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The first large head-to-head comparison of two opioid addiction medications found that, although they were equally effective in getting people off of high levels of opioids, users had a significantly more difficult time starting a regimen of naltrexone, compared with buprenorphine.Buprenorphine is commonly known by the the brand name Suboxone, and naltrexone is sold under the brand name Vivitrol.The study, published Tuesday in the Lancet, looked at 570 patients with opioid addiction at eight inpatient treatment centers across the country for 24 weeks. Half of the group was assigned to naltrexone and the other half to bupenorphine.Six percent of those enlisted to use buprenorphine were unable to start their treatment, whereas 28% of those assigned to naltrexone dropped out before starting the therapy. 824
The chairwoman of the Republican National Committee, Ronna McDaniel, has tested positive for coronavirus, according to multiple reports.The New York Times reports McDaniel is experiencing mild symptoms and is quarantining in Michigan.She was last with President Donald Trump last Friday, and the NYT says she received her diagnosis on Wednesday. 353
The CDC says there's yet another illness that you need to be aware of; one that has serious outcomes as doctors warn of a possible outbreak of AFM, or Acute Flaccid Myelitis, which can cause paralysis in children.When Kinley was just 5 years old, what started as a stomach and headache turned into exhaustion. By the time her parents got her to the hospital, she was admitted into the ICU. By the next morning, she was on life support and paralyzed in all limbs.Now 11, hers is one of the 633 nationwide cases to date of AFM. Dr. Janell Routh, a pediatrician and AFM Team Leader for the CDC, says they've been tracking the neurologic condition since 2014.“Something changed in 2014, the epidemiology changed and we saw an increase in cases,” Routh said. “We confirmed 120 cases in 2014. We think that new epidemiology suggests that we have either a new cause for this condition or a cause that somehow changed to become more virulent.”By 2018, the number of cases had doubled. Which means 2020, the year that seems to be affected by everything, will see more cases. The CDC says the type of virus that causes AFM starts with a basic fever. Which then may go away and come back.“Most parents don’t necessarily think much about a fever and the sniffles- if parents do see limb weakness so their child complaining of pain maybe headache or back pain and weakness in one or more limbs that is a sign they need to seek medical care immediately,” Routh said.Routh says AFM progresses rapidly by attacking the gray matter of the spinal cord. Paralysis can set in in a matter of hours or days.“I remember one mother telling me that her child laid limply on her chest, couldn’t move. Those are signs that they really need to call their pediatrician or go the ER and get evaluated,” Routh said.As it's a relatively new syndrome, there's a lot we don't know. There's no lab test to diagnose it and there's no vaccine. 90% of the cases are in children under the age of 18 with the average age being 5. Some recover, some have long term complications like Kinley, who is now 11 and still on a ventilator. She's regained use of her right leg and foot and uses it for school work and painting.“I’ve definitely seen how this condition can affect children and their families, not just from a physical standpoint but from an emotional standpoint disrupting the lives of families,” Routh said.The CDC is now trying to track patients and outcomes, tracking the recovery of those who have been diagnosed and researching those who may be at risk. They do know that it seems to affect kids in late August and early September, and prevention is similar to what you'd do for other viruses like COVID-19. Hand washing, staying home if you're sick, and having good cough etiquette.“AFM is a medical emergency and so if parents do see signs of limb weakness in their children after a viral illness and in those late summer early fall months - call your pediatrician go to the emergency room,” Routh said.And she says, while there is so much focus on COVID-19, it's definitely not the only virus that is spreading. 3093
The death of unarmed black men at the hands of police is not an issue often broached in the epicenter of the technology industry.But Ebele Okobi, Facebook's public policy director for Africa, hopes the death of her 36-year-old brother, Chinedu, can begin to change attitudes in the clubby and largely white world of Silicon Valley.The Morehouse College graduate died earlier this month after being tased during a confrontation with sheriff's deputies near San Francisco."It doesn't matter what school you went to," said Ebele Okobi, 44. "You can go to Harvard. You can work in tech. Every black American will tell you they live in a state of constant anxiety. Every black man will tell you they can work at Google, they can be a senior person at Facebook or Apple but when you're driving and you're a black man, you recognize the danger that you're in."The circumstances surrounding Okobi's death on the afternoon of October 3 remain unclear.The San Mateo County Sheriff's Office said deputies encountered Okobi "running in and out of traffic" on a street in Millbrae, a city about 30 miles northwest of Silicon Valley.Okobi "immediately assaulted" a deputy who got out of his vehicle, the statement said. There was a struggle with other deputies who responded.Okobi was taken into custody and transported to a hospital, where he died. A deputy was treated for injuries at a hospital, the sheriff's office said.Tasers were discharged at Okobi three to four times, according to San Mateo County District Attorney Stephen Wagstaff.One or more deputies fired Tasers. It's unclear how many times Okobi was struck, he said.An autopsy has been completed but investigators were awaiting toxicology reports, which could take four to six weeks, Wagstaff said.The district attorney's office, which investigates officer involved deaths, was still interviewing witnesses and combing through surveillance footage in the area, according to Wagstaff."We have hit a period of great concern regarding Tasers," said Wagstaff, adding that Okobi's death was the county's third since December during law enforcement encounters that involved the