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U.S. government officials are putting an early end to a study testing an Eli Lilly antibody drug for people hospitalized with COVID-19 because it doesn’t seem to be helping them.Independent monitors had paused enrollment in the study two weeks ago because of a possible safety issue. But on Monday, the National Institute of Allergy and Infectious Diseases, which sponsors the study, said a closer look did not verify a safety problem but found a low chance that the drug would prove helpful for hospitalized patients.It is a setback for one of the most promising treatment approaches for COVID-19. President Donald Trump received a similar experimental, two-antibody drug from Regeneron Pharmaceuticals Inc. on an emergency basis when he was sickened with the coronavirus earlier this month.In a statement Lilly notes that the government is continuing a separate study testing the antibody drug in mild to moderately ill patients, to try to prevent hospitalization and severe illness. The company also is continuing its own studies testing the drug, which is being developed with the Canadian company AbCellera.Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. The experimental drugs are concentrated versions of one or two specific antibodies that worked best against the coronavirus in lab and animal tests.Lilly and Regeneron have asked the U.S. Food and Drug Administration to grant emergency use authorization for their drugs for COVID-19 while late-stage studies continue. Lilly says its request is based on other results suggesting the drug helps patients who are not hospitalized, and that it will continue to seek the FDA’s permission for emergency use.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 1928

TUCSON, Arizona — Ballot counting continues across Arizona Friday in a Senate race separated by only a few thousand votes, and less than one percent.With hundreds of thousands of ballots left to be counted, it may be days before Arizonans know whether Republican Martha McSally or Democrat Kyrsten Sinema won the race to replace Jeff Flake in the upper chamber of Congress.But there's one not-unlikely scenario in which Arizonans may be represented by both Congresswomen in the Senate.After John McCain's passing in August, the responsibility fell to Arizona Republican Gov. Doug Ducey to appoint an interim replacement for the beloved senator in Washington. Ducey made a safe choice in former Arizona Sen. Jon Kyl, who retired from office in 2013. Kyl, however, only committed to serve in the role until early January, after which Ducey will once again have to choose a replacement until Arizonans make their choice to fill the seat in a 2020 special election.So who are the potential candidates? There was speculation over the summer that Ducey might appoint his own chief of staff to the role or even Cindy McCain -- the Arizona senator's widow. But should Sinema eek out a win after ballot counting is completed, McSally will be out of a job, having vacated her seat in Congress to campaign.If Ducey decides to appoint McSally, that could leave both candidates serving in the Senate until at least 2020. After that, the Republican appointee will have to decide whether or not to run in the special election.Ducey has left no indication so far about his intentions for the appointment, but McSally's name certainly isn't out of the picture. 1691

UPDATE: Suspect Brandon Alexander is in custody, and the Xavier Alexander and his mother are safe, Upland police say. They were found in Claremont, California, just west of Upland.SAN DIEGO (KGTV) - A 15-month-old child is missing, and police are looking for the child's father in connection with the abduction.The California Highway Patrol issued an Amber Alert Saturday night for a 2017 grey Jeep Renegade, California license plate 8DQT883.Authorities believe 31-year-old Brandon Alexander, may have kidnapped his son, 15-month-old Xavier Alexander. The pair were last seen at 5:45 a.m. Saturday in Upland, California, which is in San Bernardino County. Brandon Alexander is considered to be armed and dangerous.Brandon Alexander may have also taken the child's mother, according to Upland Police. Police say she is a white female in her early thirties. She has a restraining order against him, police said.Brandon Alexander is described as 5' 10" and 240 pounds with brown hair and blue eyes. Xavier Alexander is 2' 6" and weighs 30 pounds, also with brown hair and blue eyes. The Amber Alert was issued in Kern, Inyo, San Bernardino, Los Angeles, Ventura, Orange, Riverside, Imperial and San Diego counties.Anybody who sees the vehicle or Brandon and Xavier Alexander are asked to call 9-1-1.10News is monitoring this breaking situation. 1369

