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As the world waits for deliveries of Pfizer’s coronavirus vaccine, the pharmaceutical company is having to adjust their target after hitting supply chain obstacles, according to the Wall Street Journal.“Scaling up the raw material supply chain took longer than expected,” a company spokeswoman told the WSJ.Pfizer and partner BioNTech SE had hoped to ship out 100 million doses of their vaccine by the end of the year, that has now reportedly been cut to estimates of about 50 million.Two doses are needed for each person to be vaccinated.Pfizer did not elaborate on where the raw material shortfalls happened. They did say some raw materials in early production earlier this year did not meet their standards and they had to fix the issue.After the WSJ’s report, Pfizer’s stock price dropped and the S&P 500 fell slightly.The United Kingdom has granted emergency use of the Pfizer vaccine, and is expected to start administering doses soon. The FDA in the U.S. is considering a similar authorization, which could come later in December.As part of Operation Warp Speed, the U.S. Government has purchased 100 million doses of Pfizer’s vaccine, with an option to buy more.Roughly 20 million of those doses were expected by the end of the year once the FDA granted emergency use authorization. No word on how Pfizer’s shipping delays could impact this number.Pfizer says their production lines in the U.S. and Europe are complete and they are “confident” they will supply the targeted number of doses in early 2021. 1524

As novel coronavirus cases soar across the country, states are struggling to keep up with the demand for testing. Some states are reporting big backlogs and difficulty getting tests.“We need to actually continue doing a bunch of work in America to figure out additional approaches to do testing,” said Dr. Bob Kocher.Dr. Kocher is the former co-chair of California's Testing Task Force. The state formed the team back in March to figure out how to get everyone tested. Back then, they were struggling to do 2,000 tests a day. Now, they're doing more than 100,000 a day.“California, and most states, had giant shortages of the world’s most expensive Q-tips, called swabs, that you need to collect the samples and the people who make them couldn’t make more of them,” Dr. Kocher explained. “We worked with companies to 3-D print them and to source those from other places in the world and buy them and bring them to California.”They worked to find labs that could do high-capacity testing and expanded the number of testing sites. But as cases increased across the state and nation, five months into the pandemic, testing turnaround time is an issue.“It’s something I’m concerned about as demand for testing grows everywhere in the country and on the earth, the labs are going to sporadically have backlogs, and over time, they could have backlogs because it’s hard to make more supply of the test,” Dr. Kocher said.Dr. Kocher says it depends on where the test is sent. Some labs have backlogs and it’s a logistics issue. If the lab your test site is using is in another part of the country, it'll likely take longer to get results.In a statement, Quest Diagnostics said, "We are grappling with surging demand that is outpacing capacity. This is due to surging cases of COVID-19 across much of the United States, particularly the West, Southwest and South. We have a prioritization program to help direct testing to patients most in need. Our turnaround time for priority one patients is 1 day on average."In a recent press conference, California's Health and Human Services Agency Secretary Dr. Mark Ghaly said supply chain challenges forced the state to prioritize who gets tested first.“Surges across the nation have created challenges of getting tests processed, not just collected, and ensuring our guidelines not only say who needs to be tested but give guidance to labs on which specimens to process first,” Dr. Kocher said.Right now, priority means those who are hospitalized, healthcare workers, first responders, social service employees, those who are 65 and older and those with chronic medical conditions. But, we simply need more tests.“The challenge with COVID-19 is that each person infects two, three more people and that leads to exponential growth of people who are infected and exponential growth in demand for testing,” Dr. Kocher said. “The companies who manufacture tests have been extraordinary scaling up their capacity to manufacture tests they can grow them by 10, 30 maybe a 100 percent, but the demand for COVID testing is growing 1,000 percent.”The American Clinical Laboratory Association which represents Quest and other labs released a statement saying many labs are getting more test orders than they're able to process in a single day.In a statement, the company said, "We can’t do it alone. Laboratories, diagnostic manufacturers, ordering providers, public health officials, states and importantly, the federal government – including Congress and the Administration – all have a role to play in addressing the challenges hampering our nation’s response to this public health crisis."The test, Dr. Kocher says, only tells you if you're infectious at the time you were tested. It's yet another hurdle for states to tackle."So, we need to figure out what is the mechanism to test people at the right frequency to make us all safe and fell confident in going to work, school, nursing home or being an essential worker,” he said. “It’s really important.”Figuring out what that looks like means looking at new technologies, getting the government involved and working on our manufacturing sector so we have more tests and fewer logistical problems as we consistently try to keep up with the virus that seems to be one step ahead of us all. 4276

Atlanta Dream point guard Renee Montgomery is opting out of the 2020 WNBA season to focus on social justice reform after the death of George Floyd in Minneapolis.Montgomery tweeted her decision on Thursday."After much thought, I’ve decided to opt-out of the 2020 WNBA season. There’s work to be done off the court in so many areas in our community. Social justice reform isn’t going to happen overnight but I do feel that now is the time and Moments equal Momentum. Let's keep it going!" 495

At first glance, you may not notice what's different about this box of cereal. Maybe it's just one of those special editions that's in stores for a short time. But if you take a closer look you might ask, what's up with that?When Naomi Frierson walked into her local Walmart and down the aisle, her focus was getting her mom a box of her favorite cereal."I just picked it up and I kind of looked at it," Frierson said. "And I figured it was one of those special edition type of boxes. ... I didn't think much of it."But when she got home, her husband noticed."We proceed to look at it further and realize that not only are there mugshots but they're serial killers," Frierson said. "Not the C-E-R-E-A-L kind unfortunately."The box of "Life" cereal is covered with people synonymous with death. Larry, the Quaker Oats mascot is Jeffrey Dahmer. And instead of being made with 20 whole grains, it's made with 20 whole brains."And then on the nutrition panel you've got stuff like instead of cholesterol it says chloroform," Frierson said. "Down here it says cyanide."Frierson said she was creeped out, but her husband loved it."He immediately recognized all of the different players in the game," Frierson said. "And he thought it was just the coolest thing ever and assured me that it must be art."He was right. The box was a class project made by Lauren Miller, a senior art student at the University of South Florida."I kind of just wanted it to blend in with everything else," Miller said. "I took a bunch of pictures that I found online of serial killers and I used Photoshop to add them to the Life cereal box. I just thought it would be interesting to use Life cereals since these people did take away lives."Miller has a large version of the box in her studio but wanted to see how people reacted to this smaller version in the community.Frierson said, "I had people on my personal Facebook when I posted that thing like, 'Oh my gosh I need to have that. How can I get one? Are there more?'"Frierson said she's keeping this box, and Miller is exploring creating more to sell.Miller said she left a note on the box saying it was art and had already been paid for. But for Frierson, the initial jitters and overall experience was well worth the price."I think (it was) three dollars well spent for an interesting piece of art," Frierson said.A creepy class project, taking on a life of its own."I would say a solid 'A' so if you didn't get an 'A' I'll call your professor," Frierson said. 2539

ATLANTA (AP) — NASA astronaut Kate Rubins told The Associated Press on Friday that she plans to cast her next vote from space – more than 200 miles above Earth. Rubins and two cosmonauts are in Star City, Russia, just outside Moscow. She's preparing for a mid-October launch and a six-month stay at the International Space Station.Texas law allows U.S. astronauts to vote from space using a secure electronic ballot. Mission Control in Houston forwards the ballot to the space station, which Rubins then emails to the county clerk. 539

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