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LOS ANGELES, June 5 (Xinhua) -- A latest study has found no evidence that screening for ovarian cancer may reduce the risk of dying from the disease, it was reported on Sunday.Screening, however, does increase the likelihood of unnecessary invasive procedures, according to researchers at the University of Utah.The researchers presented their findings at an on-going meeting of the American Society of Clinical Oncology in Chicago, The Los Angeles Times said.Researchers studied 78,216 women, ages 55 to 74, who participated in the National Cancer Institute's Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Half of the women received the usual care from their OB-gyns, and half received a CA 125 screening every year for six years and an ultrasound every year for four years. They were then followed for a maximum of 12 years.The researchers observed 212 ovarian cancers in the screened group and 176 in the normal care group. There were 118 ovarian cancer deaths in the screened group and 100 in the normal care group. The differences were not statistically significant. Overall, there were 2,924 deaths from all causes in the screened group and 2,914 in the normal care group.But the researchers also observed that 3,285 women had false- positive diagnoses from the screening. Among those, 1,080 underwent surgery that included an oophorectomy (surgical removal of one or both ovaries). Fifteen percent of those who had surgery developed major complications as a result. Overall, 1,771 women in the screened group (7.7 percent) had an oophorectomy, compared with 1,304 in the normal care group (5.8 percent)."We conclude that annual screening for ovarian cancer ... does not reduce disease-specific mortality in women at average risk for ovarian cancer but does increase invasive medical procedures and associated harms," the researchers said in the study.New data presented at the meeting also showed that the widely used cancer drug Avastin can improve treatment of ovarian cancer, The Times said.About 21,880 American women are diagnosed with ovarian cancer each year and about 13,850 die from it, according to the American Cancer Society. Because it produces few symptoms, the disease is typically not diagnosed until it has become advanced and spread throughout the body. As a result, five-year survival is only about 30 percent, and the disease is one of the five most deadly cancers among women. Being able to detect the cancer at an earlier stage when it might be more curable could thus, theoretically, improve the survival rate.The tests most commonly used to detect ovarian cancer include a transvaginal ultrasound to look for tumor masses and a blood test that screens for increased levels of a tumor marker called CA 125.

BERLIN, June 6 (Xinhua) -- The German authorities said on Monday that Germany's first sample tests of the allegedly contaminated bean sprouts have found no E. coli strains that have sickened more than 2,000 people in Europe.According to a statement issued by the Agriculture Ministry of the Lower-Saxony state, 23 of 40 samples concerning the suspected sprouts from a market garden in the state have tested negative, and further tests are still pending."Based on the initial findings in tests of some of the samples, especially the seeds, we assume that intensive analytical efforts are needed to prove that the suspected pathogen is really there," the statement said.Beansprouts and salad sprouts are seen in this picture illustration taken in Berlin June 6, 2011.  The German authorities said on Monday that Germany's first sample tests of the allegedly contaminated bean sprouts have found no E. coli strains that have sickened more than 2,000 people in EuropeLower-Saxony's Agriculture Minister Gert Lindemann said Sunday that a market garden in the rural district of Uelzen had provided a connection "involving all the main outbreaks" of the disease.Restaurants and food outlets of almost all E. coli-affected areas had received shipments of sprouts directly or indirectly from the company, state officials said.The German authorities have been racing to track down the source of the pathogen since the outbreak, which has infected people in 12 countries, all of whom had once traveled in northern Germany.More than 600 of those infected have developed Hemolytic Uremic Syndrome, a potentially deadly complication attacking the kidneys.The E. coli source was first thought to be cucumbers from Spain, which has caused huge loses for Spain farmers. However, this conclusion was overthrown by laboratory tests in Hamburg later.

BEIJING, July 25 (Xinhuanet) -- Apple is planning a third, even larger Shanghai store, as well as dozens of other stores throughout China, to cope with huge crowds at its flagship store and a branch, according to media reports Monday.Apple says its Chinese outlets -- two in Beijing and two in Shanghai -- are the four most heavily trafficked Apple stores in the world. They also generate the most revenue. Apple’s push into China shows the depth of the country’s fast-growing economy, and shows that with products not so easy to counterfeit, Chinese consumers are willing to pay a premium.For the first three quarters of Apple’s fiscal year, revenue in China and its Taiwan, Hong Kong was 8.8 billion dollars -- six times that of a year earlier. China has become the second-largest market, after the United States, for apps that run on the smartphone and tablet, according to Distimo, a Dutch company that tracks the popularity of apps.In addition, Apple has been eager to team up with state-run telecom companies, which looks after mobile phone subscriptions.