Vice President Mike Pence formally accepted the Republican nomination for vice president on Wednesday, as he will join Donald Trump for a bid at a second term in the White House.Pence delivered his speech from Fort McHenry in Baltimore, Maryland, in front of a small group of supporters. The GOP convention has largely been held remotely in Washington, DC, after the party canceled most activitiesPence addresses unrestPence, who was not expected to address the growing unrest in Kenosha, Wisconsin, and elsewhere following the shooting of Jacob Blake decried violence at the demonstrations, Pence reiterated that the Trump administration will ensure law and order.Protests continued on Wednesday as pro athletes from the MLS, MLB and NBA sat out in solidarity with the demonstrations.Blake was shot seven times on Sunday by Kenosha Police officer Rusten Sheskey, who has since been placed on administrative leave. Sheskey has not been charged criminally for the shooting.Late Tuesday, two people were killed and one person was wounded in a shooting amid the demonstrations. Kyle Rittenhouse, 17, of Antioch, Illinois, was charged in connection with the shootings."Let me be clear: the violence must stop – whether in Minneapolis, Portland, or Kenosha. Too many heroes have died defending our freedoms to see Americans strike each other down," Pence saidPence promises coronavirus vaccine by year’s endPence, who has spearheaded the White House’s coronavirus task force, committed that a vaccine will be ready by the end of the year. While there is incredible urgency to develop a vaccine given 180,000 US coronavirus deaths so far in 2020, there are doubts among public health experts a vaccine can be distributed so quickly.Last week, Joe Biden said 'no miracle is coming.' What Joe doesn't seem to understand is that America is a nation of miracles and I'm proud to report we're on track to have the world's first safe, effective coronavirus vaccine by the end of this year,” Pence said.The White House has launched "Project Warp Speed," with the goal of producing 300 million vaccine doses by January. Dr. Anthony Fauci told Reuters earlier this week it is important for a vaccine to be proven effective. "One of the potential dangers if you prematurely let a vaccine out is that it would make it difficult, if not impossible, for the other vaccines to enroll people in their trial," he told the outlet.Jack Brewer speaks following insider trading chargesFormer NFL star Jack Brewer delivered an RNC speech on Wednesday despite being charged with insider trading earlier in the month.Brewer’s charges are civil and not criminal in nature.He is accused of selling 100,000 shares of a “pennystock” in 2017 after allegedly receiving insider information about the stock’s value.Brewer said he is a lifelong Democrat, “But I support Donald Trump. Let me be clear. I didn't come here for the popularity or the praise, the likes or the retweets. I'm here as a servant to God, a servant to the people of our nation and a servant to our president." 3051

VALLEY CENTER, Calif. (KGTV) - A fire broke out Friday afternoon in Valley Center, threatening the small north San Diego County community.The flames were reported about 1:30 p.m. in brush near Miller Lane and Cole Grade Lane, an area surrounded by farms and homes. The cause was unknown, Cal Fire said.At 10 a.m. Saturday, Cal Fire lifted all evacuations. #MillerFire in Valley Center [update] Effective immediately all evacuation orders have been lifted. Access to Coyote Run and Rabbit Run will be limited to residents only. Fire crews will remain at scene throughout the day, so please drive with caution when in the area. pic.twitter.com/twGTkf45b2— CAL FIRE/SAN DIEGO COUNTY FIRE (@CALFIRESANDIEGO) October 26, 2019 Children in grades K-8 were already out of school Friday due to parent-teacher conferences, according to Pauma Valley school district officials. Valley Center High School initially had students shelter in place but children were in the process of being transported off campus about 2:30 p.m. Video showed several school buses in front of the campus.As of Sunday morning, Cal Fire said the fire burned 37 acres and was 90 percent contained. One home was damaged and three outbuildings were destroyed.See Interactive Map of Southern California wildfiresA Friday night football game between Valley Center and Escondido High Schools was canceled due to the blaze. SDG&E's Sky Maverick, which assisted in the Sawday fire in Ramona Friday morning, was deployed to Valley Center, according to Twitter.Check 10News Pinpoint WeatherThe San Diego Imperial Counties Red Cross sent a volunteer team to the Valley Center Community Center to provide support for evacuees. It’s an eerie sight up Coyote Run. Hot spots from #Millerfire still sparking on both sides of the road. Crews are mopping them up just a few yards from homes trying to protect them from flare-ups. Live coverage on @10News pic.twitter.com/Lkm0HcDwOG— Jeff Lasky (@10NewsLasky) October 25, 2019 1983