high-voltage stun guns.Wagstaff said it's still unclear if the Taser contributed to Okobi's death.The district attorney said his office will release video of the incident by mid-December.Ebele Okobi, whose family has retained an attorney, said prosecutors told her there was drone video of the encounter. She said the family's first contact with authorities was Wednesday.Prosecutors would not tell the family whether her brother can be seen assaulting a deputy in the video, she said.The sheriff's office said four deputies and a sergeant were involved in the incident. Deputies in "critical incidents where a death occurs are routinely placed on paid administrative leave, pending investigation," the office said."When the district attorney's office completes an investigation of sheriff's office staff, the San Mateo County Sheriff's Office will often conduct a separate administrative investigation in regards to compliance with our policies," the statement said.Chinedu Okobi graduated in 2003 with a degree in business administration from Morehouse College in Atlanta.He grew up in the San Francisco area as the youngest son of a Nigerian-American family, Ebele Okobi said.Chinedu Okobi, who has a 12-year-old daughter, spent the last decade struggling with mental health issues and may have stopped taking medications earlier this year, according to his sister."He was really gentle," Ebele Okobi recalled. "He was someone people connected to all his life. He was a kind person. He loved poetry. He recorded poetry. He recorded rap. He was also very spiritual and deeply religious."She marveled at the support from executives and others at Facebook."There definitely something insular about tech and definitely something insular about Silicon Valley," she said."But my colleagues at Facebook basically organized themselves and just kept telling the story and saying, this is important. Facebook's mission and Facebook's power to do good in the world -- that's the reason I work there. I've never seen this kind of solidarity and this kind of care."Ebele Okobi said that as a black woman she long feared losing a loved one in a violent police encounter.In 2014, after the birth of her son, she moved her family to London."I think it takes a huge amount of emotional courage to raise black children here and I knew that I didn't have it," she said. "I don't have the emotional fortitude to have a black husband and a black son in America. It's not as if I could take everyone I love with me."She said she hopes her brother's death resonates in Silicon Valley's corridors of influence and privilege."People who never thought this could happen to anybody they know, now know that it can," Ebele Okobi said."I hope this becomes a catalyst for more informed conversations" about police encounters with unarmed black men and the mentally ill as well as the use of Tasers on suspects. "My hope is that now that more people are proximate to these problems that they do something about them."A memorial fund to make donations to the Equal Justice Initiative?was set up in Chinedu Okobi's name. 5227
The crude oil crash just got worse.US oil prices plummeted nearly 7% on Tuesday to .43 a barrel. That marks the cheapest closing price since late October 2017.The latest deep selloff coincided with more mayhem on Wall Street. The Dow shed more than 600 points on Tuesday as fears about slowing earnings and economic growth deepen."In times of crises, all assets correlate," said Matt Smith, director of commodity research at ClipperData. "Crude has gotten caught up in the flight from equities."In the span of just seven weeks, crude has gone from spiking to nosediving into a bear market. Fears of a new supply glut and weakening demand have wiped out 30% of its value since hitting a four-year high of a barrel in early October.Crude has sold off by about 7% twice in the past week. The November 13 decline of 7.1% was the worst in three years.Beyond the stock market tumble, energy analysts saw few new reasons for the energy plunge."Oil traders are overwhelmed by bearish news," said Clay Seigle, managing director of oil at Genscape. "The broad selloff in equities has traders concerned about the possibility of an economic slowdown, which could reduce demand for oil products."One new development may have also helped weigh on oil prices. President Donald Trump signaled on Tuesday he won't punish Saudi Crown Prince Mohammed bin Salman for the death of Washington Post journalist Jamal Khashoggi."It could very well be that the Crown Prince had knowledge of this tragic event -- maybe he did and maybe he didn't!" Trump said in a statement. Energy traders may be interpreting the White House comments on US-Saudi ties as a sign that the kingdom won't aggressively cut oil production to support the market. Trump has repeatedly urged Saudi Arabia and OPEC not to do anything that will lift prices."If we broke with them I think your oil prices would go through the roof," Trump told reporters at the White House Tuesday.He also said he was "not going to destroy the economy of our country" over the murder of Saudi journalist and Washington Post contributor Jamal Khashoggi.OPEC is scheduled to meet next month in Vienna to weigh a potential output shift."You've got to think OPEC will be looking to make a sizable cut to try to reign in supplies and find a floor for prices here," said ClipperData's Smith.Not long ago, OPEC was under pressure to ramp up output in a bid to avoid 0 oil. Traders feared a supply shortage caused by the Trump administration's sanctions on Iran, the world's fifth biggest oil producer.However, the Trump administration took a softer approach on Iran than it initially signaled. Temporary waivers were granted to China, India and other buyers.By that point, Saudi Arabia, Russia and the United States had already ramped up output, leaving the market with a potential glut. US production has been especially strong, driven by the shale boom in the Permian Basin of West Texas. US output alone is expected to spike by 2.1 million barrels per day in 2018.At the same time, the global growth worries spooking Wall Street threatens to eat into demand. The International Energy Agency warned last week of "relatively weak" demand for oil in Europe and advanced Asian countries as well as a "slowdown" in India, Brazil and Argentina."The outlook for the global economy has deteriorated," the IEA wrote.The-CNN-Wire 3361