BEIJING, June 3 (Xinhua) -- Google lacked evidence to support its accusations that Chinese hackers are behind the alleged cyber attacks on hundreds of its email accounts and the timing to make such accusations is evil-intentioned, Chinese experts said on Friday."Google's accusation is neither serious nor credible as it has not published any evidence that shows the hackers are from China," said Dai Yiqi, a cyber security expert with Tsinghua University.Eric Grosse, engineering director of Google's Security Team wrote on the company blog Wednesday that unidentified hacker attacks likely originated from the eastern Chinese city of Jinan, tried to collect user passwords of the Gmail accounts of hundreds of users, including senior U.S. government officials, Chinese "human rights activists" and journalists.A report released in 2009 by the United States-China Economic and Security Review Commission, an organization created by the U.S. Congress, claimed that Jinan is the home of a Chinese military reconnaissance office.An anonymous cyber security expert believes, despite Google not referring to the Chinese government in the latest attack claim, the company is targeting the Chinese government by listing the victims of the attacks as those whom only the Chinese government are interested in."Both their intentions and the timing of the accusation are dubious," Dai said.Google's accusation followed on the heel of the reported Pentagon's first formal cyber strategy. The Wall Street Journal reported Tuesday that the Pentagon concluded that computer sabotage coming from another country can count as an act of war and the United States may respond by using traditional military force.Li Shuisheng, a research fellow with a top military science academy of the People's Liberation Army, believes there are political motives behind Google's accusation.Google may well have attempted to instigate a new round of the cyber row between China and the United States, Li said.Wednesday's accusation by Google came more than a year after the company allegedly uncovered a cyber attack on its systems that it said it traced to China.In January, 2010, Google said it had been attacked by hackers supported by the Chinese government, and later announced to withdraw from Chinese mainland. The row ended up with Google redirecting Chinese mainland users to a site in Hong Kong.In such cyber attacks, it is easy to locate the IP address of hackers but hard to tell where the hackers actually are, said Dai."Hackers usually launch attacks by camouflaging their own IP addresses or controlling computers of others. Therefore, we can hardly tell the location of the hacker unless we have sufficient evidence," he said.China is one of the leading targets of cyber attacks. It has the world's largest number of computers infected with bot, a type of malware which allows a cyber attacker to gain control over the affected computer.About 13 percent of the world's computers infected with bot are in China."Without cooperation between governments, absolute security cannot be guaranteed in cyber community," said Li , adding only cooperation can ensure safe information exchange.

SINGAPORE, Sept. 7 (Xinhua) -- Singapore scientists have found possible new ways to treat a type of aggressive breast cancer that is unresponsive to current forms of treatment, local broadcaster Channel NewsAsia reported on Wednesday.The team of scientists at the Genome Institute of Singapore ( GIS) and National University of Singapore (NUS), led by GIS senior group leader Qiang Yu, found that the enzyme EZH2 acts by inhibiting genes that stop the growth of tumors in the body.The insights could open the door to developing more effective treatment for fast spreading breast cancers, especially the estrogen receptor-negative breast cancer that is common all over the world.It was also found that through EZH2, cancer is promoted in the body by activating specific genes that impact breast cancer progression and cancer stem cell self-renewal.Yu said the new understanding on how EZH2 works as a cancer- causing gene in breast cancer has important therapeutic implication."The results suggest that small molecule drugs that block enzyme activity of EZH2 may not work for cancers caused by EZH2's activation genes," Yu said.Currently pharmaceutical companies have been developing drugs only to the block EZH2 enzyme activity so that tumor suppressers can perform their protective role in blocking cancer growth.Researchers said the next step would be to develop biomarkers to identify tumors with EZH2.This step would enable better treatment methods, with one of options being the development of therapies that shut down EZH2 completely and not just inhibit its enzymatic function.The findings have been published on the journal Molecular Cell.

来源：资阳报