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Moderna announced on Thursday that it had enrolled 30,000 participants in its Phase 3 COVID-19 vaccine trial, with more than 11,000 of those participants from communities of color.More than 25,650 participants have already received their second vaccination, the company said in a press release.The company added that the study also includes 7,000 participants over the age of 65.“Completing enrollment of the Phase 3 COVE study is an important milestone for the clinical development of mRNA-1273, our vaccine candidate against COVID-19," said Stéphane Bancel, Chief Executive Officer of Moderna in the news release. "We are indebted to all of the participants in the study. We would also like to thank the investigators and our partners at clinical trial sites, including our partners from PPD and the NIH, as well as the dedicated Moderna team for their support in completing enrollment. Moderna is committed to rigorous scientific research and the highest data quality standards. We will continue to work in collaboration with regulators to advance mRNA-1273, which we hope will help defeat the COVID-19 pandemic.”CNN reported that for Moderna to apply to the FDA for emergency use authorization, the following three things need to happen:53 of the 30,000 participants would need to become sick with COVID-19, which is expected to occur in the second half of November.40 of the 53 participants who do become ill with COVID-19 need to have received the placebo, which would show that the vaccine is 75% effective.Make sure enough time has passed to see if participants develop side effects.According to CNN, Moderna is the first company to start US clinical trials of a COVID-19 vaccine. 1696
Missouri Gov. Eric Greitens, who was indicted on a felony charge last month, is showing no sign that he will back down in the face of the scandal, running a radio ad this weekend touting his conservative mission and saying he "won't stop until the mission is complete."The ad, paid for by Greitens' campaign, does not explicitly address the controversy surrounding the Republican governor, but says liberals are "hell-bent on stopping his conservative reforms.""Even Satan's own lawyers from the Satanic Temple are suing Greitens," the narrator of the ad says in reference to a lawsuit by the Satanic Temple against the state of Missouri over its abortion laws.The governor's campaign has so far put ,000 behind the spot, according to one source with knowledge of the buy. It is set to air Thursday through Tuesday, coinciding with the Easter holiday."Eric Greitens is on a conservative mission for Missouri," the ad concludes, "and he won't stop until the mission is complete."Greitens was indicted in February on an invasion of privacy charge stemming from an extramarital affair he had in 2015. Greitens has admitted to the affair but denied breaking the law.The indictment against Greitens alleges he photographed a person in "full or partial nudity" without the person's knowledge or consent."Greitens then transmitted that image "in a manner that allowed access to that image via a computer," the indictment alleges.Greitens, who has been accused of blackmailing the woman with whom he was having an affair, has denied the charge, saying in a statement in February, "As I have said before, I made a personal mistake before I was Governor. I did not commit a crime."Democrats and some Republicans have called for his resignation and the Republican-led state House has opened an investigation into the charges against Greitens.Attorney General Josh Hawley's office has also announced that they are probing Greitens' veterans charity. 1948

National security adviser H.R. McMaster has agreed to resign and will be replaced by former US ambassador and Fox News analyst John Bolton, President Donald Trump announced in a tweet on Thursday."I pleased to announce that, effective 4/9/18, @AmbJohnBolton will be my new National Security Advisor. I am very thankful for the service of General H.R. McMaster who has done an outstanding job & will always remain my friend. There will be an official contact handover on 4/19.""The two have been discussing this for some time. The timeline was expedited as they both felt it was important to have the new team in place, instead of constant speculation," a White House official said. "This was not related to any one moment or incident, rather it was the result of ongoing conversations between the two."Bolton is a stalwart of Republican national security circles known for his hawkish views."After 34 years of service to our nation, I am requesting retirement from the U.S. Army effective this summer after which I will leave public service. Throughout my career it has been my greatest privilege to serve alongside extraordinary servicemembers and dedicated civilians," McMaster said in a statement released by the White House."I am thankful to President Donald J. Trump for the opportunity to serve him and our nation as national security advisor. I am grateful for the friendship and support of the members of the National Security Council who worked together to provide the President with the best options to protect and advance our national interests," the statement said. 1589
NASA astronauts Shannon Walker, left, Victor Glover, second from left, Mike Hopkins, second from right, and Japan Aerospace Exploration Agency (JAXA) astronaut Soichi Noguchi, right, wearing SpaceX spacesuits, stop to pose for a picture as walk out of the Neil A. Armstrong Operations and Checkout Building to depart for Launch Complex 39A during a dress rehearsal prior to the Crew-1 mission launch, Thursday, Nov. 12, 2020, at NASA’s Kennedy Space Center in Florida. 478
More than four and a half million children live in a home with an unlocked, loaded gun. Three out of 4 of those kids know where the firearms are kept in their house.The “End Family Fire” campaign released this week highlights the importance of safe gun storage in a home in order to keep children safe.Every day, 8 children and teens--ages 19 and under--are unintentionally shot by weapons that are found in the home.Hector Adames' nephew, Joshua, was one of them.“Joshua was shot in the stomach; [it] went through his stomach,” says Adames. “And unfortunately, when Joshua went down, he never got back up.”Kyleanne Hunter, with the Brady Center to Combat Gun Violence says it’s a tragedy that could be prevented by properly storing weapons.The nonprofit organization is the group behind the “End Family Fire” campaign. Hunter says they don’t want to confiscate guns, but instead encourage parents to keep guns locked up, keep ammo separate and let family and visitors know there are firearms in the home and locked away.It's advice Adames hopes parents will take.“We just want to try to prevent any family from having the same kind of pain that this has put my family through. 1185
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