree firefighters were taken to a hospital for treatment of minor injuries but were released back to duty that night, Sanchez said.The American Red Cross was called in to help the displaced residents arrange for temporary lodging. 810

Kamala Harris is projected to become the first female Vice President of the United States. She will also be the first Black and first South Asian to hold that office. Her husband, Doug Emhoff, will set his own historic precedent.Emhoff will become the first second gentleman of the country when Harris is sworn in. The spouse of the vice president is typically called the “second lady”, and Emhoff is the first male spouse in the country’s history.Harris’ spouse is an entertainment lawyer and partner at the firm DLA Piper, and has been for the last few years. He took a leave of absence after Harris joined Biden’s ticket so he could focus on the campaign trail, he said at the time.Saturday morning, Emhoff tweeted a picture of him hugging Harris saying, “So proud of you.” 784

KANSAS CITY, Missouri — A handcuffed man in police custody jumped to his death from a bridge on Interstate 435 just south of the Missouri River and the Missouri 210 exit, according to the Kansas City, Missouri Police Department. 246