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"Trainspotting 2" star Bradley Welsh has been shot dead in Scotland, the UK's Press Association agency has reported.The actor -- who appeared as gangland figure Doyle in the sequel to the hit movie about a group of heroin addicts in Edinburgh -- was killed in Scotland's capital on Wednesday night, the agency said.Police said they were called to an incident in the city at around 8:00 p.m. (3:00 p.m. ET), and a man was found seriously injured before dying at the scene."His death is being treated as suspicious and inquiries are continuing," police said in a statement provided to CNN.Welsh starred alongside Ewan McGregor, Ewen Bremner and Jonny Lee Miller in the popular follow-up movie, and has also appeared on TV series "Danny Dyer's Deadliest Men."The avid boxer also owned a gym in Edinburgh.Irvine Welsh, the writer of the Trainspotting novel on which the first movie was based, tweeted his condolences to his "amazing and beautiful friend.""Thanks for making me a better person and helping me to see the world in a kinder and wiser way," tweeted Welsh, who was not related to the actor. 1109

A father of six has died after a wave struck him on a North Carolina beach and slammed him to the sand, breaking his neck, his wife said on Twitter.Lee Dingle, 37, was playing on Oak Island's beach with three of his kids Thursday when the wave hit him, Shannon Dingle said. The force of the impact broke his neck and made his throat swell so much that his brain was deprived of oxygen for too long to recover, she said.He died a day later despite the efforts of some heroes, including their kids, to try to save him, she said."My partner, my love, and my home died today after a freak accident," 608

The drug ketamine is used as an anesthetic, a pain reliever or even a club drug. But now, a ketamine-like drug could soon be approved by the FDA to help people fighting severe depression. Sally Owens is one patient undergoing ketamine treatment. “You feel secure in and grounded, even though you're in a dream state,” Owens says of the treatment. “And in an hour, you come out of it and you're feeling better.” The retired nurse started getting IV ketamine treatments after fighting depression with antidepressants for most of her adult life, with no success. But after two sessions at Vitalitas, a Denver ketamine infusion center, she saw results. “I was doing more things around the house and getting out and and doing more things with friends,” she says. Owens says she’s excited to hear the FDA is considering a more accessible, less potent nasal spray similar to ketamine. “You could essentially think of esketamine as half of ketamine,” describes Dr. Roman Langston, who treats patients with ketamine. Esketamine would be for people with severe depression who haven't benefited from at least two different therapies, the doctor says. 300 million people around the world are affected by severe depression. Drug makers hope the spray can help 30 to 40 percent of patients, who don't respond to antidepressants. Antidepressants can take weeks to take effect, while they say nasal spray benefits start after four hours. Dr. Langston says FDA approval could make more people comfortable using the drug, commonly known as a party drug. Right now, it's not covered by insurance. Sessions can range from 0 to 0 for a session. “If they qualify for coverage through their insurance company, maybe it's a copay, and they can give it a try and it could make a huge difference in their life,” he says.Dr. Langston says it remains to be seen what the long-term consequences of esketamine are. 1907

A man is accused of setting fire to cardboard that a homeless man was sleeping under in Southern California. The Glendale Police Department says 32-year-old Richard Smallets intentionally set the fire on a sidewalk near a popular shopping center on Sept. 12. Police responded to the scene at about 1:22 a.m. to assist firefighters called to extinguish the fire. An investigation revealed the homeless man was awoken by the odor of smoke, realized the cardboard above him was on fire and unsuccessfully attempted to put out the flames with bottled water. Later that afternoon, police say detectives retrieved video surveillance from a nearby business that captured a man intentionally lighting the cardboard on fire and then taking photos. Officers later came in contact with Smallets at nearby Central Park. After questioning, he was identified as the suspect and subsequently placed under arrest on an arson charge. The next day, the Los Angeles County District Attorney’s Office filed an attempted murder charge against Smallets. His bail has been set at million. The motive behind the crime is unknown at this time. 1133

Some people see the landmark decision out of Oklahoma as a turning point in the nation's fight against opioids.A judge is ordering drug maker Johnson & Johnson to pay over half a billion dollars for its role in the crisis.One emergency room doctor hopes their unique program combined with court battles against drug companies might finally help fix the crisis.“Nationally this is a huge epidemic,” says Dr. Ashley Curry, an emergency psychiatrist with Denver Health.It's estimated that over 130 people die every single day from an opioid overdose. And even for those who recognize they may have a problem, it can take months to get help and a prescription for the medication they might need to help them.Curry is part of the team of doctors at Denver Health's "Treatment on Demand" program.“We recognized that there was really a gap in when people were ready to start treatment and how quickly they could access that treatment, so we were trying to fill that gap,” Curry says.Their solution? Same day treatment.“Day or night, 24/7, our emergency room is open and people can come in and start on medication-assisted treatment,” Curry says.About 300 patients so far have used the hospital's emergency department for treatment, and about 70 percent have continued with clinic follow-ups.Curry hopes that Monday’s verdict against drug maker Johnson & Johnson means the tide might finally be turning.“I think that verdict really helps represent like the collective consciousness about how problematic opioid use has become for our country,” Curry says. “We are recognizing this is a major problem and it's a public health crisis. 1645