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Dr. Anthony Fauci, the nation's top expert on infectious diseases, spoke Wednesday to Harvard's School of Public Health amid the record-breaking spread of COVID-19 and impending announcements on vaccines.Watch the event below:Fauci's comments come amid the deadliest stretch of the pandemic to date.An average of 2,600 Americans are dying of the virus every day to go with an average of more than 200,000 new infections. The surge in the spread of the virus comes as many hospitals are full — a record 104,000 people in the U.S. are battling the virus in a hospital.Despite those grim numbers, Fauci said earlier this week that he expects things to get worse. He told CBS News on Monday that the U.S. still has not seen the expected spread of the virus that was facilitated by travel and indoor gatherings during the Thanksgiving holiday.Fauci's comments also come as the FDA weighs Emergency Use Authorization for a COVID-19 vaccine candidate made by Pfizer. Officials at the agency are expected to meet Thursday to discuss granting authorization, meaning Americans could receive initial doses as soon as next week.The event also comes a day after president-elect Joe Biden formally introduced Fauci as a top medical adviser in his administration. Biden also said he worked with Fauci to establish three goals to fight COVID-19 in his first 100 days in office: Institute mask mandates where possible, give out 100 million doses of vaccine and get as many kids back to in-person learning as possible. 1508

Dr. Anthony Fauci delivered more good news regarding a potential coronavirus vaccine, indicating some Americans could begin getting vaccinated by the end of this month.During an interview with CNN’s Wolf Blitzer, Fauci, the director of the National Institute of Allergy and Infectious Diseases National Institute of Allergy and Infectious Diseases, said it’s possible a vaccine could begin reaching some Americans by the end of the month, but was confident some would begin getting vaccinated by the end of the year.Fauci’s declaration came on the same day Pfizer said that its Phase 3 vaccine candidate was showing an effectiveness of over 90%. Fauci said the announcement was promising, but a few more questions need to be addressed before it is given approval. Fauci said that things like the vaccine’s durability and effect on the elderly are among concerns that still need to be tackled.“We may have doses that we’re able to give to people by the end of November, beginning of December,” Fauci told CNN’s Blitzer. “Now you have to go through the hoops of making sure all of the I’s are dotted and the T’s are crossed about the safety and regulatory aspects of it, but we would be giving vaccine, very likely, by the end of this year. That is good news.”Last month, the FDA put into place guidelines on approving a vaccine, which was more restrictive than what the White House had hoped for. The FDA noted that a vaccine candidate must be at least 50% effective. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.“In addition to outlining our expectations for vaccine sponsors, we also hope the agency's guidance on COVID-19 vaccines helps the public understand our science-based decision-making process that assures vaccine quality, safety and efficacy for any vaccine that is authorized or approved,” Peter Marks, M.D., Ph.D., director of the FDA's Center for Biologics Evaluation and Research, said.While it is possible some will begin getting vaccinated in the coming weeks or months, questions remain on how soon a majority of the country will have the opportunity to become vaccinated. The first Americans slated to become vaccinated will be health care workers and people with a high risk of coronavirus complications, such as the elderly and those living in assisted living facilities, according to an NPR report.Given that Pfizer’s vaccine candidate is showing a high level of effectiveness, Fauci called the development “extraordinary.”"We know there's light at the end of the tunnel, but that doesn't mean that we're going to give up the important public health measures that we continually still have to do every single day,” Fauci said.While there is urgency for both public health and economic reasons for a vaccine, some experts have expressed concern over the speed of a vaccine and whether the expedited timeline is long enough to demonstrate efficacy.Even though a vaccine could be ready by year’s end, trials will be expected to continue for over a year to monitor for possible side effects.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.”Pfizer said based on current projections, it expects to produce globally up to 50 million vaccine doses in 2020 and up to 1.3 billion doses in 2021. 3823

DUBLIN, Calif. (AP) — Authorities say actress Felicity Huffman has been released from a federal prison in California after serving 12 days of a 14-day sentence for her role in the college admissions scandal.The U.S. Bureau of Prisons says the "Desperate Housewives" star was released from the low-security prison for women in the San Francisco Bay Area on Friday morning.Under prison policy, inmate scheduled for weekend release are let out on Friday.Huffman reported to the prison on Oct. 15, with one day of credit for the time she spent in jail on the day she was originally arrested. 595

Disney CEO Bob Iger has revealed a tentative name for the company's new streaming service.In an interview with Variety, Iger refers to the service as Disney Play, which hopes to rival the crowded field that includes Netflix, HBO, Hulu, and Amazon Prime.In the past, Iger has suggested that the new streaming service will cost less than its competitors. 375

EL CAJON (CNS) - A 49-year-old man was arrested today on suspicion of fatally shooting a man in an unincorporated area near El Cajon. Daniel Christopher Allen, who lives in the unincorporated area, was booked into the San Diego Central Jail for murder, according to the San Diego County Sheriff's Department.The shooting was reported in the 6000 block of Stallion Oaks Road, southeast of Dehesa Road and northeast of the Sycuan Resort, around 10:30 p.m. Thursday, sheriff's Lt. Thomas Seiver said.Before deputies arrived, an acquaintance of the victim drove him about a mile and a half from the shooting scene, Seiver said.Deputies stopped the vehicle on Stallion Oaks Road near Dehesa Road and found the victim inside suffering from a gunshot wound. It was not immediately clear if Allen is the acquaintance.The victim, whose name and age were not immediately available, was pronounced dead at the scene, Seiver said. 926