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WASHINGTON, May 11 (Xinhua) -- Johns Hopkins University researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.The work, published Wednesday in the journal Science Translational Medicine, suggests that liver cells derived from so- called "induced-pluripotent stem cells (iPSCs)" could one day be used as an alternative to liver transplant in patients with serious liver diseases, bypassing long waiting lists for organs and concerns about immune system rejection of donated tissue."Our findings provide a foundation for producing functional liver cells for patients who suffer liver diseases and are in need of transplantation," says Yoon-Young Jang, assistant professor of oncology at the Johns Hopkins Kimmel Cancer Center. "iPSC-derived liver cells not only can be generated in large amounts, but also can be tailored to each patient, preventing immune-rejection problems associated with liver transplants from unmatched donors or embryonic stem cells." A microsopic view shows human embryonic stem cells in various stages of differentiation into liver cells in this photo taken at Stanford University and released by the California Institute for Regenerative Medicine, March 9, 2009iPSCs are made from adult cells that have been genetically reprogrammed to revert to an embryonic stem cell-like state, with the ability to transform into different cell types. Human iPSCs can be generated from various tissues, including skin, blood and liver cells.Although the liver can regenerate in the body, end-stage liver failure caused by diseases like cirrhosis and cancers eventually destroy the liver's regenerative ability, Jang says. Currently, the only option for those patients is to receive a liver organ or liver cell transplant, a supply problem given the severe shortage of donor liver tissue for transplantation. In addition, mature liver cells and adult liver stem cells are difficult to isolate or grow in the laboratory, she says. By contrast, iPSCs can be made from a tiny amount of many kinds of tissue; and the embryonic stem- like iPSCs can grow in laboratory cultures indefinitely.For the study, Jang and colleagues generated human iPSCs from a variety of adult human cells, including liver cells, fibroblasts ( connective tissue cells), bone marrow stem cells and skin cells. They found that though the iPSCs overall were molecularly similar to each other and to embryonic stem cells, they retained a distinct molecular "signature" inherited from the cell of origin.
LOS ANGELES, May 20(Xinhua)-- Peter, a Chinese American who works for the post office in Rosemead, California, said he has been attacked by dogs twice in the past 10 years while delivering mails.He said as a mail carrier, he has to walk door to door to put mails into the mailboxes of the residents, and many times the owners were not at home but their dogs were too loyal to their duties and would see mail carriers like him as intruders."It is dangerous to be a mail carrier. The enemy is not humans but animals like dogs who have been generally seen as human's best friends," Peter, who asked not to identify his full name, told Xinhua.Mail carriers in the United States feel the real danger of being attacked by dogs while delivering mails door by door.Statistics released by the U.S. Post Office showed that 5,669 postal employees were attacked by dogs in 2010 in the United States. That's an average of 11 dog attacks every delivery day, and that figure does not include the number of threatening incidents that did not result in injury.Los Angeles is the third most dangerous city in the U.S. when it comes to being a mail carrier with 44 mail carriers being attacked by dogs in 2010, according to the U.S. Post Office.San Diego in California and Columbus in Ohio tied for second place, each logging 45 dog attacks. Houston in Texas is the most dangerous city in the U.S. for mail carriers with 62 attacks in 2010.On May 25, 2010, Eddie Lin, a 33-year old Chinese American postal carrier in San Diego, was attacked by a dog while delivering mail, his head hit on the ground and died 10 days later. His death angered his family and the whole community.The daughter of the dog's owner, who identified herself as Eva, said the incident has devastated her father."We feel really bad," Eva told the local press in an interview. "It's just killing my Dad," she added.On Sept. 30, 2010, a German Shepard and a Pitbull mix attacked Hu Ruiz, a 10-year veteran of the U.S. Postal Service. He luckily recovered from puncture wounds on his arms after the two dogs attacked him as he made deliveries along Camden Avenue in San Jose, California.It is not the problem for the mail carriers only. Dogs attack other people too. Statistics showed that there are more than 4.7 million Americans bitten by dogs nationwide annually.
BEIJING, Jan. 26 (Xinhua) -- China remained a major victim of trade protectionism during the past year, witnessing 64 trade disputes in this period, covering some 7 billion U.S. dollars in value, China's Vice Commerce Minister, Zhong Shan, said here Wednesday.The country faced trade disputes with both developed countries and developing ones, which came from not only traditional sectors but also high-tech industries, he told a national conference on trade promotion.For the short- and mid-term, China would work to maintain a stable growth in foreign trade and keep the growth rate higher than both the global level and China's economic growth, he said.China would also strive to achieve a more balanced trade structure by boosting imports and outbound investment, to strengthen the quality and efficiency of foreign trade, he added.China's foreign trade last year jumped 34.7 percent year on year to more than 2.97 trillion U.S. dollars, while its trade surplus fell 6.4 percent to 183.1 billion U.S. dollars.
BEIJING, Feb. 26 (Xinhua) -- China's Ministry of Education said Friday that 34.29 million students graduated from the country's higher-learning institutions between 2006 and 2010.Xu Mei, the ministry's spokeswoman, said the number is even more than that of the graduates in the 20 years prior to 2006 combined."During the 11th five-year plan period (2006-2010), higher education has become even more accessible to the general public. Higher-learning institutions provide a strong support of brain power and human resources to the social and economic development," Xu said.The "Outline of China's National Plan for Medium and Long-Term Education Reform and Development (2010-2020)," which was publicized last year, says "the strategic goals to be attained by 2020 are to basically modernize education; shape a learning society; and turn China into a country rich in human resources."
BEIJING, March 24 (Xinhuanet) -- Mozilla's newly launched Firefox 4 Web browser was downloaded nearly 7 million times worldwide in the first 24 hours, according to media reports.The number was almost triple the 2.4 million downloads that Microsoft reported in the first 24 hours after the Internet Explorer 9 (IE9) was released.Nevertheless, the number lagged behind the record-breaking performance of Firefox 3, which was downloaded more than 8 million times in the first day after launch in mid-2008.Statistics show that Firefox 4 has attracted interest from around the world, with 44 percent downloads in Europe, 26 percent in North America. and 20 percent in Asia.Mozilla launched Firefox 4 on Tuesday at around 10:00 a.m. EDT to compete with Microsoft's IE9 and Google Chrome.The new Web browser was originally scheduled to ship last November, but bugs delayed the release into early this year.Firefox trumped IE9 in the first day download contest because it runs on Windows XP, the 10-year-old operating system that IE9 doesn't support.