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WASHINGTON, Sept. 12 (Xinhua) -- An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and alcohol abuse in people, U.S. researchers find.Over the course of four weeks, mice genetically engineered to lack the gene for protein kinase C (PKC) epsilon consumed less of a nicotine-containing water solution than normal mice, and were less likely to return to a chamber in which they had been given nicotine. In contrast, normal mice steadily increased their consumption of nicotine solution while the mice lacking PKC epsilon did not.The study conducted by researchers at the Ernest Gallo Clinic and Research Center, affiliated with the University of California, San Francisco, appeared Monday in the online edition of the Proceedings of the National Academy of Sciences.In normal mice, as in humans, nicotine binds to a certain class of nicotinic receptors located on dopamine neurons, which causes dopamine to be released in the brain. Dopamine creates a feeling of enjoyment, and thus prompts a sense of reward. Researchers found that mice lacking PKC epsilon are deficient in these nicotinic receptors.The finding complements earlier research in which researchers found that mice genetically engineered to lack the PKC epsilon enzyme drank less alcohol than normal mice and were disinclined to return to a chamber in which they had been given alcohol."This could mean that these mice might not get the same sense of reward from nicotine or alcohol," said Gallo senior associate director and investigator Robert Messing. "The enzyme looks like it regulates the part of the reward system that involves these nicotinic receptors."The reward system is a complex of areas in the brain that affect craving for nicotine, alcohol and other addictive substances.The next step in the research, said Messing, would be to develop compounds that inhibit PKC epsilon. The ultimate goal, he added, would be medications that could be used "to take the edge off of addiction by helping people get over some of their reward craving."

LOS ANGELES, July 5 (Xinhua) -- NASA's Juno spacecraft is 30 days away before its first launch window opens, the Jet Propulsion Laboratory (JPL) announced on Tuesday."One month from today, our first launch window opens at 11:34 a. m. EDT (8:34 a.m. PDT) and lasts 69 minutes," said Jan Chodas, Juno project manager from NASA's JPL in Pasadena, Los Angeles."Our primary launch period is 22 days long, and so if weather or other issues come up on Aug. 5, we have 21 more days to get Juno flying. Once we get Juno into space, it's a five-year cruise to Jupiter.""The launch window is the length of time allotted every day for an attempt to launch the spacecraft," said Chodas. "The launch period is the period of time in days when everything is in the right place to get your mission off to the right start."For a mission like Juno, getting everything in the right place includes considering the size of the rocket and spacecraft, where our home planet -- and in particular Juno's launch pad -- is pointed at any moment, and its location in space relative to other celestial objects like Juno's final target, Jupiter.Juno is scheduled to launch aboard a United Launch Alliance Atlas V rocket from pad 41-C at the Cape Canaveral Air Force Station, Florida.The solar-powered spacecraft will orbit Jupiter's poles 33 times to find out more about the gas giant's origins, structure, atmosphere and magnetosphere and investigate the existence of a solid planetary core.JPL manages the Juno mission for the principal investigator, Scott Bolton, of Southwest Research Institute in San Antonio.The Juno mission is part of the New Frontiers Program managed at NASA's Marshall Space Flight Center in Huntsville, Alaska. Lockheed Martin Space Systems, Denver, built the spacecraft.

LOS ANGELES, July 6 (Xinhua) -- NASA scientists have got the first-ever, up-close details of a Saturn storm that is eight times the surface area of Earth, the Jet Propulsion Laboratory ( JPL) announced on Wednesday.The images were captured by NASA's Cassini spacecraf, according to JPL in Pasadena, Los Angeles.On Dec. 5, 2010, Cassini first detected the storm that has been raging ever since. It appears approximately 35 degrees north latitude of Saturn.The storm is the biggest observed by spacecraft orbiting or flying by Saturn. NASA's Hubble Space Telescope captured images in 1990 of an equally large storm.Pictures from Cassini's imaging cameras show the storm wrapping around the entire planet covering approximately two billion square miles (4 billion square kilometers).The storm is about 500 times larger than the biggest storm previously seen by Cassini during several months from 2009 to 2010. At its most intense, the storm generated more than 10 lightning flashes per second.Cassini has detected 10 lightning storms on Saturn since the spacecraft entered the planet's orbit.Those storms rolled through an area in the southern hemisphere dubbed "Storm Alley." "Cassini shows us that Saturn is bipolar," said Andrew Ingersoll, a Cassini imaging team member at the California Institute of Technology in Pasadena, California. "Saturn is not like Earth and Jupiter, where storms are fairly frequent. Weather on Saturn appears to hum along placidly for years and then erupt violently. I'm excited we saw weather so spectacular on our watch."The new details about this storm complement atmospheric disturbances described recently by scientists using Cassini's composite infrared spectrometer and the European Southern Observatory's Very Large Telescope. The Cassini-Huygens mission is a cooperative project of NASA, the European Space Agency and the Italian Space Agency. NASA's JPL manages the mission for the agency's Science Mission Directorate in Washington.

WASHINGTON, July 8 (Xinhua) -- U.S. President Barack Obama on Friday hailed space shuttle Atlantis' final flight in NASA's shuttle program, saying Americans across the country watched with pride as America reached for the heavens once more.Obama expressed his "sincere gratitude" to Atlantis astronauts and space workers because they "helped our country lead the space age.""Today's launch may mark the final flight of the space shuttle, " Obama said in a statement. "But it propels us into the next era of our never-ending adventure to push the very frontiers of exploration and discovery in space."Friday's flight is the 33rd voyage for Atlantis. Its return to the earth later this month will mark the end of the 30-year shuttle program."What a truly awesome day today," said NASA Associate Administrator for Space Operations Bill Gerstenmaier at the STS- 135 postlaunch news conference. "What you saw is the finest launch team and shuttle preparation teams in the world.""It truly was an awesome, spectacular launch," added Kennedy Space Center Director Bob Cabana, who looked ahead to plans for future development beyond the shuttle program as space station operations continue.Atlantis will be the last shuttle to be retired. Discovery was first in March, followed by Endeavour at the beginning of June. Each shuttle will head to a museum.When the U.S. space shuttle program officially ends later this year, the Russian space program's Soyuz capsule will be the only method for transporting astronauts to and from the station.

BEIJING, Aug. 24 (Xinhuanet)-- A new study shows that a diet rich in cholesterol-friendly foods, such as soy products and tree nuts, can decrease LDL (bad) cholesterol significantly, according to media reports on Tuesday.The study, published in the Journal of the American Medical Association, found that people who ate a healthy diet filled with cholesterol-lowering foods experienced a 13 percent decrease in their LDL cholesterol levels.For patients with high levels of so-called bad cholesterol, doctors usually have two prescriptions: cholesterol-lowering statin drugs and a diet that cuts out foods high in saturated fat, such as ice cream, red meat and butter.But the new study found that when it comes to lowering artery-clogging cholesterol, what you eat may be more important than what you don't eat.David Jenkins of St. Michael's Hospital and the University created the "portfolio diet," which includes regular consumption of tree nuts and high amounts of fiber from oats, barley and vegetables. The diet, which replaces butter with plant sterol-enriched margarine and substitute soy-based products for meat, allows maximum benefit in lowering cholesterol and preventing heart disease. "The study highlighted the power of food to lower risk for cardiovascular disease: What you do eat and what you don't eat are both important," said Dr. Jane Klauer, a New York internist specializing in metabolism and nutrition.A high overall cholesterol level makes a person nearly twice as likely to suffer a heart attack or stroke as someone whose total cholesterol falls into a healthy range.